【摘要】：目的:探討肝癌肝臟切除手術后肝臟功能恢復影響因素,并建立風險預測模型。方法:回顧性分析2015年2月—2016年9月間行半肝切除手術的50例肝癌患者術的相關臨床資料,通過單變量與多變量分析對篩選出可能影響肝癌患者術后肝臟功能恢復的因素,用所得各因素及其統(tǒng)計值建立風險預測模型。結果:患者手術前吲哚菁綠15分鐘滯留率(ICGR15)、清除指數(shù)(HH15)、殘余肝臟體積/標準肝臟體積(RLV/SLV)均為半肝切除手術后肝臟功能恢復的獨立危險因素(P=0.002、P0.001、P=0.007);所得到的風險預測模型為:風險系數(shù)(R)=31.871×(RLV/SLV)-1.689×(ICG R15)-19.663×HH15;R的臨界值為0.90時,其預測術后出現(xiàn)肝功能不全的ROC曲線下面積為0.96,敏感度和特異度為97.5%和90%。結論:較低的RLV/SLV以及較高的ICGl5R和HH15是肝癌患者行肝臟切除術后肝功能不全的危險因素,所建立的預測模型有一定的風險評估價值。
[Abstract]:Objective: to investigate the influencing factors of liver function recovery after hepatectomy for hepatocellular carcinoma (HCC) and to establish a risk prediction model. Methods: the clinical data of 50 patients with liver cancer who underwent semi-hepatectomy from February 2015 to September 2016 were analyzed retrospectively. the factors that might affect the recovery of liver function in patients with liver cancer were screened out by univariable and multivariate analysis. The risk prediction model is established by using the obtained factors and their statistical values. Results: the 15-minute retention rate (ICGR15), clearance index (HH15) and residual liver volume / standard liver volume (RLV/SLV) were independent risk factors for liver function recovery after semi-hepatectomy (P 鈮，

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