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胃癌術后肺部并發(fā)癥相關危險因素分析

發(fā)布時間:2018-07-27 12:46
【摘要】:目的比較胃癌術后發(fā)生肺部并發(fā)癥病人與無并發(fā)癥病人間臨床病理特征,并分析胃癌術后肺部并發(fā)癥發(fā)生的危險因素。方法回顧性分析2012年1月至2015年12月四川大學華西醫(yī)院胃腸外科收治的719例胃癌手術病人臨床資料。排除殘胃癌、術前接受化療以及無肺部并發(fā)癥但合并其他并發(fā)癥病例后,分為肺部并發(fā)癥組(103例)與無并發(fā)癥組(616例)。結果肺部并發(fā)癥組病人術后住院時間較無并發(fā)癥組延長[(13.5±7.0)d vs.(10.7±3.1)d,P0.001],其余指標組間差異無統計學意義(P0.05)。單因素分析顯示,年齡(P=0.018)、肺部疾病史(P0.001)、術前肺功能[1 s用力呼氣量與用力肺活量比值(FEV1/FVC),P=0.002]、血紅蛋白(P=0.004)、術中出血(P=0.042)以及手術時間(P=0.048)與肺部并發(fā)癥發(fā)生相關;多因素分析發(fā)現,肺部疾病史(P0.001)、術前肺功能(P=0.032)以及血紅蛋白(P=0.004)為影響胃癌術后肺部并發(fā)癥發(fā)生的獨立危險因素。結論對于BMI≥25、合并肺部基礎疾病、FEV1/FVC60、血紅蛋白90 g/L的胃癌病人,應注意采取必要措施以減少術后肺部并發(fā)癥發(fā)生。
[Abstract]:Objective to compare the clinicopathological features of lung complications after gastric cancer operation and to analyze the risk factors of lung complications after gastric cancer surgery. Methods from January 2012 to December 2015, 719 patients with gastric cancer underwent gastrointestinal surgery in Huaxi Hospital of Sichuan University were retrospectively analyzed. After exclusion of gastric stump gastric cancer, chemotherapy before operation and without pulmonary complications but complicated with other complications, the patients were divided into pulmonary complication group (n = 103) and non-complication group (n = 616). Results the postoperative hospitalization time of pulmonary complication group was longer than that of no complication group [(13.5 鹵7.0) d vs. (10.7 鹵3.1) dP0.001], and there was no significant difference between other groups (P0.05). Univariate analysis showed that age (P0. 018), history of pulmonary disease (P0. 001), preoperative pulmonary function [1 s forced expiratory volume to forced vital capacity (FEV1/FVC) / P0. 002], hemoglobin (P0. 004), intraoperative hemorrhage (P0. 042) and operative time (P0. 048) were associated with pulmonary complications. Pulmonary disease history (P0.001), preoperative pulmonary function (P0. 032) and hemoglobin (P0. 004) were independent risk factors for pulmonary complications after gastric cancer surgery. Conclusion for gastric cancer patients with BMI 鈮,

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