本文選題：肺癌化療　切入點：醫(yī)院感染　出處：《中國消毒學雜志》2017年02期

【摘要】：目的研究住院肺癌化療患者醫(yī)院感染病原學特征及相關(guān)危險因素,為有效防控提供科學依據(jù)。方法通過前瞻性研究方法,對某腫瘤醫(yī)院內(nèi)科住院肺癌化療患者醫(yī)院感染與感染病原菌特征進行觀察,分析相關(guān)危險因素。結(jié)果該醫(yī)院腫瘤內(nèi)科共納入肺癌化療患者1 530例,發(fā)生醫(yī)院感染56例,感染率3.66%。從56例感染患者送檢標本中共分離病原菌74株,其中革蘭陰性菌45株、革蘭陽性菌16株和真菌13株。除真菌之外,所分離的病原菌均普遍耐藥,尚未檢出耐碳青霉烯類和耐萬古霉素菌株。多因素分析顯示,住院時間≥14 d、化療周期≥2周和大量預防性使用抗菌藥物等構(gòu)成肺癌化療患者醫(yī)院感染的獨立危險因素。結(jié)論肺癌化療患者醫(yī)院感染病原菌以革蘭陰性菌為主,且耐藥情況嚴重,縮短化療周期和嚴格抗菌藥物使用為主要防控措施。
[Abstract]:Objective to study the etiological characteristics and related risk factors of nosocomial infection in lung cancer patients with chemotherapy, and to provide scientific basis for effective prevention and control.Methods the characteristics of nosocomial infection and pathogenic bacteria in lung cancer patients treated with chemotherapy in a tumor hospital were observed and the risk factors were analyzed.Results A total of 1 530 lung cancer patients were included in the department of oncology in this hospital, 56 cases of nosocomial infection occurred, and the infection rate was 3.66%.A total of 74 pathogenic bacteria were isolated from 56 infected patients, including 45 Gram-negative bacteria, 16 Gram-positive bacteria and 13 fungi.With the exception of fungi, the isolated pathogens were generally resistant to drugs, and no carbapenem resistant strains and vancomycin resistant strains were detected.Multivariate analysis showed that hospital stay 鈮，

本文編號：1724204