本文關(guān)鍵詞： 胃腸道間質(zhì)瘤 腹腔鏡手術(shù) 開腹手術(shù) Meta分析　出處：《南昌大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的本Meta分析從詢證醫(yī)學(xué)的角度運(yùn)用數(shù)據(jù)分析的方法對(duì)胃腸道間質(zhì)瘤的手術(shù)方式進(jìn)行對(duì)比,評(píng)價(jià)在腹腔鏡輔助下行胃腸道間質(zhì)瘤切除術(shù)(LAP)和開腹手術(shù)(OPEN)在胃腸道間質(zhì)瘤治療中的安全性、有效性、微創(chuàng)性。方法通過南昌大學(xué)圖書館計(jì)算機(jī)檢索Pubmed、Elsevier、SPRINGER、The Cochrane Library等數(shù)據(jù)庫。收集2004年1月至2014年3月發(fā)表的有關(guān)腹腔鏡輔助胃腸道間質(zhì)瘤切除術(shù)(LAP)和開腹胃腸道間質(zhì)瘤切除術(shù)(OPEN)對(duì)比的英文文獻(xiàn),先按照納入和排除的標(biāo)準(zhǔn)篩選文獻(xiàn)、然后提取資料并對(duì)文獻(xiàn)進(jìn)行質(zhì)量評(píng)價(jià),最后利用Review Manager 5.2軟件進(jìn)行Meta分析。結(jié)果本Meta分析共納入12篇文獻(xiàn)(共有719例病人),其中LAP組345例,OPEN組374例。薈萃分析結(jié)果顯示,與OPEN相比,LAP在術(shù)后排氣時(shí)間、進(jìn)流質(zhì)時(shí)間和住院時(shí)間方面更短(P=0.04、P0.00001、P0.00001),在術(shù)后并發(fā)癥發(fā)生率及復(fù)發(fā)率方面更低(P=0.0004、0.005),而在手術(shù)時(shí)間、術(shù)中出血量方面二者差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論LAP與OPEN對(duì)比在加快術(shù)后恢復(fù)、減少并發(fā)癥、降低復(fù)發(fā)率上體現(xiàn)了明顯的微創(chuàng)優(yōu)勢。所以LAP在技術(shù)上是可行的,具有良好的安全性,并能獲得良好的近期療效。
[Abstract]:Objective to compare the surgical methods of gastrointestinal stromal tumors (GIST) by using the data analysis method from the point of view of inquiry medicine. To evaluate the safety and efficacy of laparoscopic assisted resection of gastrointestinal stromal tumors (LAP) and open surgery (OPEN) in the treatment of gastrointestinal stromal tumors (GIST). Methods the database of Pubmedus Elsevier SPRINGERN, the Cochrane Library, etc., published from January 2004 to March 2014, was collected from the Library of Nanchang University for laparoscopic assisted gastrointestinal stromal tumor resection (LAP) and open gastrointestinal stromal tumor resection (GIST). OPEN) A comparative English literature, The literature is screened according to the criteria for inclusion and exclusion, and then the data is extracted and the quality of the literature is evaluated. Finally, Meta analysis was carried out with Review Manager 5.2 software. Results the Meta analysis included 12 articles (719 patients), including 345 patients in LAP group and 374 patients in open group. The results of meta-analysis showed that compared with OPEN, lap had postoperative exhaust time. The time of entering fluid and the time of hospitalization were shorter than that of P0. 04 and P0. 001 + P0. 0001, and the incidence and recurrence rate of postoperative complications were lower than that of P0. 0004 + 0. 005, but there was no significant difference between them in the time of operation and the amount of blood loss during operation. Conclusion compared with OPEN, LAP and OPEN can accelerate the postoperative recovery. Therefore, LAP is technically feasible, has good safety, and can obtain good short-term curative effect.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R735

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相關(guān)期刊論文 前2條

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本文編號(hào)：1543689