本文選題：體層攝影術(shù)　切入點(diǎn)：X線計(jì)算機(jī)　出處：《臨床放射學(xué)雜志》2017年06期 　論文類型：期刊論文

【摘要】：目的探討CT能譜成像在胃癌與高度侵襲危險(xiǎn)性胃間質(zhì)瘤鑒別診斷中的應(yīng)用價(jià)值。方法回顧性分析經(jīng)手術(shù)病理證實(shí)并行CT能譜成像雙期增強(qiáng)掃描的30例胃癌及24例高度侵襲危險(xiǎn)性胃間質(zhì)瘤患者的影像資料,通過GSI Viewer分析軟件獲得病灶能譜曲線,分別計(jì)算40~70、70~140、40~140 ke V各能量區(qū)間的能譜曲線斜率。同時(shí)測(cè)量病灶的碘濃度(IC)、水濃度(WC),并計(jì)算標(biāo)準(zhǔn)化后的碘濃度(NIC)(病灶碘濃度與同層腹主動(dòng)脈碘濃度的比值)。結(jié)果采用獨(dú)立樣本t檢驗(yàn)進(jìn)行統(tǒng)計(jì)學(xué)分析,比較兩組間的能譜參數(shù)差異。結(jié)果靜脈期,胃癌組的IC(23.78±6.85)(100μg/mL)、NIC(0.54±0.15)均大于相應(yīng)期相高度侵襲危險(xiǎn)性胃間質(zhì)瘤組(16.87±2.67)(100μg/m L)、(0.34±0.04)(P0.05),兩組的WC差別無統(tǒng)計(jì)學(xué)意義(P0.05);靜脈期胃癌組在40~70、70~140、40~140 ke V各能量區(qū)間的能譜曲線斜率(4.64±1.28、0.68±0.21、1.87±0.53)均大于相應(yīng)期相胃間質(zhì)瘤組(3.35±0.52、0.48±0.11、1.33±0.20)(P0.05)。動(dòng)脈期胃癌組與高度侵襲危險(xiǎn)性胃間質(zhì)瘤組的IC、NIC、WC及各能量區(qū)間的能譜曲線斜率差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論胃癌和高度侵襲危險(xiǎn)性胃間質(zhì)瘤具有不同的能譜成像參數(shù),可以借助能譜參數(shù)對(duì)二者進(jìn)行鑒別診斷。
[Abstract]:Objective to evaluate the value of CT energy dispersive imaging in the differential diagnosis of gastric cancer from highly invasive gastric stromal tumors. Methods 30 cases of gastric carcinoma and 24 cases of gastric carcinoma with dual-phase enhanced CT scan proved by surgery and pathology were analyzed retrospectively. Imaging data of patients with highly invasive gastric stromal tumors, The energy spectrum curves of the lesions were obtained by GSI Viewer software. The slope of the energy spectrum curve of each energy range of 4070 / 70 / 140 / 140 ~ 140ke V was calculated respectively. The iodine concentration of the lesion was measured, and the water concentration and the iodine concentration were calculated. The ratio of the iodine concentration of the lesion to the iodine concentration of the same layer of the abdominal aorta was calculated by using the method of measuring the ratio of the iodine concentration of the lesion to the iodine concentration of the same layer of the abdominal aorta. Independent sample t-test was used for statistical analysis. The differences of energy spectrum parameters between the two groups were compared. The IC(23.78 鹵6.85 ~ 100 渭 g 路mL ~ (-1) Nic _ (0.54 鹵0.15) in gastric cancer group was higher than that in the corresponding phase high risk gastric stromal tumor group (16.87 鹵2.67 ~ 100 渭 g 路mL ~ (-1)), 0.34 鹵0.04 (P _ (0.05)). There was no significant difference in WC between the two groups (P _ (0.05)), and the energy spectrum curve slope was 4.64 鹵1.280.68 鹵0.21 鹵0.53 鹵0.53 in the vein phase gastric cancer group. In stromal tumor group, there was no significant difference in ICNICWC and energy spectrum slope between arterial gastric cancer group and high invasive risk gastric stromal tumor group (P 0.05). Conclusion gastric carcinoma and highly invasive stromal tumor have different EDS imaging parameters. Energy spectrum parameters can be used to differentiate the two.
【作者單位】： 鄭州大學(xué)第一附屬醫(yī)院放射科;
【基金】：國(guó)家自然科學(xué)基金面上項(xiàng)目(編號(hào):81271573)
【分類號(hào)】：R730.44;R735.2

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