本文選題：強(qiáng)直性脊柱炎　切入點(diǎn)：腹針　出處：《廣州中醫(yī)藥大學(xué)》2011年碩士論文　論文類型：學(xué)位論文

【摘要】：背景 強(qiáng)直性脊柱炎(ankylosing spondylitis, AS)是一種原因不明的慢性炎性疾病,主要侵犯中軸骨,以骶髂關(guān)節(jié)炎和附著病為其特征。強(qiáng)直性脊柱炎雖大多不會(huì)對(duì)人的生命造成嚴(yán)重的威脅,但由于患病者可出現(xiàn)明顯的腰背部僵硬、疼痛,晚期甚至可發(fā)生脊柱強(qiáng)直、畸形,造成嚴(yán)重的軀體功能活動(dòng)障礙,故給患者帶來(lái)很大的痛苦,嚴(yán)重影響患者的生存質(zhì)量。目前尚無(wú)可完全治愈的理想方法,是國(guó)際上公認(rèn)的一種難治疾病。 本文回顧了中西醫(yī)在認(rèn)識(shí)強(qiáng)直性脊柱炎方面的歷程,總結(jié)了中西醫(yī)對(duì)強(qiáng)直性脊柱炎病因、病機(jī)、診斷及藥物、針灸作用機(jī)理等方面的相關(guān)認(rèn)識(shí)及研究,歸納概括了現(xiàn)階段治療強(qiáng)直性脊柱炎的主要方法,論述了腹針治療強(qiáng)直性脊柱炎的理論依據(jù),通過(guò)對(duì)照實(shí)驗(yàn)分析,對(duì)腹針治療強(qiáng)直性脊柱炎的臨床療效做出評(píng)價(jià)。對(duì)今后腹針治療強(qiáng)直性脊柱炎的臨床研究方面提出自己的一些觀點(diǎn)和看法。 目的 本課題通過(guò)對(duì)口服柳氮磺胺吡啶片、雙氯芬酸鈉緩釋片與腹針聯(lián)合口服柳氮磺胺吡啶片、雙氯芬酸鈉緩釋片這兩種方法治療強(qiáng)直性脊柱炎的臨床療效進(jìn)行對(duì)照觀察,應(yīng)用多項(xiàng)量化指標(biāo)對(duì)兩者的療效進(jìn)行評(píng)價(jià),為日后運(yùn)用腹針治療強(qiáng)直性脊柱炎方面的研究及療效評(píng)價(jià)體系的建立提供一定的文獻(xiàn)依據(jù)及數(shù)據(jù)支持。 研究對(duì)象與方法 對(duì)廣東省中醫(yī)院珠海醫(yī)院門診及住院部患者進(jìn)行篩選,符合納入標(biāo)準(zhǔn)的患者共計(jì)40名(針?biāo)幗M19名,藥物組21名)進(jìn)行隨機(jī)對(duì)照研究。兩組即針?biāo)幗M和藥物組均接受西藥治療,即口服雙氯芬酸鈉緩釋片75mg,每日1次；柳氮磺胺吡啶片第1周每次口服0.5g,每日3次,第2周每次口服0.75g,每日3次,第3周起每次口服1.0g,每日3次,維持至3個(gè)月治療結(jié)束。針?biāo)幗M在此基礎(chǔ)上,加用薄氏腹針進(jìn)行治療�；咎幏剑褐须�(D)、下脘(D)、氣海(D)、關(guān)元(D)、中極(D)、氣穴(D)、大橫雙(M)、外陵雙(M)、滑肉門雙(M)。下腰椎及骶椎疼痛,根據(jù)部位高低加關(guān)元上或關(guān)元下。合并髖關(guān)節(jié)疼痛：下風(fēng)濕內(nèi)點(diǎn)M(患)。必要時(shí)并配合局部定位取穴。手法采用輕刺激,無(wú)酸麻脹痛感,但指下有如魚(yú)吞餌之沉緊。施術(shù)后留針20-30分鐘,針后10分鐘左右調(diào)針一次。每周一至六連續(xù)治療6天后休息1天,連續(xù)治療3個(gè)月。兩組的主要療效觀測(cè)指標(biāo)包括疼痛評(píng)分、ESR、HSCRP、IgA、IgG、IgM水平、指地距、擴(kuò)胸距和20m步行時(shí)間。將相關(guān)數(shù)據(jù)錄入數(shù)據(jù)庫(kù),建立數(shù)據(jù)庫(kù)系統(tǒng),運(yùn)用相關(guān)軟件進(jìn)行統(tǒng)計(jì)學(xué)分析,最后得出結(jié)論。 結(jié)果 本研究的數(shù)據(jù)結(jié)果顯示：腹針配合藥物治療強(qiáng)直性脊柱炎3個(gè)月,對(duì)與強(qiáng)直性脊柱炎相關(guān)的主要癥狀、體征及指標(biāo),如：疼痛評(píng)分、ESR、HSCRP、IgA、IgG、IgM水平、指地距、擴(kuò)胸距和20m步行時(shí)間,都有明顯的改善作用,其中在疼痛評(píng)分、ESR、IgA水平、指地距、擴(kuò)胸距及20m步行時(shí)間方面腹針配合藥物治療效果更優(yōu)于單純藥物治療。腹針配合藥物與單純藥物治療強(qiáng)直性脊柱炎其顯著療效差異有統(tǒng)計(jì)學(xué)意義。 結(jié)論 薄氏腹針配合柳氮磺胺吡啶片、雙氯芬酸鈉緩釋片治療強(qiáng)直性脊柱炎可以取得良好的療效。
[Abstract]:background
Ankylosing spondylitis (ankylosing spondylitis AS) is a chronic inflammatory disease of unknown cause, mainly affects the axial skeleton, with sacroiliitis and infirmity is characterized. Although most of ankylosing spondylitis does not pose a serious threat to human life, but because the disease can be significant lower back stiffness. Pain, late or even spinal stiffness, deformity, causing severe body movement disorder, so it brings great suffering to patients, seriously affect the life quality of the patients. No ideal method can be completely cured, is considered the a refractory disease.
This paper reviews the progress in the understanding of ankylosing spondylitis of traditional Chinese medicine and Western medicine, summarizes the Chinese and Western medicine in the etiology, pathogenesis, diagnosis and drug related knowledge and research of acupuncture mechanism, summed up the main methods at this stage in the treatment of ankylosing spondylitis, discusses the theoretical basis for the treatment of ankylosing spondylitis abdominal acupuncture, by contrast experiment analysis, the clinical curative effect of abdominal acupuncture in the treatment of ankylosing spondylitis. To evaluate future clinical research of abdominal acupuncture in the treatment of ankylosing spondylitis and put forward some own views and opinions.
objective
Based on the study of oral sulfasalazine tablets, Diclofenac Sodium Sustained Release Tablets and abdominal acupuncture combined with oral sulfasalazine tablets, the clinical curative effect of Diclofenac Sodium Sustained Release Tablets of the two methods in the treatment of ankylosing spondylitis were observed to evaluate the curative effect of applying a number of quantitative indicators of the two, the establishment of the day after the application and curative effect of abdominal acupuncture treatment of ankylosing as the evaluation system to provide literature basis and data support.
Research objects and methods
瀵瑰箍涓滅渷涓尰闄㈢彔嫻峰尰闄㈤棬璇婂強(qiáng)浣忛櫌閮ㄦ?zhèn)ｈ�呰繘琛岀瓫閫，

本文編號(hào)：1560005