【摘要】：目的探討網(wǎng)織血小板檢測在急性白血病(AL)患者繼發(fā)感染時的診斷價值。方法選取189例疑似感染的AL患者,分別測定并記錄其外周血白細胞計數(shù)(WBC)、中性粒細胞(N)百分比、血小板計數(shù)(PLT)、C反應(yīng)蛋白(CRP)、降鈣素原(PCT)、網(wǎng)織血小板(RP)百分比、腋下溫度(T)。應(yīng)用受試者工作曲線(ROC)進行診斷價值比較。采用KaplanMeier生存曲線分析RP百分比與重癥感染相關(guān)的死亡率之間的關(guān)系。結(jié)果 RP百分比在診斷AL繼發(fā)感染及重癥感染時ROC曲線下面積明顯高于其他傳統(tǒng)炎癥指標;RP百分比與CRP或PCT聯(lián)合診斷感染時其靈敏度和特異度顯著提高;RP百分比9.76%的重癥感染組患者40 d累計生存率明顯高于RP百分比≥9.76%的重癥感染組患者(P0.05)。結(jié)論相較于傳統(tǒng)炎癥指標,RP百分比在診斷AL患者繼發(fā)感染及重癥感染時診斷價值最高,與CRP和(或)PCT聯(lián)合檢測有助于提高AL患者繼發(fā)感染的早期診斷率。RP百分比可作為預(yù)測死亡風(fēng)險的一項指標。
[Abstract]:Objective to evaluate the diagnostic value of reticulocyte in secondary infection in patients with acute leukemia (AL). Methods Peripheral blood leukocyte count (WBC), neutrophil (N) percentage, platelet count (PLT) C reactive protein (CRP), procalcitonin (PCT), reticulocyte (RP) percentage and axillary temperature (T). Were measured and recorded in 189 suspected AL patients. The diagnostic value of (ROC) was compared. KaplanMeier survival curve was used to analyze the relationship between the percentage of RP and the mortality associated with severe infection. Results the area under ROC curve in the diagnosis of AL secondary infection and severe infection in RP percentage was significantly higher than that in other traditional inflammatory markers, CRP or PCT. The sensitivity and specificity of ROC percentage were significantly higher than those of CRP or PCT in the diagnosis of infection. The cumulative survival rate of 9.76% patients with severe infection was significantly higher than that of patients with RP 鈮，

本文編號：2234814