MRI和術(shù)前組織學(xué)聯(lián)合對(duì)子宮內(nèi)膜癌淋巴結(jié)轉(zhuǎn)移高危因素的評(píng)估
發(fā)布時(shí)間:2018-06-04 15:23
本文選題:MRI + 術(shù)前組織學(xué); 參考:《山西醫(yī)科大學(xué)》2017年碩士論文
【摘要】:目的:探討MRI與術(shù)前組織學(xué)聯(lián)合對(duì)區(qū)分子宮內(nèi)膜癌高;虻臀A馨徒Y(jié)轉(zhuǎn)移的準(zhǔn)確性。方法:回顧性分析2013.11~2016.11于山西醫(yī)科大學(xué)第一醫(yī)院確診為子宮內(nèi)膜癌(Endometrial Cancer,EC)行手術(shù)治療的134例患者。將101例行全面分期術(shù)患者的術(shù)前診刮病理組織學(xué)結(jié)果(分級(jí)和分型)及盆腔MRI的結(jié)果(肌層浸潤深度及淋巴結(jié)腫大)與最終病理進(jìn)行比較。結(jié)果:MRI對(duì)宮頸受累和淋巴結(jié)(Lymph Node,LN)轉(zhuǎn)移有較高特異性(Specificity,SP)和陰性預(yù)測值(Negative predictive value,NPV),術(shù)前組織學(xué)對(duì)G3和Ⅱ型內(nèi)膜癌也有較高的SP和NPV。術(shù)前組織學(xué)和MRI聯(lián)合識(shí)別高;颊呔哂休^好的診斷價(jià)值(AUC=0.814),與術(shù)后病理也有良好的一致性(Kappa值=0.623)。經(jīng)MRI和術(shù)前組織學(xué)聯(lián)合評(píng)估均低危的39例患者,最終病理結(jié)果無盆腔或腹主動(dòng)脈旁LN轉(zhuǎn)移。結(jié)論:MRI和術(shù)前組織學(xué)對(duì)EC淋巴結(jié)轉(zhuǎn)移危險(xiǎn)因素的評(píng)估是有意義的。MRI和術(shù)前組織學(xué)可以較準(zhǔn)確的識(shí)別低;颊,從而避免不必要的淋巴結(jié)切除術(shù)及術(shù)后并發(fā)癥的發(fā)生。
[Abstract]:Objective: to evaluate the accuracy of MRI combined with preoperative histology in differentiating high risk or low risk lymph node metastasis from endometrial carcinoma. Methods: 134 cases of endometrial carcinoma diagnosed as Endometrial carcinoma (EC) in the first Hospital of Shanxi Medical University were analyzed retrospectively. The histopathological results (classification and classification) of preoperative curettage and the results of pelvic MRI (depth of myometrial invasion and lymphadenopathy) were compared with the final pathology. Results there was a high specificity and negative predictive value for cervical involvement and lymph node lymphatic lymph node metastasis. Preoperative histology was also associated with high SP and NPV in G3 and type 鈪,
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