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  本文關(guān)鍵詞：四草飲治療肝陽(yáng)上亢型眩暈的臨床觀(guān)察　出處：《河北醫(yī)科大學(xué)》2016年碩士論文　論文類(lèi)型：學(xué)位論文

  更多相關(guān)文章： 四草飲 肝陽(yáng)上亢型眩暈 眩暈殘障程度評(píng)分 血流變 臨床觀(guān)察

【摘要】：目的:觀(guān)察四草飲治療肝陽(yáng)上亢型眩暈的臨床療效、眩暈殘障程度評(píng)分及其復(fù)發(fā)情況,并與西比靈膠囊對(duì)照,探討四草飲治療眩暈的作用機(jī)制及其對(duì)患者生活質(zhì)量方面的影響,用于指導(dǎo)臨床,探索中醫(yī)藥在眩暈中的治療作用及療效。方法:將符合本課題納入標(biāo)準(zhǔn)的肝陽(yáng)上亢型眩暈患者80例,按隨機(jī)分層原則分為治療組和對(duì)照組,治療組口服四草飲,對(duì)照組口服西比靈膠囊,兩組療程均為1月。觀(guān)察患者的臨床療效、治療前后中醫(yī)癥候積分、眩暈殘障程度評(píng)分、經(jīng)顱多普勒、血流變及復(fù)發(fā)情況等相關(guān)指標(biāo)來(lái)進(jìn)行療效評(píng)定。結(jié)果:1.臨床療效的比較:治療組總有效率為92.50%,對(duì)照組總有效率為85.00%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。2.治療前后中醫(yī)癥候積分比較:結(jié)果顯示治療組與對(duì)照組治療后中醫(yī)癥候積分與治療前比較均有顯著性差異,具有統(tǒng)計(jì)學(xué)意義(P0.01);組間比較,治療組中醫(yī)癥候積分下降幅度大于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。3.眩暈殘障程度評(píng)分的變化:治療組與對(duì)照組的眩暈殘障程度評(píng)分較治療前均有明顯改善,比較均有統(tǒng)計(jì)學(xué)顯著差異(P0.01),說(shuō)明對(duì)照組與治療組均能有效降低患者障礙評(píng)分;治療后,治療組評(píng)分水平較對(duì)照組降低明顯,兩者比較有統(tǒng)計(jì)學(xué)意義(P0.05),表明治療組對(duì)于改善患者的生活質(zhì)量療效更佳。4.治療前后經(jīng)顱多普勒指標(biāo)的比較:治療組治療前、后比較差異顯著,有統(tǒng)計(jì)學(xué)意義(P0.05);對(duì)照組舒張期的RVA、BA治療前、后比較,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),余項(xiàng)治療前、后均有統(tǒng)計(jì)學(xué)意義(P0.05);治療組與對(duì)照組對(duì)比除收縮期RVA外,均有顯著性差異,有統(tǒng)計(jì)學(xué)意義(P0.05)。5.治療前后血流變指標(biāo)的比較:治療組血液流變學(xué)中全血黏度切變率、全血低切還原粘度改變明顯優(yōu)于對(duì)照組,比較有統(tǒng)計(jì)學(xué)意義(P0.05);治療組治療后血漿粘度、全血高切還原粘度與對(duì)照組相比無(wú)明顯差異(P0.05)。6.復(fù)發(fā)率比較:治療組40例,復(fù)發(fā)2例,復(fù)發(fā)率為5%;對(duì)照組40例,復(fù)發(fā)5例,復(fù)發(fā)率為12.5%。差別有統(tǒng)計(jì)學(xué)意義(P0.05)。7.安全性觀(guān)察,治療組在臨床觀(guān)察期間未出現(xiàn)明顯不良反應(yīng)。結(jié)論:四草飲能明顯改善肝陽(yáng)上亢型眩暈的中醫(yī)癥候積分及眩暈殘障程度評(píng)分、血流變及經(jīng)顱多普勒等指標(biāo),可提高患者生活質(zhì)量、降低復(fù)發(fā)率,尤其是針對(duì)肝陽(yáng)上亢型眩暈有較好的臨床療效,可進(jìn)一步擴(kuò)大樣本量進(jìn)行臨床觀(guān)察。
[Abstract]:Objective: To observe the clinical curative effect of four grass drink, treatment of liver yang hyperactivity type of vertigo vertigo disability score and recurrence, and the control and explore the mechanism of flunarizine capsules, four Cao Yin in the treatment of vertigo and its influence on the quality of life of the patients, to guide the clinical, explore and curative effect in medical treatment effect on vertigo the. Methods: will meet the inclusion criteria of liver yang hyperactivity type of vertigo patients 80 cases, randomly divided into treatment group and control group. The treatment group was treated with four grass decoction, control group was treated with flunarizine capsules, two groups were treated for January. The clinical efficacy, TCM symptom score, vertigo and disability score, transcranial Doppler, Hemorrheology and recurrence were observed before and after treatment. Results: 1. the comparison of clinical efficacy: the total effective rate in the treatment group was 92.50%, the total effective rate of the control group was 85%, and the difference was statistically significant (P0.05). Comparison of TCM syndrome score of 2. before and after treatment: the results showed that the treatment group and control group after treatment of TCM syndrome score before treatment were significantly different, with statistical significance (P0.01); comparison between groups, the treatment group TCM syndrome score decreased than that of control group, the difference was statistically significant (P0.05). 3. changes of vertigo degree of disability score: the treatment group and the control group of vertigo disability score were significantly improved compared with before treatment, there were statistically significant differences (P0.01), description of the control group and the treatment group can effectively reduce disorder score; after treatment, group scores were lower than those in control group were compared with treatment. Statistical significance (P0.05), showed that the treatment group for improving the quality of life of patients with better curative effect. Transcranial Doppler indexes before and after treatment: 4. patients before and after treatment, the difference was statistically significant (P0.05); RVA, BA treatment control group diastolic before and after comparison, no statistically significant (P0.05), more than before and after treatment were statistically significant (P0.05); the treatment group compared with the control group except systolic RVA, significant difference was statistically significant (P0.05). Comparison of indexes of blood rheology of 5. before and after treatment: the treatment group in the blood rheology of whole blood viscosity, whole blood low shear rate viscosity change significantly better than the control group, there was statistically significant difference (P0.05); after treatment, plasma viscosity, whole blood reduction viscosity compared with the control group had no significant difference (P0.05). 6. the recurrence rate was compared: 40 cases in the treatment group, 2 cases recurred, the recurrence rate was 5%, 40 cases in the control group, 5 cases recurred, and the recurrence rate was 12.5%. The difference was statistically significant (P0.05). 7. safety observation, in the treatment group, there was no obvious adverse reaction during the clinical observation. Conclusion: four grass decoction can significantly improve the liver yang hyperactivity type of vertigo symptom scores and vertigo degree of disability score, hemorheology and transcranial Doppler indexes can improve the quality of life of patients, reduce the recurrence rate, especially for ganyangshangkang type vertigo has good clinical curative effect, can further expand the sample size for clinical observation.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R255.3

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本文編號(hào)：1346380