本文選題：注射用益氣復(fù)脈 + 肺癌��； 參考：《中國現(xiàn)代醫(yī)學(xué)雜志》2017年06期

【摘要】：目的探討注射用益氣復(fù)脈(凍干)對(duì)中、晚期肺癌患者免疫功能和生存質(zhì)量的影響。方法選取2013年9月-2014年8月在該院經(jīng)組織病理學(xué)或細(xì)胞學(xué)確診為中、晚期肺癌并化療的患者63例為對(duì)照組;選擇2015年1月-2015年12月該院同類患者67例為觀察組。兩組患者給予相同的化療方案,輔助健康指導(dǎo)、營養(yǎng)支持、心理及康復(fù)鍛煉指導(dǎo),并給予止痛、止嘔等治療。觀察組在對(duì)照組的基礎(chǔ)上加用注射用益氣復(fù)脈。6個(gè)療程后比較兩組的免疫功能血液學(xué)指標(biāo)、生存質(zhì)量、卡氏評(píng)分、療效及不良反應(yīng)。結(jié)果觀察組可降低C-反應(yīng)蛋白和白細(xì)胞的數(shù)量,增加NKT細(xì)胞活性,增加T細(xì)胞亞群中CD3~+、CD4~+及CD4/CD8~+的比例,增強(qiáng)機(jī)體的免疫功能。治療前兩組患者的生存質(zhì)量評(píng)分差異無統(tǒng)計(jì)學(xué)意義,治療后兩組患者的生存質(zhì)量均提高。觀察組患者在認(rèn)知功能和經(jīng)濟(jì)困難方面與對(duì)照組患者改善程度一致,在其他維度方面優(yōu)于對(duì)照組。治療后觀察組患者卡氏評(píng)分與對(duì)照組比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組患者顯效率為95.52%,對(duì)照組為60.32%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組白細(xì)胞計(jì)數(shù)下降、血小板計(jì)數(shù)下降、血紅蛋白下降、肝功能異常、腎功能異常比例比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論注射用益氣復(fù)脈不僅可提高機(jī)體的免疫功能,而且可減少不良反應(yīng)的發(fā)生,提高患者生存質(zhì)量。
[Abstract]:Objective to investigate the effect of Yiqi Fumai (lyophilized) for injection on immune function and quality of life in patients with middle and advanced lung cancer. Methods Sixty-three patients with advanced lung cancer combined with chemotherapy were selected as control group from September 2013 to August 2014, and 67 patients from January 2015 to December 2015 were selected as observation group. The two groups were given the same chemotherapy regimen, supplementary health guidance, nutritional support, psychological and rehabilitation exercise guidance, pain relief, nausea and other treatment. After 6 courses of treatment, the immune function hematological indexes, quality of life, Karschoff score, curative effect and adverse reactions were compared between the two groups. Results the observation group could decrease the number of C-reactive protein and leukocytes, increase the activity of NKT cells, increase the proportion of CD3 ~ + CD4 ~ and CD4 ~-/ -CD8 ~ in T cell subsets, and enhance the immune function of the body. There was no significant difference in quality of life score between the two groups before treatment. The improvement of cognitive function and economic difficulty in the observation group was consistent with that in the control group, and was superior to the control group in other dimensions. After treatment, the observation group patients compared with the control group, the difference was statistically significant (P0.05). The effective rate of observation group was 95.52 and that of control group was 60.32, the difference was statistically significant (P0.05). The proportion of leukocyte count, platelet count, hemoglobin, liver function abnormality and renal function abnormality in the observation group were significantly lower than those in the control group (P0.05). Conclusion invigorating qi and tonifying veins for injection can not only improve the immune function, but also reduce the occurrence of adverse reactions and improve the quality of life of the patients.
【作者單位】： 青海大學(xué)附屬醫(yī)院中西醫(yī)結(jié)合科;
【基金】：青海大學(xué)附屬醫(yī)院中青年科研基金(No:ASRF-2014-03)
【分類號(hào)】：R734.2

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 閆琰;鄢丹;陳龍虎;張萍;任永申;馮雪;肖小河;;注射用益氣復(fù)脈(凍干)快速檢測(cè)分析方法研究[J];解放軍藥學(xué)學(xué)報(bào);2012年01期

2 馮琛;;注射用益氣復(fù)脈(凍干)治療冠心病慢性心力衰竭的臨床觀察[J];光明中醫(yī);2013年08期

3 于洪;益氣復(fù)脈湯治療心律失常56例[J];新中醫(yī);1996年S1期

4 呂芳;葉正良;李德坤;周大錚;;加熱時(shí)間對(duì)注射用益氣復(fù)脈(凍干)藥液中不同成分的影響研究[J];陜西中醫(yī);2012年10期

5 許軼蘭;益氣復(fù)脈湯治療中老年心律失常30例觀察[J];中原醫(yī)刊;1995年04期

6 楊昌林;劉召紅;;注射用益氣復(fù)脈(凍干)治療老年冠心病慢性心力衰竭臨床研究[J];實(shí)用老年醫(yī)學(xué);2014年07期

7 王敏;;益氣復(fù)脈注射液治療缺血性心肌病心衰患者臨床療效[J];當(dāng)代醫(yī)學(xué);2010年27期

8 吳漢卿,劉艷娟;益氣復(fù)脈湯治療心律失常臨床療效分析[J];湖北中醫(yī)雜志;1997年01期

9 楊穎;姜濤;王鳳;許蔚;周亞濱;;注射用益氣復(fù)脈(凍干)治療冠心病心力衰竭(氣陰兩虛證)60例臨床研究[J];中醫(yī)藥學(xué)報(bào);2012年04期

10 張立峰;韓曉萍;郭全興;葉正良;;近紅外光譜技術(shù)在注射用益氣復(fù)脈定性分析中的應(yīng)用價(jià)值[J];求醫(yī)問藥(下半月);2012年06期

相關(guān)會(huì)議論文 前4條

1 宋生有;傅俊曾;刑璐;郭婷婷;姜民;白鋼;羅國安;;液質(zhì)聯(lián)用技術(shù)在注射用益氣復(fù)脈(凍干)紅參成分鑒定中的應(yīng)用[A];第十屆全國藥用植物及植物藥學(xué)術(shù)研討會(huì)論文摘要集[C];2011年

2 王志偉;高鈞;胡靖;孫靜;;動(dòng)態(tài)濁度法測(cè)定益氣復(fù)脈(凍干)中的細(xì)菌內(nèi)毒素的含量[A];2010年中國藥學(xué)大會(huì)暨第十屆中國藥師周論文集[C];2010年

3 胡金芳;馮s，

本文編號(hào)：2091172