淋巴結跳躍轉移在可切除胸段食管鱗癌中的預后價值
發(fā)布時間:2018-08-02 09:33
【摘要】:目的:本研究旨在探討淋巴結跳躍轉移在食管鱗癌中的發(fā)生率,確定影響食管鱗癌淋巴結跳躍轉移的危險因素及評估淋巴結跳躍轉移在胸段食管鱗狀細胞癌患者中的預后價值。方法:收集了2011年1月1日到2013年12月31日之間在山東省腫瘤醫(yī)院接受食管癌完全切除術的113名淋巴結陽性的患者。結果:淋巴結跳躍轉移在全組的發(fā)生率為43.4%(49/113)。淋巴結跳躍轉移組的中位生存時間和5年生存率分別為18.0個月和3.0%,非淋巴結跳躍轉移組的中位生存時間和5年生存率分別為31.0個月和30.0%(P0.0001)。性別(P=0.027)、年齡(P=0.008)和腫瘤分化程度(P=0.026)與淋巴結跳躍轉移的發(fā)生有關。腫瘤位置(P=0.014),T分期(P=0.000)、N分期(P=0.000)和跳躍轉移(P=0.001)是食管鱗癌獨立的預后影響因素。結論:跳躍是食管鱗癌常見的淋巴結轉移方式之一,發(fā)生淋巴結跳躍轉移者其預后相對較差。
[Abstract]:Objective: to investigate the incidence of leaping lymph node metastasis in esophageal squamous cell carcinoma, to determine the risk factors of lymph node jumping metastasis and to evaluate the prognostic value of jump lymph node metastasis in thoracic esophageal squamous cell carcinoma. Methods: 113 patients underwent complete resection of esophageal carcinoma from January 1, 2011 to December 31, 2013 were collected. Results: the incidence of lymph node jump metastasis was 43.4% (49 / 113). The median survival time and 5-year survival rate were 18.0 months and 3.0 months in the lymph node jumping metastasis group, and 31.0 months and 30.0% in the non-lymph node jumping metastasis group (P 0.0001). Sex (P0. 027), age (P0. 008) and tumor differentiation (P0. 026) were associated with lymph node jumping metastasis. Tumor location (P0. 014) T stage (P0. 000) and skip metastasis (P0. 001) were independent prognostic factors of esophageal squamous cell carcinoma. Conclusion: jumping is one of the most common lymph node metastases in esophageal squamous cell carcinoma.
【學位授予單位】:濟南大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R735.1
本文編號:2159007
[Abstract]:Objective: to investigate the incidence of leaping lymph node metastasis in esophageal squamous cell carcinoma, to determine the risk factors of lymph node jumping metastasis and to evaluate the prognostic value of jump lymph node metastasis in thoracic esophageal squamous cell carcinoma. Methods: 113 patients underwent complete resection of esophageal carcinoma from January 1, 2011 to December 31, 2013 were collected. Results: the incidence of lymph node jump metastasis was 43.4% (49 / 113). The median survival time and 5-year survival rate were 18.0 months and 3.0 months in the lymph node jumping metastasis group, and 31.0 months and 30.0% in the non-lymph node jumping metastasis group (P 0.0001). Sex (P0. 027), age (P0. 008) and tumor differentiation (P0. 026) were associated with lymph node jumping metastasis. Tumor location (P0. 014) T stage (P0. 000) and skip metastasis (P0. 001) were independent prognostic factors of esophageal squamous cell carcinoma. Conclusion: jumping is one of the most common lymph node metastases in esophageal squamous cell carcinoma.
【學位授予單位】:濟南大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R735.1
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相關期刊論文 前3條
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,本文編號:2159007
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