直腸癌術(shù)后存活率圍手術(shù)期影響因素分析與PNAG評(píng)分建立的研究
發(fā)布時(shí)間:2018-11-25 10:39
【摘要】:目的探討臨床病理學(xué)特征和圍手術(shù)期全身炎癥狀況與直腸癌病人術(shù)后存活率的關(guān)系,建立炎癥相關(guān)直腸癌存活率預(yù)測(cè)評(píng)分系統(tǒng)。方法回顧性分析中山大學(xué)附屬第六醫(yī)院2007年6月至2012年8月就診的382例I~Ⅲ期直腸癌病人臨床資料、圍手術(shù)期炎癥狀況指標(biāo)和術(shù)后隨訪(fǎng)情況。結(jié)果全組病人的中位隨訪(fǎng)時(shí)間為46個(gè)月,1、3、5年總存活率分別為96.7%、85.6%、77.4%,1、3、5年無(wú)病存活率為86.9%、72.0%、68.1%。多因素分析結(jié)果提示,年齡、病理TNM分期、大體分型、脈管浸潤(rùn)情況和PNAG評(píng)分是Ⅰ~Ⅲ期直腸癌術(shù)后總存活率的獨(dú)立影響因素。病理TNM分期、脈管浸潤(rùn)情況、PNAG評(píng)分是Ⅰ~Ⅲ期直腸癌術(shù)后無(wú)病存活率的獨(dú)立影響因素。結(jié)論直腸癌病人術(shù)后存活率受臨床病理學(xué)特征危險(xiǎn)因素和全身炎癥狀況的影響,PNAG評(píng)分作為一項(xiàng)反映圍手術(shù)期全身炎癥狀況的綜合指標(biāo),對(duì)于存活率預(yù)測(cè)具有重要意義。
[Abstract]:Objective to investigate the relationship between the clinicopathological features and perioperative systemic inflammation and postoperative survival rate of rectal cancer patients, and to establish a prognostic scoring system for the survival rate of patients with rectal cancer associated with inflammation. Methods the clinical data of 382 patients with stage I- 鈪,
本文編號(hào):2355799
[Abstract]:Objective to investigate the relationship between the clinicopathological features and perioperative systemic inflammation and postoperative survival rate of rectal cancer patients, and to establish a prognostic scoring system for the survival rate of patients with rectal cancer associated with inflammation. Methods the clinical data of 382 patients with stage I- 鈪,
本文編號(hào):2355799
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