本文選題：子宮內(nèi)膜癌 + 保留生育功能��； 參考：《廣西醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:本文運(yùn)用Meta分析的方法,對年輕早期子宮內(nèi)膜癌患者應(yīng)用宮腔鏡保守性手術(shù)聯(lián)合孕激素治療的療效、治療后妊娠等相關(guān)問題進(jìn)行討論分析。方法:收集2000年1月至2017年3月之間發(fā)表的關(guān)于40歲以下早期子宮內(nèi)膜癌患者應(yīng)用宮腔鏡保守性手術(shù)聯(lián)合孕激素治療以保留生育功能的相關(guān)文獻(xiàn),嚴(yán)格按照納入標(biāo)準(zhǔn)選擇文獻(xiàn),納入原始的研究資料,提取資料及有效數(shù)據(jù),利用R軟件(R3.3.2)進(jìn)行單個(gè)樣本率的Meta分析。結(jié)果:共15篇文獻(xiàn)入選,203例患者參與研究。Meta分析結(jié)果示:宮腔鏡保守性手術(shù)聯(lián)合孕激素治療后的完全緩解率為89.40%,95%CI[0.8329-0.9346],復(fù)發(fā)率為10.90%,95%CI[0.0682-0.1741],總?cè)焉锫蕿?3.44%,95%CI[0.5572-0.7053],總分娩率為59.69%,95%CI[0.5262-0.6656]。結(jié)論:多數(shù)早期子宮內(nèi)膜癌患者應(yīng)用宮腔鏡保守性手術(shù)聯(lián)合孕激素治療可獲得完全緩解,并順利妊娠、分娩,部分患者存在復(fù)發(fā)或治療無效的情況,但及時(shí)接受傳統(tǒng)手術(shù)治療,仍能獲得良好預(yù)后。
[Abstract]:Objective: to analyze the effects of hysteroscopic conservative surgery combined with progesterone on the treatment of early endometrial carcinoma in young patients with early endometrial carcinoma by means of Meta analysis.Methods: from January 2000 to March 2017, the literature on hysteroscopic conservative surgery combined with progesterone therapy to preserve fertility function in patients with early endometrial carcinoma under 40 years old was collected and selected according to the inclusion criteria.The Meta analysis of single sample rate was carried out by using R software R3.3.2), which included the original research data, extracted the data and valid data.Results: the results of Meta-analysis showed that the complete remission rate of hysteroscopic conservative surgery combined with progesterone therapy was 89.400.95 CI [0.8329-0.9346], the recurrence rate was 10.90 ~ 95CI [0.0682-0.1741], the total pregnancy rate was 63.4495 CI [0.5572-0.7053], the total delivery rate was 59.699595 CI [0.5262-0.6656].Conclusion: most patients with early endometrial carcinoma can be treated with hysteroscopic conservative surgery combined with progesterone for complete remission, pregnancy, delivery, recurrence or ineffective treatment in some patients, but receive traditional surgical treatment in time.A good prognosis can still be obtained.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R737.33

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 楊斯鈉;劉，

本文編號：1766034