示蹤劑技術(shù)在腹腔鏡直腸癌根治術(shù)中應(yīng)用的價(jià)值與意義
發(fā)布時(shí)間:2021-08-12 00:25
背景和目的直腸癌(rectal cancer),是最常見的惡性腫瘤之一,死亡率、發(fā)病率一直居于惡性腫瘤的前列。其發(fā)病原因與多方面因素相關(guān),包括遺傳因素、腸道慢性病變、腸道腺瘤病變、高脂低纖維不良飲食習(xí)慣等。確診患者的年齡多位于40歲-50歲年齡組。世界流行病學(xué)調(diào)查顯示,其發(fā)病再在西歐、北美、澳大利亞等發(fā)達(dá)國家發(fā)病率最高,但在亞洲、非洲、拉美地區(qū)相對較低。直腸癌起病隱匿,早期少有嚴(yán)重的臨床表現(xiàn),就治時(shí)多已至中晚期。根治性切除是目前廣為接受的治療直腸癌的主要手段。淋巴轉(zhuǎn)移是主要轉(zhuǎn)移途徑,完整清掃轉(zhuǎn)移淋巴結(jié)關(guān)乎患者預(yù)后及術(shù)后相關(guān)治療。納米碳具有淋巴趨向性的特點(diǎn),可以指導(dǎo)清理淋巴結(jié),彌補(bǔ)既往手術(shù)過程中淋巴結(jié)清掃的不足。本實(shí)驗(yàn)基于以上的研究背景,探討納米碳淋巴結(jié)示蹤劑在腹腔鏡直腸癌根治術(shù)中應(yīng)用的價(jià)值。資料與方法統(tǒng)計(jì)自2017年1月至2019年10月在鄭州大學(xué)第二附屬醫(yī)院普外科住院行手術(shù)治療的直腸癌患者臨床資料行回顧性病例對照研究,共納入80例患者,均在術(shù)前完善MRI、CT、超聲等檢查明確淋巴結(jié)等轉(zhuǎn)移情況。40例患者于術(shù)前(1天)腸鏡下或肛門鏡下腫瘤周圍注射納米碳懸混液后再行腹腔鏡直腸癌根治手術(shù)。...
【文章來源】:鄭州大學(xué)河南省 211工程院校
【文章頁數(shù)】:57 頁
【學(xué)位級別】:碩士
【部分圖文】:
圖3.術(shù)中黑染淋巴結(jié)2??
圖2.術(shù)中黑染的淋巴結(jié)1??
圖1術(shù)中黑染的腫塊區(qū)域??
【參考文獻(xiàn)】:
期刊論文
[1]結(jié)腸癌淋巴結(jié)轉(zhuǎn)移程度與預(yù)后關(guān)系的研究[J]. 劉印,賀利平. 中國普通外科雜志. 2013(04)
[2]Performance value of high risk factors in colorectal cancer screening in China[J]. Wen Meng,Shan-Rong Cai,Lun Zhou,Qi Dong,Shu Zheng,Su-Zhan Zhang,Cancer Institute(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang Province,China Wen Meng,Department of Cardiothoracic Surgery,Hangzhou First People’s Hospital,Hangzhou 310006,Zhejiang Province,China. World Journal of Gastroenterology. 2009(48)
[3]腹腔鏡結(jié)腸癌切除術(shù)療效并不亞于開腹手術(shù)——基于COST的5年完整隨訪資料[J]. 陳志輝,Fleshman J,Sargent DJ,Green E. 中華普通外科學(xué)文獻(xiàn)(電子版). 2009(01)
[4]Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention[J]. Sheng-Xiang Rao, Meng-Su Zeng, Cai-Zhong Chen, Ren- Chen Li, Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai 200032, China Jian-Ming Xu, Xin-Yu Qin, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China Ying-Yong Hou, Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. World Journal of Gastroenterology. 2007(30)
[5]前哨淋巴結(jié)定位在結(jié)直腸癌外科中的應(yīng)用[J]. 鄭陽春. 中國普通外科雜志. 2003(11)
本文編號:3337196
【文章來源】:鄭州大學(xué)河南省 211工程院校
【文章頁數(shù)】:57 頁
【學(xué)位級別】:碩士
【部分圖文】:
圖3.術(shù)中黑染淋巴結(jié)2??
圖2.術(shù)中黑染的淋巴結(jié)1??
圖1術(shù)中黑染的腫塊區(qū)域??
【參考文獻(xiàn)】:
期刊論文
[1]結(jié)腸癌淋巴結(jié)轉(zhuǎn)移程度與預(yù)后關(guān)系的研究[J]. 劉印,賀利平. 中國普通外科雜志. 2013(04)
[2]Performance value of high risk factors in colorectal cancer screening in China[J]. Wen Meng,Shan-Rong Cai,Lun Zhou,Qi Dong,Shu Zheng,Su-Zhan Zhang,Cancer Institute(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang Province,China Wen Meng,Department of Cardiothoracic Surgery,Hangzhou First People’s Hospital,Hangzhou 310006,Zhejiang Province,China. World Journal of Gastroenterology. 2009(48)
[3]腹腔鏡結(jié)腸癌切除術(shù)療效并不亞于開腹手術(shù)——基于COST的5年完整隨訪資料[J]. 陳志輝,Fleshman J,Sargent DJ,Green E. 中華普通外科學(xué)文獻(xiàn)(電子版). 2009(01)
[4]Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention[J]. Sheng-Xiang Rao, Meng-Su Zeng, Cai-Zhong Chen, Ren- Chen Li, Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai 200032, China Jian-Ming Xu, Xin-Yu Qin, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China Ying-Yong Hou, Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. World Journal of Gastroenterology. 2007(30)
[5]前哨淋巴結(jié)定位在結(jié)直腸癌外科中的應(yīng)用[J]. 鄭陽春. 中國普通外科雜志. 2003(11)
本文編號:3337196
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