本文選題：內(nèi)鏡下黏膜剝離術(shù) + 黏膜下隧道　； 參考：《吉林大學(xué)》2016年碩士論文

【摘要】：背景:食管壁不同層次可以發(fā)生不同種類的良性腫瘤。此類腫瘤通常不引起癥狀,并且生長緩慢,常常由體檢是行食管影像學(xué)檢查或者內(nèi)鏡檢查發(fā)現(xiàn)。最常見的食管良性腫瘤是平滑肌瘤。內(nèi)鏡下治療方式逐步發(fā)脹,從簡單的活檢病理到應(yīng)用圈套器直接切除,再到內(nèi)鏡下黏膜切除術(shù)(EMR)。目前研究發(fā)現(xiàn)EMR仍存在一定局限性,例如腫瘤殘留及腫瘤再發(fā)。目前,幾項研究表明內(nèi)鏡下黏膜下隧道技術(shù)可以應(yīng)用于上皮下腫瘤治療。內(nèi)鏡下黏膜下隧道切除術(shù)(STER)可以安全有效的切除起源于上消化道固有肌層腫物(MP)。目的:本研究目的在于評價內(nèi)鏡下隧道技術(shù)治療食管固有肌層腫物的臨床價值,對比食管固有肌層腫物和胃內(nèi)固有肌層腫物治療中的異同。類型單中心回顧性研究。研究單位及時間吉林長春吉林大學(xué)第一醫(yī)院內(nèi)鏡中心,2014年1月-2016年1月。方法:對比研究22名上消化道固有肌層來源SMT患者應(yīng)用STER技術(shù)治療效果。結(jié)果:患者平均年齡是52.32歲(35-68歲)。男女比例為1:1.完整切除率為82%。18處病變整塊切除。病理結(jié)果為平滑肌瘤(10/22)和間質(zhì)瘤(9/22)。結(jié)論:STER治療SMT的整塊切除率和完整切除率較高,應(yīng)用軟式內(nèi)鏡治療消化道黏膜下腫瘤技術(shù)可以廣泛推廣。內(nèi)鏡下隧道技術(shù)治療胃內(nèi)黏膜下腫瘤難度較食管內(nèi)黏膜下腫瘤的難度高,但是在胃內(nèi)進(jìn)行隧道治療并不增加手術(shù)相關(guān)不良事件。隧道技術(shù)治療消化道黏膜下腫瘤具有較高的一塊切除率,在軟式內(nèi)鏡下進(jìn)行,此項技術(shù)被廣泛接受。STER作為新的內(nèi)鏡下切除技術(shù)治療食管固有肌層起源的腫瘤是可行的、安全的、有效的方法。應(yīng)用STER技術(shù)切除食管固有肌層起源腫瘤可以完好保存食管黏膜層,可以減少全層切除伴有的感染等其他并發(fā)癥。
[Abstract]:Background: various types of benign tumors may occur at different levels of the esophageal wall. These tumors are usually asymptomatic and slow to grow, often detected by a physical examination of esophagus imaging or endoscopy. The most common benign tumor of the esophagus is leiomyoma. Endoscopic dilatation, from simple biopsy and pathology to direct resection with trap, to endoscopic mucosal resection (EMR). Current studies have found that EMR still has some limitations, such as tumor residues and tumor recurrence. Currently, several studies have shown that endoscopic submucosal tunneling can be used in the treatment of subepithelial tumors. Endoscopic submucosal tunnel resection (star) can be performed safely and effectively from the superior digestive tract propria myomegaly (MP). Objective: to evaluate the clinical value of endoscopic tunnel technique in the treatment of esophageal muscular lamina propria. Type single center retrospective study. Research Unit and time Endoscopic Center, first Hospital of Jilin University, Changchun, Jilin Province, January 2014-January 2016. Methods: 22 patients with SMT derived from the superior digestive tract were studied. Results: the average age of the patients was 52.32 years (35-68 years). The ratio of men to women is 1: 1. The complete resection rate was 82.18 lesions. Pathological findings were leiomyoma (10 / 22) and stromal tumors (9 / 22). Conclusion the mass resection rate and complete resection rate of SMT treated by weight ster are higher. The soft endoscopy can be widely used in the treatment of submucosal tumors of digestive tract. Endoscopic tunneling is more difficult to treat submucous tumor in stomach than that of submucous tumor in esophagus, but tunneling in stomach does not increase the adverse events associated with operation. The tunneling technique for the treatment of submucosal tumors of digestive tract has a high removal rate and is performed under soft endoscopy. This technique is widely accepted as a new endoscopic resection technique for the treatment of neoplasms originating from the lamina propria muscularis of the esophagus, which is feasible and safe. An effective method. The resection of the origin tumor of the lamina propria muscularis of the esophagus by the technique of fer can preserve the esophageal mucosal layer perfectly and reduce the complications such as infection and other complications associated with the removal of the whole layer of esophagus.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R735.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 Yu Zhang;Li-Ping Ye;Xin-Li Mao;;Endoscopic treatments for small gastric subepithelial tumors originating from muscularis propria layer[J];World Journal of Gastroenterology;2015年32期

2 Hyun Ho Choi;Jin Su Kim;Dae Young Cheung;Young-Seok Cho;;Which endoscopic treatment is the best for small rectal carcinoid tumors?[J];World Journal of Gastrointestinal Endoscopy;2013年10期

3 Noriko Nishiyama;Hirohito Mori;Hideki Kobara;Kazi Rafiq;Shintarou Fujihara;Mitsuyoshi Kobayashi;Makoto Oryu;Tsutomu Masaki;;Efficacy and safety of over-the-scope clip: Including complications after endoscopic submucosal dissection[J];World Journal of Gastroenterology;2013年18期

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本文編號：2066745