本文選題：軟骨肉瘤 + 手術(shù)治療　； 參考：《山西醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:軟骨肉瘤是臨床工作中一種比較常見的惡性骨腫瘤,目前普遍認(rèn)為這種惡性腫瘤對放化療等輔助治療的敏感性比較差,因此其主要治療手段為手術(shù)切除。本研究回顧分析了2004年6月至2014年6月在我院經(jīng)X線、CT、MRI檢查及病理檢查診斷確診為軟骨肉瘤并接受手術(shù)的患者,一共34例,并探討影響患者術(shù)后復(fù)發(fā)的因素。方法:分析了2004年6月至2014年6月在我院經(jīng)輔助檢查及病理診斷確診為軟骨肉瘤并接受手術(shù)的病例。假定影響術(shù)后復(fù)發(fā)的因素為:年齡、性別、瘤體的大小、發(fā)病部位、病程長短、腫瘤細(xì)胞的組織學(xué)分級、術(shù)前術(shù)后是否接受放化療。術(shù)后按時、規(guī)律隨訪,了解病人術(shù)后局部的復(fù)發(fā)狀況。用SPSS19.0軟件對收集的數(shù)據(jù)進(jìn)項單因素分析,計算每組的c2和P值。結(jié)果:于2004年6月至2014年6月在我院經(jīng)X線、CT、MRI檢查及病理學(xué)檢查確診為軟骨肉瘤并接受了手術(shù)治療的病人一共有34例,平均隨訪時間為4年。其中男性軟骨肉瘤患者為20例,女性軟骨肉瘤患者為14例,患者的患病年齡為17~78歲,平均患病年齡為46歲;病程為3~14月,平均7月;腫瘤大小5cm3~1500cm3,平均550cm3。腫瘤生長于四肢骨及肩胛骨的患者有19例,生長于中軸骨的患者有15例。腫瘤細(xì)胞的組織分級為Ⅰ級、Ⅱ級和Ⅲ級的患者分別為19例、10例和5例,接受放化療的有6例,未接受放化療的有28例。其中瘤體大小、腫瘤細(xì)胞組織學(xué)分級與術(shù)后的復(fù)發(fā)率有關(guān)(P0.05),患者的年齡、性別、發(fā)病部位、病程長短、術(shù)前術(shù)后是否接受放化療與術(shù)后復(fù)發(fā)率在統(tǒng)計學(xué)上沒有明顯的相關(guān)性(P0.05)。結(jié)論:1.軟骨肉瘤瘤體的大小、腫瘤細(xì)胞的組織病理學(xué)分級可以影響軟骨肉瘤患者術(shù)后的復(fù)發(fā)率。2.年齡、性別、發(fā)病部位、病程長短、是否接受放化療在軟骨肉瘤患者術(shù)后復(fù)發(fā)率沒有統(tǒng)計學(xué)差異。
[Abstract]:Objective: chondrosarcoma is a common malignant bone tumor in clinical work. From June 2004 to June 2014, 34 cases of chondrosarcoma diagnosed and operated by X-ray CT MRI and pathological examination in our hospital were retrospectively analyzed, and the factors influencing the recurrence of the patients were discussed. Methods: the cases of chondrosarcoma diagnosed and operated in our hospital from June 2004 to June 2014 were analyzed. It is assumed that the factors influencing recurrence after operation are age, sex, size of tumor, location of disease, duration of disease, histological grade of tumor cells, whether or not to receive radiotherapy and chemotherapy before and after operation. Follow up regularly and on time after operation to understand the local recurrence of patients. The data were analyzed by single factor analysis with SPSS19.0 software, and the values of C2 and P in each group were calculated. Results: from June 2004 to June 2014, 34 cases of chondrosarcoma were diagnosed and treated by CT MRI and pathology in our hospital. The average follow-up time was 4 years. There were 20 cases of male chondrosarcoma and 14 cases of female chondrosarcoma. The age of the disease was 1778 years old, the average age was 46 years, the course of disease was 3 ~ 14 months, the average was 7 months, and the tumor size was 5 cm ~ 3 ~ 1 500 cm ~ 3 with an average of 550 cm ~ 3. There were 19 cases of tumor growing in the limbs and scapula, and 15 cases of the axial bone. The tumor cells were classified as grade 鈪，

本文編號：1970660