本文選題：肺癌 + 術(shù)后并發(fā)癥�。� 參考：《新鄉(xiāng)醫(yī)學(xué)院》2015年碩士論文

【摘要】：目的：1.探討肺癌術(shù)后出現(xiàn)并發(fā)癥的危險(xiǎn)因素,制定合理有效的預(yù)防措施。2.了解肺癌患者手術(shù)前后生活質(zhì)量及其變化情況。方法：回顧性分析114例肺癌手術(shù)治療的患者臨床資料,其中36例出現(xiàn)術(shù)后并發(fā)癥,對(duì)其危險(xiǎn)因素做出單因素卡方檢驗(yàn)和多因素logistic回歸分析。采用QLQ-C30對(duì)患者QOL進(jìn)行問(wèn)卷調(diào)查。調(diào)查分別于術(shù)前3天及術(shù)后4周、12周進(jìn)行。結(jié)果：1.114例肺癌術(shù)后出現(xiàn)并發(fā)癥的有36(31.58%)例,危險(xiǎn)因素單因素分析結(jié)果顯示年齡、冠心病、糖尿病、慢性阻塞性肺部疾病、吸煙史、煙齡、于術(shù)持續(xù)時(shí)間、FEV%有統(tǒng)計(jì)學(xué)意義(P0.05)。危險(xiǎn)因素多因素Logistic回歸分析結(jié)果顯示年齡(OR=13.824,95%CI 2.637-71.500)、冠心病(OR=10.800,95%CI2.309～50.510)、慢性阻塞性肺部疾病(OR=4.267,95%CI 1.060-17.183)、煙齡(OR=8.517,95%CI2.457-29.523)是并發(fā)癥的危險(xiǎn)因素(P0.05)。2.肺癌術(shù)后生活質(zhì)量較低,術(shù)后3個(gè)月基本恢復(fù)術(shù)前水平。角色功能下降幅度最為明顯,術(shù)后3個(gè)月除社會(huì)功能外,其他各功能領(lǐng)域及總健康狀況均有所上升,與術(shù)前水平接近。對(duì)于疼痛、疲倦等癥狀指標(biāo),術(shù)后1個(gè)月均有不同程度的上升,術(shù)后3個(gè)月逐漸恢復(fù)。101例患者手術(shù)前生命質(zhì)量在認(rèn)知功能領(lǐng)域得分最高,為72.77±15.04,在功能領(lǐng)域,手術(shù)后1個(gè)月較術(shù)前均有所降低,術(shù)后3個(gè)月有所恢復(fù),不同時(shí)間段肺癌患者生活質(zhì)量功能領(lǐng)域比較均具有統(tǒng)計(jì)學(xué)意義(P0.05)；在癥狀領(lǐng)域,惡心嘔吐及腹瀉癥狀術(shù)前得分最低,分別為8.75±14.26、9.57±15.87；術(shù)后有所升高；除氣促、便秘、腹瀉三個(gè)時(shí)間段進(jìn)行比較無(wú)統(tǒng)計(jì)學(xué)意義外,其他癥狀(疲倦、惡心嘔吐、失眠、疼痛、食欲喪失)均具有統(tǒng)計(jì)學(xué)意義。結(jié)論：1.肺癌手術(shù)患者術(shù)后出現(xiàn)并發(fā)癥的發(fā)生率很高,年齡、煙齡、冠心病和慢性阻塞性肺部疾病是并發(fā)癥的高危因素。2.并發(fā)癥嚴(yán)重降低病人的生活質(zhì)量,應(yīng)該針對(duì)這些危險(xiǎn)因素找到相應(yīng)的預(yù)防措施,盡可能降低風(fēng)險(xiǎn)。
[Abstract]:Purpose 1. To explore the risk factors of postoperative complications of lung cancer and to formulate reasonable and effective preventive measures. 2. Objective: to investigate the quality of life and its changes in patients with lung cancer before and after operation. Methods: the clinical data of 114 patients with lung cancer undergoing surgical treatment were retrospectively analyzed. Among them, 36 cases had postoperative complications. The risk factors were analyzed by single factor chi-square test and multivariate logistic regression analysis. QLQ-C 30 was used to investigate QOL. The investigation was conducted 3 days before operation and 12 weeks after operation. Results 36 (31.58%) cases of lung cancer had complications after operation. Age, coronary heart disease, diabetes, chronic obstructive pulmonary disease, smoking history, smoking age and FEV% were statistically significant (P0.05). Multivariate logistic regression analysis showed that age (OR 13.824 CI 2.637-71.500), coronary heart disease (OR 10.800), chronic obstructive pulmonary disease (OR 4.267 ~ 95CI 1.060-17.183), smoking age (OR8.51795CI2.457-29.523) were risk factors of complications (P0.05). The quality of life of lung cancer was lower after operation, and the preoperative level was basically restored 3 months after operation. The decrease of role function was the most obvious, except for social function, the other functional areas and the total health status were all increased in 3 months after operation, which were close to the preoperative level. For symptoms such as pain, fatigue and so on, there were different degrees of increase at one month after operation. The scores of life quality of 101 patients before operation were the highest (72.77 鹵15.04) in the field of cognitive function 3 months after operation, and gradually recovered at 3 months after operation, and the scores of QOL in cognitive function were the highest (72.77 鹵15.04). One month after surgery compared with the preoperative decreased, 3 months after the recovery, different time of lung cancer patients with quality of life functional areas were statistically significant (P0.05); in the symptom area, nausea and vomiting and diarrhea symptoms before the lowest score, There was no significant difference in other symptoms (fatigue, nausea and vomiting, insomnia, pain, loss of appetite) except for shortness of breath, constipation and diarrhea. Conclusion 1. The incidence of postoperative complications in patients with lung cancer is high. Age, coronary heart disease and chronic obstructive pulmonary disease are high risk factors for complications. The complication seriously reduces the patient's quality of life, should find the corresponding prevention measure to these risk factors, reduce the risk as far as possible.
【學(xué)位授予單位】：新鄉(xiāng)醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R734.2

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相關(guān)期刊論文 前5條

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本文編號(hào)：2050349