本文關鍵詞：健脾祛濕法治療兒童期亞急性濕疹的臨床研究　出處：《南京中醫(yī)藥大學》2017年碩士論文　論文類型：學位論文

  更多相關文章： 健脾祛濕法 兒童濕疹 亞急性 臨床研究

【摘要】：目的:本課題從中西醫(yī)兩方面對濕疹的認識進行概述與總結。并將導師自擬健脾祛濕經驗方對兒童亞急性濕疹進行臨床研究,客觀評價健脾祛濕法在治療兒童亞急性濕疹的療效與優(yōu)勢。方法:收集來自江蘇省中醫(yī)院皮膚科自2016年04月-2017年02月的門診患兒共80例,將患兒按隨機原則分為健脾祛濕方藥治療組41例、西替利嗪滴劑對照組39例。方藥由本院藥房統(tǒng)一煎煮,每日2次,早晚飯后半小時各1袋;對照組予西替利嗪滴劑,每晚1次,飯后半小時溫水調服。兩組均聯(lián)合長效抗菌材料潔悠神外用。4周為一個療程。分別通過濕疹面積及嚴重度指數(Eczema Area and Severity Index,EASI)評分、瘙癢程度的直觀模擬標尺(Visual Analogue Scale,VAS)評分、兒童皮膚病生活質量指數(Children,s Dermatology Life Quality Index,CDLQI)量表、療程結束后隨訪復發(fā)情況來觀察療效。結果:健脾祛濕方藥組4周后總有效率為60.98%,西替利嗪滴劑4周后總有效率為35.90%,相比總有效率差異性顯著(P0.05);治療組治療前EASI分值7.38±1.58,治療后EASI分值2.37± 1.48,對照組治療前EASI分值7.34±1.43,治療后EASI分值3.37±159,兩組用藥前相比分值相近,無統(tǒng)計學意義(P0.05),治療后相比,西替利嗪滴劑組分值明顯高于健脾祛濕方藥組,二者有顯著性差異(P0.05);治療組治療前瘙癢程度積分6.15±1.46,經治后降為2.90±1.09,對照組治療前瘙癢程度積分6.13±1.28,治療后降為3.87±1.66,兩組用藥前相比分值相近,無顯著性差異(P0.05),經治后相比有顯著性差異(P0.05);治療組治療前CDLQI評分11.66±2.71,治療后CDLQI評分5.51±1.08,對照組治療前CDLQI評分12.05±2.97,經治后CDLQI評分8.08±2.04,兩組用藥前相比分值相近,無顯著性差異(P0.05),治療后相比有顯著性差異(P0.05)。結論:健脾祛濕方藥加減治療兒童亞急性期濕疹明顯優(yōu)于西藥組對照,療效顯著,復發(fā)率低,具有臨床探討價值。
[Abstract]:Objective: to summarize and summarize the cognition of eczema from two aspects of traditional Chinese and western medicine, and to make a clinical study on children subacute eczema with self-made prescription of invigorating spleen and removing dampness. Objective to evaluate the curative effect and advantage of tonifying spleen and removing dampness in treating children with subacute eczema. Methods: from April 2016 to February 2017, 80 outpatients were collected from dermatology department of Jiangsu Provincial traditional Chinese Medicine Hospital. According to the random principle, the children were divided into two groups: the treatment group (n = 41) with tonifying spleen and removing dampness, and the control group (n = 39) with cetirizine. The control group was given cetirizine drops once a night. Take warm water for half an hour after meal. Both groups were treated with long-term antibacterial material Jieyoushen for a course of 4 weeks. Eczema area and severity index (. Eczema Area and Severity Index. EASI) score, visual Analogue scale scale score of itching degree and children's quality of life index. S Dermatology Life Quality index (CDLQI). Results: the total effective rate of invigorating spleen and removing dampness prescription group was 60.98 after 4 weeks, and that of cetirizine drops was 35.90% after 4 weeks. Compared with the total effective rate, the difference was significant (P 0.05). The EASI score was 7.38 鹵1.58 before treatment and 2.37 鹵1.48 after treatment in the treatment group and 7.34 鹵1.43 before the treatment in the control group. After treatment, the score of EASI was 3.37 鹵159.The scores of the two groups were similar before and after treatment, and there was no significant difference between the two groups (P 0.05). The score of cetirizine drop group was significantly higher than that of invigorating spleen and removing dampness prescription group, there was significant difference between the two groups (P 0.05). The score of pruritus before treatment was 6.15 鹵1.46 in the treatment group, and decreased to 2.90 鹵1.09 after treatment, while that in the control group was 6.13 鹵1.28 before treatment. After treatment, it decreased to 3.87 鹵1.66. The scores of the two groups before treatment were similar, there was no significant difference (P 0.05), and there was significant difference after treatment (P 0.05). The CDLQI score before treatment was 11.66 鹵2.71 in the treatment group, the CDLQI score was 5.51 鹵1.08 after treatment, and the CDLQI score before treatment in the control group was 12.05 鹵2.97. After treatment, the CDLQI score was 8.08 鹵2.04.The scores of the two groups were similar before treatment, but there was no significant difference between the two groups (P0.05). Conclusion: the addition and subtraction of tonifying spleen and removing dampness prescription in treating children with subacute eczema is better than that in western medicine group, the curative effect is significant, the recurrence rate is low, and it has clinical value.
【學位授予單位】：南京中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R275.9

【參考文獻】

相關期刊論文 前10條

1 王和平;王玉蕾;鄭躍杰;李萍;鄧繼巋;;濕疹患兒腸道菌群高通量測序初步探索[J];中國微生態(tài)學雜志;2016年07期

2 李會龍;葛寶和;;火針圍刺法治療干性濕疹驗案1則[J];湖南中醫(yī)雜志;2016年01期

3 沈桂芳;;艾苓濕疹洗劑治療小兒濕疹的臨床效果觀察[J];實用中西醫(yī)結合臨床;2015年12期

4 郭艷輝;牟昱丹;王洪聲;郭艷杰;;微生態(tài)制劑輔助治療嬰幼兒濕疹的臨床效果研究[J];大連醫(yī)科大學學報;2015年06期

5 張媛;劉永;顏敏;孫莉;李娟;;皮膚屏障與皮膚病[J];中國麻風皮膚病雜志;2015年06期

6 陳華;李嵐;鄔思遠;董逸翔;;俞景茂名老中醫(yī)兒科學術經驗述要[J];浙江中醫(yī)藥大學學報;2015年04期

7 劉芬;劉艷菊;田春漫;;蒼術麩炒前后對脾虛模型大鼠胃腸動力學的影響[J];中藥新藥與臨床藥理;2015年02期

8 陳天雷;劉丹;黃尾全;范飛翔;王麗;張弦;王明志;;生物共振治療儀治療特應性皮炎60例療效觀察及其對免疫功能的影響[J];中國皮膚性病學雜志;2014年10期

9 陳宏;程曉蕾;梁軍亮;門劍龍;;濕疹患者外周血白介素17和白介素23水平及白芍總苷治療前后的變化[J];臨床皮膚科雜志;2014年04期

10 龍劍文;;皮先明治療濕疹臨床經驗[J];湖北中醫(yī)雜志;2014年03期

，

本文編號：1364490