術(shù)后吲哚菁綠15min滯留率聯(lián)合標(biāo)準(zhǔn)殘肝體積對肝細(xì)胞癌術(shù)后肝功能不全的預(yù)測價(jià)值
[Abstract]:Objective: to investigate the predictive value of indocyanine green 15 min retention rate (indocyanine green retention rate at 15 minutes ICG R15) combined with standard residual liver volume (standard remnant liver volumette SRLV) for postoperative liver dysfunction in hepatocellular carcinoma (HCC). Methods: the clinical data of 61 patients with hepatocellular carcinoma undergoing partial hepatectomy in Xiangya Hospital of Central South University from January 2015 to February 2016 were retrospectively studied. The patients were divided into two groups: good liver function group (nf40) and liver insufficiency group (nnn21). The risk factors of postoperative hepatic insufficiency were screened by single factor analysis, and the independent risk factors of postoperative hepatic insufficiency were screened by regression analysis and the regression equation was established. The value of single independent risk factor and combined independent risk factor in the diagnosis of postoperative liver insufficiency was analyzed by using (receiver operating characteristics curve. Results there were 21 cases of postoperative liver insufficiency in 61 cases of operation. The incidence of liver insufficiency was 34. 4%. The time of operation, the time of hepatic hilus occlusion, the volume of tumor were found in the group of good liver function and the group of liver insufficiency after operation. There was no significant difference in the volume of liver after resection (P0.05), but in postoperative ICG R15, the volume of intraoperative bleeding and SRLV were significantly different (P0.05). Postoperative ICG R 15, intraoperative bleeding and SRLV were risk factors for postoperative liver dysfunction. Regression analysis showed that postoperative ICG R15 and SRLV were independent risk factors for postoperative hepatic insufficiency. The regression equation was logit (P) 1.277 0.140 脳 ICG R15 5.125 脳 SRLV. The area under the ROC curve of ICG R15 combined with SRLV was larger than that of the single ICG R15 and SRLV ROC curve after operation, which was 0.713 and 0.681respectively. Conclusion: ICG R15 and SRLV are independent risk factors for postoperative liver dysfunction on the third day after operation. Its diagnostic value may be superior to that of ICG R15 and SRLV on the third day after operation.
【作者單位】: 中南大學(xué)湘雅醫(yī)院普通外科;
【基金】:湖南省衛(wèi)生與計(jì)劃生育委員會科研項(xiàng)目(B2016101)~~
【分類號】:R735.7
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