本文選題：四肢　切入點：缺血預(yù)處理　出處：《重慶醫(yī)學(xué)》2017年06期

【摘要】：目的探討遠(yuǎn)隔缺血預(yù)處理(RIPC)對全身麻醉下開胸手術(shù)患者單肺通氣(OLV)時肺損傷的影響。方法擇期行開胸食管癌根治術(shù)患者80例,采用隨機(jī)數(shù)字表法分為2組(n=40):對照組(C組)和肢體RIPC組(RIPC組)。于OLV即刻(T1)、30min(T2)、1h(T3)、2h(T4)時采集橈動脈血樣行血氣分析,計算氧合指數(shù)(OI)、呼吸指數(shù)(RI)和PaO2/PAO2,采用酶聯(lián)免疫吸附法測定血漿TNF-α、IL-1β和IL-10的水平,收集呼出氣冷凝液,測定pH值。結(jié)果與C組比較,RIPC組T2~T4時OI升高,RI降低,PaO2/PAO2升高,T3~T4時,血漿TNF-α和IL-1β水平降低,呼出氣冷凝液pH值升高,T4時血漿IL-10水平升高(P0.05)。結(jié)論 RIPC可抑制開胸手術(shù)患者OLV時的炎性反應(yīng),減輕氣道酸化,從而減輕肺損傷。
[Abstract]:Objective to investigate the effect of remote ischemic preconditioning (RIPC) on lung injury in patients undergoing open chest surgery under general anesthesia.Methods A total of 80 patients with esophageal carcinoma undergoing radical resection were randomly divided into two groups: control group (C group) and limb RIPC group (RIPC group).浜嶰LV鍗沖埢(T1),30min(T2),1h(T3),2h(T4)鏃墮噰闆嗘　鍔ㄨ剦琛，

本文編號：1712788