本文選題：副瘤性神經(jīng)系統(tǒng)綜合征　切入點：惡性腫瘤　出處：《重慶醫(yī)科大學(xué)學(xué)報》2017年06期 　論文類型：期刊論文

【摘要】：副瘤性神經(jīng)系統(tǒng)綜合征(paraneoplastic neurological syndromes,PNS)是一種與惡性腫瘤密切關(guān)聯(lián)的神經(jīng)系統(tǒng)疾病,通常要排除其他原因。由于神經(jīng)系統(tǒng)的每個層面均可受累,從而可導(dǎo)致神經(jīng)系統(tǒng)的各部位損害出現(xiàn)廣泛的神經(jīng)系統(tǒng)癥狀和體征。自從發(fā)現(xiàn)特異性抗神經(jīng)元胞核、胞漿及胞膜自身循環(huán)抗體后,對該病的認識及診斷得到很大提高,證實自身免疫作用導(dǎo)致PNS發(fā)生。本文就該病的臨床表現(xiàn)、臨床診斷標準、發(fā)病機制及癌腫與自身免疫的相關(guān)性作一闡述。
[Abstract]:Paraneoplastic neurological syndrome (PNS) is a nervous system disease closely associated with malignant tumors, usually excluding other causes. This may lead to extensive neurological symptoms and signs in various parts of the nervous system. Since the discovery of specific anti-neuronal nuclear, cytoplasmic and cytosolic autocirculatory antibodies, the recognition and diagnosis of the disease have been greatly improved. It is proved that autoimmune action leads to PNS. The clinical manifestation, clinical diagnostic criteria, pathogenesis and the correlation between autoimmunity and cancer are discussed in this paper.
【作者單位】： 蚌埠醫(yī)學(xué)院第一附屬醫(yī)院神經(jīng)內(nèi)科;
【分類號】：R73;R747.9
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本文編號：1623744