【摘要】：目的：初步探討職業(yè)電磁輻射暴露及其他危險(xiǎn)因素與老年人認(rèn)知功能障礙的關(guān)系 方法：選取總參通訊部北京第一干休所軍隊(duì)離退休老干部為研究對象，設(shè)計(jì)調(diào)查問卷，由經(jīng)過培訓(xùn)的調(diào)查員進(jìn)行面對面問卷調(diào)查，化驗(yàn)檢查按統(tǒng)一要求和操作程序進(jìn)行，在解放軍總醫(yī)院生化科完成。所有數(shù)據(jù)錄入Access數(shù)據(jù)庫，并導(dǎo)入SPSS12.0版統(tǒng)計(jì)軟件進(jìn)行分析。根據(jù)簡易精神狀態(tài)檢查量表得分將研究對象分為認(rèn)知功能異常組和正常組進(jìn)行比較，單因素分析計(jì)算OR值(95％可信限)和t值；多因素分析采用非條件Logistic逐步回歸模型。 結(jié)果： 1．社會人口學(xué)情況：本研究實(shí)際調(diào)查273人(男229，女44)，平均68.8±5.8歲，其中已婚者254人(占總體的93.0％)，，腦力勞動(dòng)者占大多數(shù)(97.1％)。 2．單因素分析結(jié)果顯示吸煙、腦卒中病史和慢性阻塞性肺病病史在兩組間差異明顯，其OR值(95％可信限)分別為2.61(1.16-5.88)、5.09(2.05-12.68)和2.74(1.15-6.54)。 3．多因素分析結(jié)果顯示調(diào)整了年齡、性別及其他影響因素后，吸煙、飲酒、收縮壓水平增高、膽固醇水平增高和腦卒中病史是認(rèn)知功能損傷的危險(xiǎn)因素，OR值(95％可信限)分別為3.87(1.40-10.68)、4.07(1.12-14.79)、1.04(1.01-1.07)、2.04(1.11-3.74)、4.79(1.56-14.68)；電磁暴露的OR值(95％可信限)為0.60(0.24-1.51)。 結(jié)論：吸煙、飲酒、腦卒中病史、血壓升高和高膽固醇血癥是促使認(rèn)知功能減退的危險(xiǎn)因素，未能發(fā)現(xiàn)電磁暴露與認(rèn)知功能改變的關(guān)系。
[Abstract]:Objective: to explore the relationship between occupational electromagnetic radiation exposure and other risk factors and cognitive impairment in the elderly. The questionnaire was designed and investigated face to face by trained investigators. The laboratory examination was carried out according to the unified requirements and operation procedures and was completed in the biochemical Department of PLA General Hospital. Input all data into Access database, and import SPSS12.0 version of statistical software for analysis. The subjects were divided into cognitive dysfunction group and normal group according to the scores of simple mental state examination. The OR value (95% confidence limit) and t value were calculated by univariate analysis, and the non-conditional Logistic stepwise regression model was used in multivariate analysis. Results: 1. Social demography: 273 people (229 males, 44 females) were investigated in this study, with an average age of 68.8 鹵5.8 years, of which 254 (93.0%) were married. Mental labor accounted for the majority (97.1%). 2. Univariate analysis showed that smoking, stroke history and chronic obstructive pulmonary disease history were significantly different between the two groups, and their OR values (95% confidence limit) were 2.61 (1.16-5.88), respectively. 5.09 (2.05-12.68) and 2.74 (1.15-6.54). 3. The results of multivariate analysis showed that after adjusting for age, sex and other influencing factors, smoking, drinking, systolic blood pressure, cholesterol and stroke history were risk factors of cognitive impairment. The OR values (95% confidence limit) were 3.87 (1.40-10.68), 4.07 (1.12-14.79), 1.04 (1.01-1.07), 2.04 (1.11-3.74), 4.79 (1.56-14.68), respectively. The OR value of electromagnetic exposure (95% confidence limit) was 0.60 (0.24-1.51). Conclusion: smoking, drinking, stroke history, elevated blood pressure and hypercholesterolemia are the risk factors of cognitive dysfunction.
【學(xué)位授予單位】：中國人民解放軍軍醫(yī)進(jìn)修學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2004
【分類號】：R82

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 李大強(qiáng),張曉君,朱麗萍,耿稚萍;MMSE的三種分界標(biāo)準(zhǔn)在阿爾茨海默病篩查中的應(yīng)用比較[J];北京醫(yī)學(xué);2001年01期

2 王樹興;吸煙與老年癡呆[J];國外醫(yī)學(xué)(衛(wèi)生學(xué)分冊);2000年06期

3 楊政權(quán),汪培山;吸煙、飲酒與腦出血的配對病例對照研究[J];疾病控制雜志;1999年02期

4 解恒革,王魯寧,王曉紅,王振福,齊增飛;軍隊(duì)離退休干部癡呆患病率及危險(xiǎn)因素的初步研究[J];解放軍醫(yī)學(xué)雜志;2000年05期

5 張展星;上海寶山區(qū)老年癡呆患者分布狀況調(diào)查[J];健康心理學(xué)雜志;2000年05期

6 費(fèi)偉民,程鎏,王玉梅,胡喜榮,孫才堅(jiān),高之旭;上海市盧灣區(qū)一個(gè)社區(qū)老年期癡呆患病率分析[J];四川精神衛(wèi)生;2001年01期

7 王小娟,霍東紅,鄧商智;西安近郊縣老年人群認(rèn)知功能相關(guān)因素分析[J];現(xiàn)代預(yù)防醫(yī)學(xué);1999年02期

8 何育生,王星,陳輝新,陸振康;腦梗死后癡呆的臨床分析[J];中風(fēng)與神經(jīng)疾病雜志;2001年04期

9 洪霞,張振馨,李輝,趙潔皓,魏鏡,黃覺斌,楊恩立,吳繼星,冀成君,張曉君;內(nèi)源性雌激素與阿爾茨海默病的病例對照研究[J];中華流行病學(xué)雜志;2001年05期

10 姚佳紅,李輝,張振馨;阿爾茨海默病與家族史病例對照研究[J];中華流行病學(xué)雜志;2002年01期

本文編號：2323036