【摘要】：目的:通過對病理確診的105例肺內(nèi)磨玻璃影患者其臨床特點(diǎn)、CT圖像及結(jié)果,研究肺內(nèi)磨玻璃密度影良、惡性的危險因素。方法:根據(jù)納入、排除標(biāo)準(zhǔn)篩選出本院經(jīng)病理確診的肺內(nèi)磨玻璃密度影患者105例,回顧分析其臨床資料及影像學(xué)特點(diǎn),運(yùn)用統(tǒng)計工具SPSS19,對選擇的12個主要影響肺內(nèi)磨玻璃密度影良惡性臨床鑒別的因素進(jìn)行單因素及多因素的回歸分析。結(jié)果:本組105例患者中,惡性腫瘤患者63例(60%),良性病變患者42例(40%)。單因素統(tǒng)計數(shù)據(jù)顯示吸煙指數(shù)、年齡、G GO面積、周圍毛刺征、邊緣分葉征、胸膜凹陷征、亨氏單位(Hounsfield units,HU)值7個因素對臨床鑒別肺內(nèi)磨玻璃樣密度影良、惡性有意義(P0.05)。多因素Logistic回歸結(jié)果患者年齡(OR=1.066,95%CI:1.020~1.114,P=0.000)、周圍分葉(OR=4.419,95%CI:1.388~14.077,P=0.000)、周圍毛刺(OR=4.098,95%CI:1.401~11.987,P=0.000)。結(jié)論:根據(jù)統(tǒng)計分析及隨訪結(jié)果,故認(rèn)為患者年齡及CT影像學(xué)中邊緣分葉征、周圍毛刺征對臨床診斷肺內(nèi)磨玻璃樣密度影的良惡性有重要的指導(dǎo)意義,可以進(jìn)一步外科處理。
[Abstract]:Objective: to study the risk factors of benign and malignant intrapulmonary ground glass density by analyzing the clinical features, CT images and results of 105 patients with intrapulmonary glass grinding. Methods: according to the inclusion and exclusion criteria, 105 patients with pulmonary ground glass density diagnosed pathologically in our hospital were screened out. The clinical data and imaging features were analyzed retrospectively. the single factor and multivariate regression analysis of the 12 factors that mainly affected the clinical differentiation of benign and malignant pulmonary grinding glass density shadow was carried out by using statistical tool SPSS19,. Results: among 105 patients, 63 (60%) were malignant tumors and 42 (40%) were benign lesions. Univariate statistical data showed that smoking index, age, G GO area, peripheral burr sign, marginal lobulation sign, pleural indentation sign and Heinz unit (Hounsfield units,HU) value were significant for clinical differentiation of pulmonary ground glass density between benign and malignant (P 0.05). Multivariate Logistic regression results included age (OR=1.066,95%CI:1.020~1.114,P=0.000), peripheral lobulation (OR=4.419,95%CI:1.388~14.077,P=0.000) and peripheral burr (OR=4.098,95%CI:1.401~11.987,P=0.000). Conclusion: according to the statistical analysis and follow-up results, it is considered that the age of the patients and the marginal lobulation sign in CT imaging and peripheral burr sign are of great significance in the clinical diagnosis of benign and malignant ground glass density shadow in the lung, and can be further treated surgically.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R734.2

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