宮頸癌前病變HPV感染與宮頸液基細胞早期篩查的臨床分析
發(fā)布時間：2018-08-04 20:48
【摘要】：目的探究對宮頸癌前病變患者高危型人乳頭瘤病毒(HPV)與宮頸液基細胞學(xué)檢測早期篩查的效果。方法選擇2014年3月-2017年3月在醫(yī)院就診的240例宮頸病理變化患者為研究對象,所有患者均采用高危型HPV檢查和宮頸液基細胞學(xué)檢查,進行早期宮頸癌前病變篩查并分析。結(jié)果在240例患者中,高危型HPV感染的陽性例數(shù)20例,陽性率8.33%,其中HPV16型占50.00%,HPV18型占30.00%,HPV58型占10.00%,HPV33型占5.00%,HPV31型占5.00%;TBS診斷報告顯示,異常涂片19例占7.92%;不典型鱗狀細胞(ASC)占4.17%,鱗狀細胞癌(SCC)占0.83%,鱗狀細胞癌(LISL)占1.25%,高度鱗狀上皮內(nèi)病變(HSIL)占0.83%,不典型腺細胞(AGC)占0.83%,ASC、AGC與LSIL細胞學(xué)病理檢查結(jié)果比較,差異有統(tǒng)計學(xué)意義(P0.05);HPV16與HPV18檢測陽性數(shù)與宮頸組織活檢病理結(jié)果進行比較,HPV16與HPV18在炎癥輕度宮頸癌前病變(CNⅠ)、中度宮頸癌前病變(CNⅡ)、高度宮頸癌前病變(CNⅢ)與癌中陽性比較均有統(tǒng)計學(xué)意義(P0.05)。結(jié)論高危型HPV檢查能提高宮頸癌前篩查的準確率,高危型HPV檢測聯(lián)合宮頸液基細胞學(xué)檢測應(yīng)用于早期宮頸癌前病變篩查中,能提高宮頸癌前病變篩查率,且具有科學(xué)性和準確性。
[Abstract]:Objective to investigate the effect of early screening for high-risk human papillomavirus (HPV) and cervical liquid-based cytology in patients with cervical precancerous lesions. Methods 240 patients with cervical pathological changes from March 2014 to March 2017 were selected as study subjects. All patients were screened and analyzed for early cervical precancerous lesions by high risk HPV examination and cervical liquid-based cytology. Results among the 240 cases, 20 cases were positive for high-risk type HPV infection, the positive rate was 8.33, among them, the HPV16 type accounted for 50.002% of HPV18 type and the proportion of HPV18 type was 30.00000. The diagnosis report of HPV33 type 10.00% HPV33 type 5.00% HPV31 type 5.00% TBSdiagnosis showed that the positive rate was 8.33%, and the positive rate was 8.33% among the 240 patients with HPV-positive infection, and the positive rate was 8.33%. Abnormal smear was found in 19 cases (7.92%), atypical squamous cell (ASC) (4.17%), squamous cell carcinoma (SCC) 0.833%, squamous cell carcinoma (LISL) 1.25%, high squamous intraepithelial lesion (HSIL) 0.833%, atypical glandular cell (AGC) (0.83%) and LSIL cytology. The difference was statistically significant (P0.05). The positive number of HPV16 and HPV18 and the pathological results of cervical biopsy were compared between HPV16 and HPV18 in mild cervical precancerous lesions (CN 鈪，
本文編號：2165088
[Abstract]:Objective to investigate the effect of early screening for high-risk human papillomavirus (HPV) and cervical liquid-based cytology in patients with cervical precancerous lesions. Methods 240 patients with cervical pathological changes from March 2014 to March 2017 were selected as study subjects. All patients were screened and analyzed for early cervical precancerous lesions by high risk HPV examination and cervical liquid-based cytology. Results among the 240 cases, 20 cases were positive for high-risk type HPV infection, the positive rate was 8.33, among them, the HPV16 type accounted for 50.002% of HPV18 type and the proportion of HPV18 type was 30.00000. The diagnosis report of HPV33 type 10.00% HPV33 type 5.00% HPV31 type 5.00% TBSdiagnosis showed that the positive rate was 8.33%, and the positive rate was 8.33% among the 240 patients with HPV-positive infection, and the positive rate was 8.33%. Abnormal smear was found in 19 cases (7.92%), atypical squamous cell (ASC) (4.17%), squamous cell carcinoma (SCC) 0.833%, squamous cell carcinoma (LISL) 1.25%, high squamous intraepithelial lesion (HSIL) 0.833%, atypical glandular cell (AGC) (0.83%) and LSIL cytology. The difference was statistically significant (P0.05). The positive number of HPV16 and HPV18 and the pathological results of cervical biopsy were compared between HPV16 and HPV18 in mild cervical precancerous lesions (CN 鈪，
本文編號：2165088
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