【摘要】：目的探討犬腹部外傷合并海水浸泡后高滲及低溫因素對其出凝血系統(tǒng)的影響,并觀察在一般急救處理同時加用血漿救治的效果,為海戰(zhàn)傷早期救治提供實(shí)驗(yàn)依據(jù)。方法將24只犬作腹部開放傷動物模型后,隨機(jī)均分為3組,每組8只。對照組:不用海水浸泡;普通治療組:經(jīng)海水浸泡后打撈出水,給予一般的急救處理;血漿組:經(jīng)海水浸泡后打撈出水,給予一般的急救處理,同時輸注血漿。記錄各組生存時間、體溫、平均動脈壓、血漿滲透壓、凝血酶原時間(PT)、部分凝血活酶時間(KFTT)、D-二聚體、凝血因子Ⅱ等變化以及臟器病理特點(diǎn)。結(jié)果海水浸泡后動物PT、KPTT明顯延長,D-二聚體增加,凝血因子Ⅱ減少。動物生存時間,血漿組(45.6±1
[Abstract]:Objective to investigate the effect of hyperosmotic and hypothermic factors on the coagulation system after abdominal trauma combined with seawater immersion, and to observe the effect of adding plasma in general emergency treatment to provide experimental evidence for early treatment of naval trauma. Methods 24 dogs were randomly divided into 3 groups, 8 in each group. Control group: no seawater immersion; common treatment group: after seawater immersion salvage effluent, give general first aid treatment; Plasma group: after seawater immersion salvage effluent, give general first aid treatment, at the same time infusion plasma. Survival time, body temperature, mean arterial pressure, plasma osmotic pressure, prothrombin time, (PT), partial thromboplastin time, (KFTT) D-dimer, coagulation factor 鈪，

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