本文關(guān)鍵詞：駐島士兵皮膚屏障功能與皮膚癬菌感染的相關(guān)性研究　出處：《桂林醫(yī)學(xué)院》2013年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 皮膚屏障功能 經(jīng)表皮水分丟失量 皮脂含量 角質(zhì)層含水量 皮膚癬菌 士兵

【摘要】：目的：研究駐島士兵皮膚屏障功能與皮膚癬菌感染的相關(guān)性。 方法：1.皮膚屏障功能檢測(cè)，，反映皮膚屏障功能的三個(gè)指標(biāo)（經(jīng)表皮丟失水量、皮脂含量、角質(zhì)層含水量）均使用德國(guó)CK公司生產(chǎn)的多功能皮膚測(cè)試儀MPA9進(jìn)行測(cè)量；測(cè)試環(huán)境溫度為22~24℃，相對(duì)濕度為46%~55%；檢測(cè)皮膚屏障功能前，研究對(duì)象先進(jìn)入指定地方適應(yīng)環(huán)境15分鐘等待檢測(cè)。受測(cè)部位為面部、腹股溝區(qū)，在受試部位每個(gè)指標(biāo)進(jìn)行3次測(cè)量，取平均值。角質(zhì)層含水量和皮脂含量的單位均為au (arbitraryunit)，經(jīng)表皮水分丟失量的單位為g/m2h。2.真菌檢查，符合條件的93名研究對(duì)象均在相應(yīng)部位無(wú)菌條件下刮取皮屑進(jìn)行真菌鏡檢和培養(yǎng)。采用15%KOH溶液進(jìn)行鏡檢，采用沙式瓊脂培養(yǎng)基(含0.25%放線菌酮的葡萄糖、氯霉素、蛋白胨、瓊脂培養(yǎng)基),平皿多點(diǎn)接種或雙試管進(jìn)行培養(yǎng),25~27℃培養(yǎng)。 結(jié)果：面部各組的經(jīng)表皮水分丟失量均值之間比較無(wú)明顯統(tǒng)計(jì)學(xué)意義（F=0.611，P＞0.05）；即面部所測(cè)樣本中經(jīng)表皮水分丟失量各組無(wú)明顯差異，與皮膚癬菌感染無(wú)相關(guān);腹股溝各組的經(jīng)表皮水分丟失量均值之間比較可見(jiàn)明顯統(tǒng)計(jì)學(xué)意義（F=104.525，P＜0.05），兩兩比較的結(jié)果都是P＜0.05，即真菌陽(yáng)性組與真菌陰性組、真菌陽(yáng)性組與正常對(duì)照組、真菌陰性組與正常對(duì)照組之間比較具有明顯統(tǒng)計(jì)學(xué)差異，即腹股溝所測(cè)樣本中經(jīng)表皮水分丟失量各組有明顯差異，與皮膚癬菌感染有相關(guān)性。 面部各組的皮脂含量均值之間比較有明顯統(tǒng)計(jì)學(xué)意義（F=95.461， P＜0.05），兩兩比較亦均P＜0.05，即真菌陽(yáng)性組與真菌陰性組、真菌陽(yáng)性組與正常對(duì)照組、真菌陰性組與正常對(duì)照組之間比較具有明顯統(tǒng)計(jì)學(xué)差異，即所測(cè)樣本面部皮脂含量與皮膚癬菌感染有相關(guān)性；腹股溝各組的皮脂含量均值之間比較無(wú)明顯統(tǒng)計(jì)學(xué)意義（F=1.29， P＞0.05），即所測(cè)數(shù)據(jù)腹股溝皮脂含量與皮膚癬菌感染無(wú)相關(guān)性。 面部各組的角質(zhì)層含水量均值之間比較無(wú)明顯統(tǒng)計(jì)學(xué)意義（F=0.840，P＞0.05），即所測(cè)數(shù)據(jù)腹股溝角質(zhì)層含水量與皮膚癬菌感染無(wú)相關(guān)性。腹股溝各組的角質(zhì)層含水量均值之間比較無(wú)明顯統(tǒng)計(jì)學(xué)意義（F=3.015，P＞0.05），即所測(cè)數(shù)據(jù)腹股溝角質(zhì)層含水量與皮膚癬菌感染無(wú)相關(guān)性。 面部真菌陽(yáng)性組、真菌陰性組、正常對(duì)照組所測(cè)樣本中經(jīng)表皮水分丟失量、皮脂含量、角質(zhì)層含水量與年齡、軍齡、駐島時(shí)間之間關(guān)系均無(wú)明顯統(tǒng)計(jì)學(xué)意義（P＞0.05）。 腹股溝真菌陽(yáng)性組所測(cè)樣本中經(jīng)表皮水分丟失量、皮脂含量、角質(zhì)層含水量與年齡、軍齡、駐島時(shí)間之間關(guān)系均無(wú)明顯統(tǒng)計(jì)學(xué)意義（P＞0.05）；腹股溝真菌陰性組與正常對(duì)照組所測(cè)樣本中經(jīng)表皮水分丟失量、角質(zhì)層含水量與年齡、軍齡、駐島時(shí)間之間關(guān)系無(wú)明顯統(tǒng)計(jì)學(xué)意義（P＞0.05）；由于腹股溝真菌陰性組與正常對(duì)照組所測(cè)樣本中皮脂含量均為0，無(wú)法計(jì)算出其與其他因素的關(guān)系。 結(jié)論：（1）駐島部隊(duì)士兵患皮膚癬菌感染的腹股溝經(jīng)表皮水分丟失量與皮膚癬菌感染存在相關(guān)性； （2）駐島部隊(duì)士兵患皮膚癬菌感染的面部皮脂含量亦與皮膚癬菌感染存在相關(guān)性。 （3）駐島部隊(duì)士兵患皮膚癬菌感染的面部、腹股溝角質(zhì)層含水量與皮膚癬菌感染無(wú)相關(guān)性。 （4）駐島部隊(duì)士兵患皮膚癬菌感染的面部、腹股溝皮膚屏障功能與年齡、軍齡以及駐島時(shí)間無(wú)相關(guān)性。
[Abstract]:Objective: To study the relationship between the skin barrier function of the soldiers in the island and the infection of dermatitis.
Methods: 1. skin barrier function test, three indexes of skin barrier function (transepidermal water loss, sebum content, water content in stratum corneum) were using the MPA9 multifunctional skin test instrument produced by German CK were measured; the test environment temperature of 22~24, the relative humidity is 46%~55%; detection of skin barrier function. The research object first enter the designated place to adapt to the environment for 15 minutes waiting for detection. The measured parts for facial, inguinal area in the subjects part of each indicator for measuring 3 times, the average. The cuticle moisture and sebum content units are Au (arbitraryunit), transepidermal water loss per unit of g/m2h.2. fungi for inspection, 93 subjects were eligible in the corresponding position under aseptic conditions to scrape scurfy microscopy and fungal culture. Microscopic examination using 15%KOH solution, using sand type agar medium (containing 0.25% line The glucose of ketone, chloramphenicol, peptone, agar medium, multi point inoculation or double test tube were cultured and cultured at 25~27.
