【摘要】：目的:探討磁共振擴(kuò)散加權(quán)成像(DWI)及其表觀擴(kuò)散系數(shù)(ADC)值對(duì)直腸黏液腺癌與非黏液腺癌的鑒別診斷價(jià)值。方法:回顧性分析經(jīng)手術(shù)病理證實(shí)的16例直腸黏液腺癌與64例非黏液腺癌患者的MR資料,觀察所有腫瘤的DWI信號(hào)強(qiáng)度,測(cè)量腫瘤ADC值及相對(duì)ADC(rADC)值,并繪制受試者工作特性(ROC)曲線,計(jì)算ADC值及rADC值對(duì)直腸黏液腺癌與非黏液腺癌的鑒別診斷效能。結(jié)果:16例直腸黏液腺癌中4例在DWI圖像上呈低號(hào),12例呈高信號(hào),64例非黏液腺癌中1例呈低信號(hào),63例呈高信號(hào),兩者DWI信號(hào)強(qiáng)度差異有統(tǒng)計(jì)學(xué)意義(χ2=8.333,P=0.004)。黏液腺癌的ADC值[(1.48±0.25)×10-3 mm2/s]及rADC值(1.22±0.18)均高于非黏液腺癌[(1.08±0.11)×10-3 mm2/s,(0.95±0.11)],差異均具有統(tǒng)計(jì)學(xué)意義(t=6.162,P0.001;t=5.810,P0.001)。以ADC值=1.209×10-3 mm2/s鑒別診斷黏液腺癌與非黏液腺癌的效能最高(AUC 0.923,敏感度93.8%,特異度89.1%)。結(jié)論:DWI及ADC值在直腸黏液腺癌與非黏液腺癌的鑒別診斷中具有重要價(jià)值。
[Abstract]:Objective: to evaluate the value of magnetic resonance diffusion weighted imaging (DWI) and its apparent diffusion coefficient (ADC) in the differential diagnosis of rectal mucinous carcinoma and non-mucinous carcinoma. Methods: the MR data of 16 cases of rectal mucinous carcinoma and 64 cases of non-mucinous carcinoma confirmed by operation and pathology were analyzed retrospectively. the DWI signal intensity, ADC value and relative ADC (rADC) value of all tumors were observed. The (ROC) curve of working characteristics of the subjects was drawn, and the differential diagnosis efficiency of ADC value and RADC value between rectal mucinous carcinoma and non-mucinous carcinoma was calculated. Results: among 16 cases of rectal mucinous carcinoma, 4 cases showed low signal intensity on DWI images, 12 cases showed high signal intensity, 1 case showed low signal intensity and 63 cases showed high signal intensity in 64 cases of non-mucinous adenocarcinoma. There was significant difference in DWI signal intensity between the two groups (蠂 ~ 2 鈮，

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