本文關(guān)鍵詞： 乳腺腫瘤 放射療法 調(diào)強適形 錐形束CT 配準(zhǔn) 擺位誤差　出處：《中國全科醫(yī)學(xué)》2017年15期 　論文類型：期刊論文

【摘要】：目的探討機載錐形束CT(CBCT)引導(dǎo)下乳腺癌保乳術(shù)后調(diào)強放療(IMRT)不同乳腺厚度時擺位誤差及配準(zhǔn)方式的差異。方法 2016年3—10月,選擇溫州醫(yī)科大學(xué)附屬第一醫(yī)院放化療科接受IMRT的乳腺癌保乳術(shù)后患者85例,在醫(yī)科達Synergy加速器上的機載CBCT引導(dǎo)下,對IMRT治療前擺位進行驗證。把CBCT重建圖像和計劃圖像進行匹配。計算六維方向上的擺位誤差,并在線自動校準(zhǔn)上述誤差。線下分別測量每例患者乳腺厚度(乳腺組織最大徑,即乳腺組織最凸點至最近胸壁肌外緣的距離)并分組,對比分析自動骨性配準(zhǔn)下和自動灰度配準(zhǔn)下X軸(左右)、Y軸(上下)、Z軸(前后)及矢軸位(GX)、冠狀位(GY)、橫狀位(GZ)的擺位誤差。結(jié)果自動骨性配準(zhǔn)下和自動灰度配準(zhǔn)下,85例患者X軸和GY的擺位誤差間差異有統(tǒng)計學(xué)意義(P0.05)。自動骨性配準(zhǔn)下A組(乳腺厚度≤30 mm)、B組(乳腺厚度30~45 mm)、C組(乳腺厚度45 mm)患者各個方向的擺位誤差間差異均無統(tǒng)計學(xué)意義(P0.05);自動灰度配準(zhǔn)下3組患者各個方向的擺位誤差間差異均無統(tǒng)計學(xué)意義(P0.05)。結(jié)論乳腺癌保乳術(shù)后IMRT不同乳腺厚度患者擺位誤差間無明顯差異,兩種配準(zhǔn)方式建議首先使用灰度配準(zhǔn)。放療前進行CBCT引導(dǎo)下擺位誤差校準(zhǔn),可以提高乳腺癌放療的精度,從而實現(xiàn)精確放療。
[Abstract]:Objective to investigate the difference of setting error and registration method in different breast thickness after intensity-modulated radiotherapy (IMRT) guided by CT-CBCT.Methods from March to October, 2016. Eighty-five breast cancer patients who received IMRT in the Department of radiotherapy and chemotherapy, first affiliated Hospital of Wenzhou Medical University, were selected under the guidance of airborne CBCT on the Synergy accelerator. The CBCT reconstruction image was matched with the planned image. The error in six dimensional direction was calculated, and the error was automatically calibrated online. The breast thickness (the maximum diameter of mammary tissue) was measured under the line, respectively. The distance between the most salient spot of breast tissue and the nearest outer edge of the chest wall muscle. Comparative analysis is made of the pendulum errors of the X axis (left and right) under the automatic bone registration and the automatic grayscale registration (upper and lower Z axis (front and back) and sagittal axis (GXT), coronal position (GY), transverse position (GZ)). Results the results of automatic bone registration and automatic gray level registration are as follows: (1) automatic bone registration and (2) automatic grayscale registration. There was significant difference in the error between X axis and GY in 85 cases of inferior mammary gland. The difference between the errors in all directions in group A (breast thickness 鈮，

本文編號：1531138