Results: the face of each transepidermal water loss between the average value was not statistically significant (F=0.611, P > 0.05); facial samples in transepidermal water loss was not obvious difference, and dermatophyte infection related; transepidermal water loss is obvious statistical significance between mean inguinal groups (F=104.525, P < 0.05), the 22 results are P < 0.05, the fungal positive group and negative group of fungi, fungal positive group and normal control group, compared with significant statistical difference between fungal negative group and normal control group, the groin samples in transepidermal water loss groups have obvious difference that is associated with dermatophyte infection.
Comparison was statistically significant between the mean of each facial sebum content (F=95.461, P < 0.05), 22 were P < 0.05, the fungal positive group and negative group of fungi, fungal positive group and normal control group, compared with significant statistical difference between fungal negative group and normal control group, which is measured by the facial sebum the content of sample and dermatophyte infection have correlation between mean sebum content; inguinal groups was not statistically significant (F=1.29, P > 0.05), the test had no correlation with inguinal sebum content data of dermatophyte infection.
The cuticle facial moisture mean between groups was not statistically significant (F=0.840, P > 0.05), i.e. the data measured by the water content of stratum corneum and inguinal dermatophyte infection. No correlation between cuticle water content between the mean inguinal groups had no significant statistical significance (F=3.015, P > 0.05), i.e. the measured data of inguinal water content in stratum corneum and dermatophyte infection had no correlation.
The face of fungal fungal positive group and negative group, normal control group samples in transepidermal water loss, sebum content, water content in stratum corneum with age, length of military service, the relationship between the island time were no statistical significance (P > 0.05).
Inguinal fungal samples positive group in transepidermal water loss, sebum content, water content in stratum corneum with age, length of military service, the relationship between the island time were no statistical significance (P > 0.05); inguinal fungal negative group and normal control group samples in transepidermal water loss, water content in stratum corneum with age, the relationship between the time of military service, stationed in the island was not statistically significant (P > 0.05); because of a groin fungal negative group and normal control group by measuring the sebum content in samples was 0, to calculate its relationship with other factors.
Conclusions: (1) there is a correlation between the loss of the epidermis of the groin and the infection of the derma of the troop infected soldiers in the island.
(2) the content of the skin sebum in the soldiers suffering from dermworm infection in the island troops is also associated with dermatitis infection.
(3) there was no correlation between the water content of the horny layer of the groin and the infection of dermworm infection in the soldiers suffering from dermatitis in the island troops.
(4) the garrison soldiers suffering from dermatophyte infection face, groin skin barrier function and age, no correlation between military service and stationed in the island.

【學(xué)位授予單位】：桂林醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R82

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 徐沖;關(guān)鵬舉;;廣西云南邊防前線皮膚病防治調(diào)查分析[J];人民軍醫(yī);1988年06期

2 吳艷;牛悅青;陳璨;仲少敏;劉慧賢;許月;孫楠;;皮膚屏障與玫瑰痤瘡相關(guān)性的研究進(jìn)展[J];皮膚病與性病;2011年02期

3 何黎;;皮膚屏障與保濕[J];實(shí)用醫(yī)院臨床雜志;2009年02期

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