本文選題：單孔胸腔鏡 + 多孔胸腔鏡��； 參考：《昆明醫(yī)科大學(xué)》2017年碩士論文

【摘要】：[目的] 系統(tǒng)評價單孔胸腔鏡(single-incision thoracoscopic surgery,SITS)和多孔胸腔鏡在肺癌治療上的療效,評估單孔胸腔鏡的安全性和可行性。[方法]計(jì)算機(jī)檢索 PubMed, Cochrane Library,Springer Link 和 Science Direct等數(shù)據(jù)庫,收集單孔胸腔鏡和多孔胸腔鏡治療肺癌的隨機(jī)對照研究和非隨機(jī)研究,評估項(xiàng)目包括手術(shù)時間,術(shù)中出血量,胸管引流時間,術(shù)后住院日,淋巴結(jié)清掃個數(shù)和術(shù)后并發(fā)癥的發(fā)生率。檢索時限均為建庫至2016年12月30日,由兩位研究者獨(dú)立篩選文獻(xiàn),提取資料和評價納入研究的偏移風(fēng)險后,采用RevMan 5.0 (Cochrane Collaboration, Oxford,UK)和 STATA 11.2 軟件(StataCorp,College Station, Texas USA)來進(jìn)行統(tǒng)計(jì)分析。[結(jié)果]共納入11個研究,1314名病人。Meta分析結(jié)果顯示:與多孔胸腔鏡手術(shù)相比,單孔胸腔鏡術(shù)后住院時間更短[WMD=0.50d,95%CI(-0.87,-0.13),p=0.008]和術(shù)后并發(fā)癥的發(fā)生率更低[OR=0.64,95%CI(0.45,0.90),p=0.009],p=0.009],但兩組在手術(shù)時間[WMD=9.39min,95%CI(-7.48,26.26),p=0.28],術(shù)中出血量[WMD=-7.700mL,95%CI(-20.02,4.62),p=0.22],胸腔引流時間[WMD=-0.72d,95%CI(-1.44,0.002),p=0.051]和淋巴結(jié)清掃個數(shù)[WMD=-0.45,95%CI(-1.03,0.13),p=0.13]方面,差異無統(tǒng)計(jì)學(xué)意義。[結(jié)論]單孔胸腔鏡在肺癌外科治療上比起多孔胸腔鏡在縮短住院時間和降低術(shù)后并發(fā)癥的發(fā)生更有優(yōu)勢,單孔胸腔鏡可被視為在肺癌外科治療中代替多孔胸腔鏡一種安全可行的方法。
[Abstract]:[objective] to evaluate the efficacy and safety of single-hole thoracoscopic thoracoscopy (SITSs) and porous thoracoscopy in the treatment of lung cancer, and to evaluate the safety and feasibility of single-hole thoracoscopy. [methods] PubMed, Cochrane LibrarySpringer Link and Science Direct databases were searched by computer to collect randomized controlled and non-randomized studies for the treatment of lung cancer by single hole thoracoscopy and porous thoracoscopy. The evaluation items included operative time and intraoperative bleeding. Time of thoracic drainage, length of hospitalization, number of lymph node dissection and incidence of postoperative complications. The retrieval time is from the date of establishment until December 30, 2016. After the two researchers independently sifted the literature, extracted the data and evaluated the migration risk in the study, the statistical analysis was carried out by RevMan 5.0 Cochrane collaboration (Oxford UK) and StataCorpton College Stationation, Texas USA. the STATA 11.2 software was used to carry out the statistical analysis. [results] A meta-analysis of 1314 patients in 11 studies showed that compared with thoracoscopic surgery, 鍗曞瓟鑳歌厰闀滄湳鍚庝綇闄㈡椂闂存洿鐭璠WMD=0.50d,95%CI(-0.87,-0.13),p=0.008]鍜屾湳鍚庡茍鍙戠棁鐨勫彂鐢熺巼鏇翠綆[OR=0.64,95%CI(0.45,0.90),p=0.009],浣嗕袱緇勫湪鎵嬫湳鏃墮棿[WMD=9.39min,95%CI(-7.48,26.26),p=0.28],鏈腑鍑鴻閲廩WMD=-7.700mL,95%CI(-20.02,4.62),p=0.22],鑳歌厰寮曟祦鏃墮棿[WMD=-0.72d,95%CI(-1.44,0.002),p=0.051]鍜屾穻宸寸粨娓呮壂涓暟[WMD=-0.45,95%CI(-1.03,0.13),p=0.13]鏂歸潰,宸紓鏃犵粺璁″鎰忎箟. [conclusion] Single-hole thoracoscopy is superior to porous thoracoscopy in shortening hospital stay and reducing postoperative complications in the surgical treatment of lung cancer. Single-hole thoracoscopy can be regarded as a safe and feasible method to replace porous thoracoscopy in the surgical treatment of lung cancer.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R734.2

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