發(fā)布時間：2018-05-12 05:18

  本文選題：二甲雙胍 + 針灸�。� 參考：《山東醫(yī)藥》2010年45期

【摘要】：目的探討二甲雙胍聯(lián)合針灸治療對肥胖者胰島素敏感性和代謝的影響。方法將156例單純肥胖者隨機分成A、B、C、D 4組,A組僅給予生活方式干預;其他3組除生活方式干預外,B組給予二甲雙胍、C組給予針灸,D組給予二甲雙胍與針灸聯(lián)合治療;各組受試者均治療3個月。觀察治療前后空腹血糖(FPG)、空腹胰島素(FINS)、體質(zhì)量指數(shù)(BMI)、胰島素敏感性指數(shù)(ISI)、TG、TC、HDL-C、LDL-C的變化。結(jié)果治療前后比較,B、C、D組BMI、FPG、FINS、ISI、HDL-C、TG、LDL-C、TC差異有統(tǒng)計學意義(P0.05或0.01)。治療后D組與B組比較,BMI降低、ISI升高(P均0.05);治療后D組與C組比較,BMI、FPG、FINS、TG、LDL-C、TC降低(P均0.05),HDL-C顯著升高(P0.05)。結(jié)論在生活方式干預基礎(chǔ)上,二甲雙胍聯(lián)合針灸治療單純性肥胖安全、有效。
[Abstract]:Objective to investigate the effect of metformin combined with acupuncture on insulin sensitivity and metabolism in obese patients. Methods 156 patients with simple obesity were randomly divided into two groups: group A received lifestyle intervention only, group B received metformin in addition to lifestyle intervention, group D received combined treatment with acupuncture and moxibustion, and group D received combined treatment with acupuncture and moxibustion. All the subjects were treated for 3 months. The changes of fasting blood glucose (FPG), fasting insulin (FINS), body mass index (BMI) and insulin sensitivity index (ISI) were observed before and after treatment. Results before and after treatment, there were significant differences in LDL-CTC between the two groups (P 0.05 or 0.01). After treatment, group D and group B had lower BMI and higher ISI (P < 0.05) and higher HDL-C (P < 0.05) than those in group D and group C (P < 0.05), respectively, and the decrease of LDL-CU TC in group D and group C were significantly higher than those in group D and group C (P < 0.05). Conclusion on the basis of lifestyle intervention, metformin combined with acupuncture is safe and effective in the treatment of simple obesity.
【作者單位】： 山東省榮軍總醫(yī)院;
【分類號】：R246;R589.2

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相關(guān)期刊論文 前2條

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本文編號：1877260