基于POMDP的不穩(wěn)定心絞痛中西醫(yī)結(jié)合治療方案優(yōu)化研究
發(fā)布時(shí)間:2018-03-12 22:43
本文選題:部分可觀察馬爾科夫決策過(guò)程 切入點(diǎn):不穩(wěn)定心絞痛 出處:《中國(guó)中西醫(yī)結(jié)合雜志》2013年07期 論文類型:期刊論文
【摘要】:目的初步優(yōu)化中西醫(yī)結(jié)合防治不穩(wěn)定心絞痛(unstable angina,UA)的綜合治療方案。方法基于部分可觀察的馬爾科夫決策過(guò)程模型(Partially Observable Markov Decision Process,POMDP)的方法,選擇氣虛、血瘀、痰濁3個(gè)主要證侯要素,對(duì)UA住院患者的診治情況進(jìn)行深層次數(shù)據(jù)挖掘、分析,客觀評(píng)價(jià)UA中西醫(yī)結(jié)合的療效。結(jié)果 UA氣虛證、血瘀證、痰濁證患者的推薦治療方案依次為:硝酸酯類+他汀類+氯吡格雷+血管緊張素Ⅱ受體阻滯劑+肝素類+黃芪+黨參+茯苓+白術(shù)(ADR=0.85077869);硝酸酯類+阿司匹林+氯吡格雷+他汀類+肝素類+當(dāng)歸+紅花+桃仁+赤芍(ADR=0.70773000);硝酸酯類+阿司匹林+他汀類+血管緊張素轉(zhuǎn)換酶抑制劑+栝蔞+薤白+半夏+陳皮(ADR=0.72509600)。結(jié)論本研究基于POMDP優(yōu)化了UA的治療方案,可作為進(jìn)一步規(guī)范和制定中西醫(yī)結(jié)合治療UA方案的參考。
[Abstract]:Objective to optimize the comprehensive treatment of unstable angina pectoris (UAP) with integrated traditional Chinese and western medicine. Methods based on the partially observable Markov Observable Markov Decision Process-POMDP, three main syndromes, namely deficiency of qi, blood stasis and phlegm turbid, were selected. The diagnosis and treatment of UA inpatients were analyzed and analyzed to evaluate objectively the curative effect of the combination of traditional Chinese and western medicine. Results there were Qi deficiency syndrome, blood stasis syndrome, and blood stasis syndrome. The recommended treatment schemes for patients with phlegm turbid syndrome are as follows: nitrate statin clopidogrel angiotensin 鈪,
本文編號(hào):1603604
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