發(fā)布時(shí)間：2018-07-14 10:02

【摘要】：目的:探討中西醫(yī)結(jié)合治療高尿酸血癥和痛風(fēng)患者的效果。方法:選取2012年2月—2014年2月醫(yī)院收治的高尿酸血癥和痛風(fēng)患者150例,按隨機(jī)數(shù)字表法分為觀察組和對(duì)照組,每組75例。對(duì)照組給予常規(guī)西醫(yī)療法,觀察組在此基礎(chǔ)上加用自擬四妙湯,每日1劑,療程2個(gè)月。比較兩組血尿酸、血沉、CRP、腎功能指標(biāo)變化及不良反應(yīng),并評(píng)價(jià)臨床療效。結(jié)果:觀察組總有效率為96.0%(72/75),顯著高于對(duì)照組的84.0%(63/75),差異有統(tǒng)計(jì)學(xué)意義(χ2=4.26,P0.05)。兩組治療后UA、ESR、CRP均較治療前顯著降低(t=5.45、5.20、4.78、4.56、4.35、4.39,P0.05),兩組比較觀察組較對(duì)照組降低明顯(t=4.11、4.02、4.55,P0.05)。兩組治療后血肌酐、尿素氮均較治療前顯著降低(t=5.45、5.20、4.78、4.56,P0.05),兩組比較觀察組較對(duì)照組降低明顯(t=4.11、4.02,P0.05)。觀察組不良反應(yīng)發(fā)生率為2.7%(2/75),對(duì)照組為12.0%(9/75),差異有統(tǒng)計(jì)學(xué)意義(χ2=4.56,P0.05)。結(jié)論:相比西醫(yī)常規(guī)療法,中西醫(yī)結(jié)合治療高尿酸血癥和痛風(fēng)患者能顯著提高療效,能進(jìn)一步降低血尿酸,消除炎癥,改善腎功能,降低不良反應(yīng),值得臨床推廣應(yīng)用。
[Abstract]:Objective: to investigate the effect of integrated traditional Chinese and western medicine on patients with hyperuricemia and gout. Methods: 150 patients with hyperuricemia and gout were selected from Feb 2012 to Feb 2014, and were divided into observation group (n = 75) and control group (n = 75). The control group was treated with routine western medicine, and the observation group was treated with self-made Simiao decoction once a day for 2 months. The changes of serum uric acid, erythrocyte sedimentation rate (ESR), renal function and adverse reactions were compared between the two groups. Results: the total effective rate of the observation group was 96.0% (72 / 75), which was significantly higher than that of the control group (84.0%) (63 / 75), and the difference was statistically significant (蠂 2 / 4.26 P 0.05). After treatment, the CRP of UAS in both groups was significantly lower than that before treatment (t = 5.45) (t _ (5.45) ~ (5.20) ~ (4.78) ~ (4.65) ~ (4.36) ~ (4.39) (P0.05), and it was significantly lower in the observation group than that in the control group (t _ (4.114.02) ~ (4.55). The levels of serum creatinine and urea nitrogen in the two groups were significantly lower than those before treatment (P 0.05), and those in the observation group were significantly lower than those in the control group (P 0.05). The incidence of adverse reactions was 2.7% (2 / 75) in the observation group and 12.0% (9 / 75) in the control group. The difference was statistically significant (蠂 24.56 P 0.05). Conclusion: compared with conventional western medicine, the treatment of hyperuricemia and gout with integrated traditional Chinese and western medicine can significantly improve the curative effect, further reduce blood uric acid, eliminate inflammation, improve renal function and reduce adverse reactions, which is worthy of clinical application.
【作者單位】： 杭州市第三醫(yī)院內(nèi)科;杭州綠城醫(yī)院中醫(yī)科;杭州市第二醫(yī)院內(nèi)科;
【分類號(hào)】：R589.7

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