發(fā)布時(shí)間：2019-05-15 14:07

【摘要】：目的:探究膽囊癌病理分期及手術(shù)方式對(duì)膽囊癌預(yù)后的因素。材料與方法:回顧性分析吉林大學(xué)附屬第二醫(yī)院2010年—2015年手術(shù)并經(jīng)病理證實(shí)為膽囊癌的患者59例。術(shù)后病理所有病理均證實(shí)為膽囊癌,按Nevin分期,Ⅰ期2例,Ⅱ期12例,Ⅲ期22例,Ⅳ期12例,Ⅴ期11例。單純膽囊切除19人,膽囊癌根治術(shù)28人,姑息性手術(shù)12人。采用采用Kaplan-Meier法和Log-rank法對(duì)其病理分期、手術(shù)方法與預(yù)后的關(guān)系進(jìn)行統(tǒng)計(jì)分析,研究各病理分期、手術(shù)方式不同對(duì)膽囊癌患者生存期的影響。結(jié)果:本組研究59個(gè)病例,48例獲得隨訪,隨訪率為81.4%�？傮w生存時(shí)間為9個(gè)月。Ⅰ+Ⅱ期、Ⅲ+Ⅳ期、Ⅴ期三組中位生存時(shí)間分別為30個(gè)月、14個(gè)月和3個(gè)月。Ⅰ+Ⅱ期、Ⅲ+Ⅳ期膽囊癌患者生存率高于Ⅴ期膽囊癌患者,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);Ⅰ+Ⅱ期膽囊癌患者生存率高于Ⅲ+Ⅳ期,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。膽囊癌根治術(shù)、單純膽囊切除術(shù)及姑息性手術(shù)切除術(shù)組的中位生存期分別為:15個(gè)月、9個(gè)月、4個(gè)月。單純膽囊切除組和根治性手術(shù)組患者生存率均高于姑息性手術(shù)組患者,膽囊癌根治組生存率高于單純膽囊切除組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:膽囊癌的病理分期越早其預(yù)后越好。依病理分期選擇相應(yīng)術(shù)式,膽囊癌根治術(shù)和單純膽囊切除術(shù)效果優(yōu)于姑息性手術(shù)治療,膽囊癌根治術(shù)效果優(yōu)于單純膽囊癌根治術(shù)。
[Abstract]:Objective: To study the pathological staging of gallbladder carcinoma and the factors affecting the prognosis of gallbladder carcinoma. Materials and Methods:59 patients with gallbladder carcinoma were retrospectively analyzed in the second hospital in Jilin University in 2010. All the pathology of the post-operative pathology proved to be the gallbladder carcinoma. According to the Nevin stage, the stage I was 2 cases, the second stage was 12 cases, the stage 鈪，

本文編號(hào)：2477561