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基于數(shù)據(jù)挖掘的舒鵬教授治療胃癌臨床病案的回顧性研究

發(fā)布時(shí)間:2018-01-01 14:32

  本文關(guān)鍵詞:基于數(shù)據(jù)挖掘的舒鵬教授治療胃癌臨床病案的回顧性研究 出處:《南京中醫(yī)藥大學(xué)》2016年碩士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 胃癌 數(shù)據(jù)挖掘 舒鵬 病案回顧性研究


【摘要】:研究目的以江蘇省中醫(yī)院舒鵬教授臨床治療胃癌的實(shí)踐經(jīng)驗(yàn)為基礎(chǔ),以數(shù)據(jù)挖掘技術(shù)為手段,對(duì)舒鵬教授近年來(lái)辨治胃癌的臨床經(jīng)驗(yàn)及學(xué)術(shù)思想進(jìn)行歸納、探討和分析,并進(jìn)一步總結(jié)舒鵬教授治療胃癌的經(jīng)驗(yàn)及學(xué)術(shù)思想,以供同道借鑒,為提高中醫(yī)藥在胃癌治療中的療效做出努力。研究方法對(duì)舒鵬教授2012年1月至2015年1月門診診治的胃癌病案進(jìn)行整理和收集,嚴(yán)格按照納入標(biāo)準(zhǔn)和排除標(biāo)準(zhǔn)進(jìn)行篩選,將符合標(biāo)準(zhǔn)的162例胃癌病案資料建立臨床病案數(shù)據(jù)庫(kù),運(yùn)用頻數(shù)分布、聚類分析等方法著重挖掘病案中癥狀、辨證分型、方藥之間的規(guī)律,結(jié)合舒鵬教授的臨證經(jīng)驗(yàn)及學(xué)術(shù)思想,對(duì)挖掘結(jié)果進(jìn)行總結(jié)、歸納和分析。研究結(jié)果在舒鵬教授診治的這162例胃癌患者中,男性107例,女性55例,年齡在25-85歲之間,平均年齡60±1.09歲。所有診次癥狀中,頻數(shù)芝10的有13種,分別為乏力(59例,36.42%)、納差(54例,33.33%)、噯氣(31例,19.14%)、便溏(28例,17.28%)、泛酸(24例,14.81%)、畏寒(23例,14.20%)、便秘(12例,7.41%)、胃脹(16例,9.88%)、進(jìn)食梗阻(13例,8.02%)、嘈雜(13例,8.02%)、嘔吐(12例,7.41%)、失眠(11例,6.79%)、胃痛(10例,6.17%)。采用將中醫(yī)證型規(guī)范成單證的方式,將單證按照虛證和實(shí)證進(jìn)行分類,結(jié)果表明虛證中常見(jiàn)證型為脾胃氣虛(54.32%)、脾胃虛寒(26.54%)及氣陰兩虛(19.14%)、胃陰虛(17.28%),而癌毒內(nèi)聚(27.16%)、胃氣郁滯(24.07%)及寒濕困脾(18.52%)、肝脾不調(diào)(12.35%)是主要的實(shí)證。舒鵬教授選用的中藥共18類,其中頻數(shù)在100次以上,頻率在3%上的藥物僅8類,累計(jì)頻率占88.43%,分別為消食藥、補(bǔ)虛藥、化痰止咳平喘藥、活血化瘀藥、行氣藥、清熱藥、收澀藥及溫里藥。舒鵬教授治療胃癌使用藥比較廣泛,共使用中藥152種,總計(jì)3354昧次,頻率70%也僅有13味中藥:炙甘草(98.15%)、炒稻芽(93.83%)、炒麥芽(93.83%)、黃芪(90.74%)、山楂(90.74%)、神曲(90.12%)、雞內(nèi)金(87.04%)、白術(shù)(82.72%)、陳皮(77.16%)、法半夏(76.54%)、黨參(72.22%)、浙貝母(70.37%)。研究結(jié)論通過(guò)研究發(fā)現(xiàn),胃癌的臨床常見(jiàn)癥狀:為乏力、納差、便溏、便秘、胃脹、失眠、畏寒、進(jìn)食梗阻、噯氣、泛酸、嘈雜、胃痛及嘔吐。常見(jiàn)證型以脾胃氣虛、癌毒內(nèi)聚、脾胃虛寒、胃氣郁滯及氣陰兩虛、寒濕困脾、胃陰虛、肝脾不調(diào)為主。舒鵬教授治療胃癌常用藥物補(bǔ)虛藥、消食藥、化痰止咳平喘藥、行氣藥、活血化瘀藥、清熱藥、收澀藥及溫里藥,如炙甘草、炒稻芽、炒麥芽、黃芪、山楂、神曲、雞內(nèi)金、白術(shù)、陳皮、法半夏、黨參、浙貝母等?傮w治法為健脾養(yǎng)胃,扶正固本為主,祛邪為輔。
[Abstract]:The purpose of the study is based on the practical experience of Jiangsu Province Traditional Chinese Medicine Hospital professor Shu Peng treatment of gastric cancer, according to data mining technology as a means of Professor Shu Peng's academic thought and clinical experience in treating gastric cancer were summarized, discussion and analysis, and further summarizes the experience and academic thoughts of professor Shu Peng in treatment of gastric cancer, for the colleagues to make efforts for reference. To improve the efficacy of traditional Chinese medicine in the treatment of gastric cancer. The research methods of Professor Shu Peng in January 2012 to January 2015 outpatient treatment of gastric cancer cases were collected and collected, in strict accordance with the inclusion criteria and exclusion criteria were selected to establish the clinical medical record database of medical records of 162 cases of gastric cancer will meet the standard, the use of frequency distribution, cluster analysis methods focus on the mining of medical records in the symptoms, syndromes, prescriptions between law, combined with Professor Shu Peng's academic thought and clinical experience, the results of data mining 榪涜鎬葷粨,褰掔撼鍜屽垎鏋,

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