本文選題：爆炸傷 + 海岸��； 參考：《中國矯形外科雜志》2006年08期

【摘要】：[目的]建立海岸及海水中兔肢體關(guān)節(jié)爆炸模型,觀察爆炸傷的組織學(xué)改變。[方法]健康家兔112只,隨機分為預(yù)實驗組(A組,n=36),分別以0.3、0.6、0.9、1.2 g單質(zhì)猛炸藥黑索金(RDX)銅殼小型爆炸裝藥捆綁于兔膝關(guān)節(jié)前外側(cè),電引爆,測量比較肢體關(guān)節(jié)炸傷情況;海岸實驗組(B組,n=56),0.9 g RDX銅殼小型爆炸裝藥引爆,傷口包扎后浸入海水中1 h;海水中實驗組(C組,n=20),0.9 g RDX銅殼小型爆炸裝藥捆綁于兔膝關(guān)節(jié)前外側(cè),浸入海水中、電引爆。B組炸傷后、海水浸泡后及C組炸傷后分別取肌肉、韌帶、滑膜、軟骨作組織學(xué)觀察。[結(jié)果]A組比較不同裝藥量爆炸結(jié)果,選定0.9 g RDX銅殼小型爆炸裝藥,海綿間隔6 cm軟固定于兔膝關(guān)節(jié)前外側(cè)爆炸,13只兔造成(5.17±0.42)cm×(4.73±0.41)cm爆炸傷口,銅質(zhì)爆炸破片侵入傷口內(nèi),髕韌帶、股骨外髁軟骨面不同程度損傷。B組均造成肢體關(guān)節(jié)開放傷,海水浸泡1 h后組織學(xué)觀察突出變化是肌肉及滑膜組織水腫、肌肉組織廣泛壞死及韌帶組織中出現(xiàn)大量Ⅲ型膠原。C組14只兔海水中爆炸,均為肢體關(guān)節(jié)閉合性爆炸傷,肢體關(guān)節(jié)高度腫脹,脛股骨多發(fā)骨折,爆炸破片深及皮內(nèi)。組織學(xué)觀察見肌纖維斷裂,肌間血管充血,軟骨組織輕度變性,軟骨細(xì)胞核固縮,核碎裂。[結(jié)論]0.9 g RDX銅殼爆炸裝藥間隔6 cm固定于兔膝關(guān)節(jié)前外側(cè),海岸上爆炸在沖擊波和爆炸破片共同作用下造成肢體關(guān)節(jié)開放爆炸傷,海水浸泡1 h加重了組織腫脹,壞死;海水中爆炸,主要為爆炸沖擊波的作用,造成肢體關(guān)節(jié)閉合性爆炸傷,脛股骨多發(fā)骨折,軟組織損傷、出血更為嚴(yán)重。
[Abstract]:Objective to establish an explosion model of rabbit limb joint in coastal and sea water, and to observe the histological changes of explosive injury. [methods] 112 healthy rabbits were randomly divided into experimental group (group A, n = 36). Small explosive charge of RDX copper shell (RDX) was applied to the anterolateral side of the knee joint of rabbits. In the coastal experimental group (group B) (group B), 0.9 g RDX copper shell small explosive charge detonated, wound bandaged and immersed in seawater for 1 hour; in seawater test group (group C, group C), 0.9 g RDX copper shell small explosive charge was bound to the anterior and outer sides of the knee joint of the rabbit and immersed in seawater. The muscles, ligaments, synovium and cartilage were taken after electrical detonation, seawater immersion and C group. [results] in group A, the small explosive charge of 0.9 g RDX copper shell was selected. The spongy interval of 6 cm was soft fixed on the anterolateral side of the knee joint of 13 rabbits, resulting in (5.17 鹵0.42) cm 脳 (4.73 鹵0.41) cm explosive wound. The copper explosive fragment intruded into the wound and patellar ligament. In group B, open injury of limb joint was caused by different degree of injury of femoral external condylar cartilage. Histologically, edema of muscle and synovium was observed after 1 hour of seawater immersion. Extensive necrosis of muscle tissue and a large number of collagen 鈪，

本文編號：2064725