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腹腔鏡和開腹手術(shù)治療中國(guó)老年宮頸癌療效的Meta分析

發(fā)布時(shí)間:2018-07-27 16:38
【摘要】:目的比較腹腔鏡與開腹手術(shù)治療中國(guó)老年宮頸癌的療效。方法計(jì)算機(jī)檢索中國(guó)生物醫(yī)學(xué)文摘數(shù)據(jù)庫(kù)(CBM)、萬(wàn)方全文數(shù)據(jù)庫(kù)(wanfangdata)、中國(guó)知網(wǎng)全文數(shù)據(jù)庫(kù)(CNKI)、維普中文期刊數(shù)據(jù)庫(kù)(VIP)和Pub Med,根據(jù)入選標(biāo)準(zhǔn)篩選文獻(xiàn)。從文獻(xiàn)提取數(shù)據(jù),采用Rev Man 5.2.9軟件進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果最終納入符合標(biāo)準(zhǔn)的文獻(xiàn)10篇,均為臨床對(duì)照研究(CCT),無(wú)隨機(jī)對(duì)照研究(RCT)。腹腔鏡手術(shù)組與開腹手術(shù)組患者年齡、體重、腫瘤分期等基本特征無(wú)明顯差異。與開腹手術(shù)相比,腹腔鏡手術(shù)組手術(shù)時(shí)間長(zhǎng)(MD=32.60,95%CI:5.65~59.55,P=0.020),術(shù)中失血量少(MD=-94.01,95%CI:-130.65~-57.37,P=0.000),清除淋巴結(jié)數(shù)量少(MD=1.69,95%CI:0.67~2.72,P=0.001),術(shù)后排氣時(shí)間早(MD=-17.09,95%CI:-21.19~-12.98,P=0.000),住院時(shí)間短(MD=-4.30,95%CI:-5.57~-3.02,P=0.000),差異有統(tǒng)計(jì)學(xué)意義。而術(shù)后留置尿管時(shí)間(MD=-0.67,95%CI:-1.92~0.58,P=0.290)、手術(shù)并發(fā)癥發(fā)生率(OR^=0.62,95%CI:0.27~1.42,P=0.260),差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論腹腔鏡手術(shù)具有創(chuàng)傷小、恢復(fù)快等優(yōu)勢(shì),并不增加手術(shù)并發(fā)癥發(fā)生率,是治療中國(guó)老年宮頸癌的理想術(shù)式。
[Abstract]:Objective to compare the efficacy of laparoscopy and laparotomy in the treatment of elderly cervical cancer in China. Methods the Chinese biomedical abstract database (CBM), Wanfang full-text database (wanfangdata), (CNKI), Weipu Chinese periodical database (VIP) and Pub Medwere searched by computer and the literature was screened according to the selected criteria. The data were extracted from the literature and analyzed statistically by Rev Man 5.2.9 software. Results Ten articles were included in the standard, all of which were clinical controlled study, (CCT), no randomized controlled study, (RCT). There was no significant difference in age, weight and tumor stage between laparoscopy group and open operation group. 涓庡紑鑵規(guī)墜鏈浉姣,

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