【摘要】：目的：對(duì)同一組受試人群實(shí)施兩種不同模式的反復(fù)體位改變刺激,研究?jī)煞N反復(fù)體位改變對(duì)心血管調(diào)節(jié)功能影響的差異、刺激特點(diǎn)和應(yīng)用方向。 方法：使12名受試者在旋轉(zhuǎn)床上進(jìn)行兩種模式的反復(fù)體位改變?cè)囼?yàn),并在試驗(yàn)前、后5min對(duì)受試者進(jìn)行5min+75°的心血管反應(yīng)測(cè)試(HUT)。反復(fù)體位改變程序如下：HDT/HUT模式：0°,5min—-15°,1.5min—+50°,1min—+15°,1.5min—+50°,1min—-15°,1.5min—+50°,1min—-30°,2min—+50°,1min—-30°,2min—+50°,1min—-30°,2min—+50°,1min—-45°,3min—+50°,1min—-45°,3min—+50°,1min—-30°,2min—+50°,1min—-15°,1.5min—+50°,1min—0°,5min: SUP/HUT模式：0°,2min—+75°,1min,重復(fù)十次。以平臥位參數(shù)為對(duì)照,選取受試者在每個(gè)體位20s、60s時(shí)的心率(HR)、血壓(SBP,DBP,MBP)、每搏量(SV)、心輸出量(CO)、總外周阻力(TPR)等指標(biāo)時(shí)行分析。 結(jié)果：1)HDT/HUT模式使受試者在之后的HUT檢查時(shí)心血管反應(yīng)指數(shù)(CRI)顯著升高；DBP、MBP、CO在HUT1min時(shí)較試驗(yàn)前顯著下降；SUP/HUT模式的試驗(yàn)對(duì)CRI值、立位時(shí)的BP沒有影響。2)兩種模式的反復(fù)體位改變?cè)嚻陂g,多項(xiàng)心血管參數(shù)變化明顯,并呈現(xiàn)出規(guī)律性的變化。3)除前兩次體位改變外,HDT/HUT模式的△BP小于SUP/HUT模式的△BP。在每個(gè)體位(第八次除外)的20s,HDT/HUT的△SV、△CO都小于SUP/HUT的△SV、△CO.4)HDT/HUT模式中,第十次-15？0s、+5020s時(shí)的SBP(p0.05).MBP低于第一次；第十次+5060s時(shí)SBP低于第一次,DBP、MBP升高(p0.05)；TPR高于第一次(p0.05)。SUP/HUT模式中,除第十次060s時(shí)的SBP低于與第一次之外(p0.05),SBP、DBP、MBP、TPR都顯著高于第一次。兩種模式試驗(yàn)SV、CO的變化趨勢(shì)相似。 結(jié)論：1)兩種模式的反復(fù)體位改變?cè)囼?yàn)對(duì)心血管調(diào)節(jié)功能造成的影響具有一定差異；2)與HDT/HUT模式的反復(fù)體位試驗(yàn)相比,機(jī)體能夠更好地適應(yīng)SUP/HUT模式的反復(fù)體位改變?cè)囼?yàn)對(duì)心血管造成的影響；3)HDT/HUT模式的反復(fù)體位改變?cè)囼?yàn)有可能用于預(yù)備航天員的選拔,SUP/HUT模式的反復(fù)體位改變?cè)囼?yàn)有可能用于航空、航天飛行前的“熱身訓(xùn)練”。
[Abstract]:Objective: to study the effects of repeated postural changes on cardiovascular regulation in the same group of subjects. Methods: 12 subjects were subjected to repeated posture change tests in two different modes on a rotating bed, and (HUT). Was tested by 5min 75 擄cardiovascular response test after 5min before the trial. The procedure of repeated posture change was as follows: HDT/HUT mode: 0 擄, 5min--15 擄, 1.5min-50 擄, 1min-15 擄, 1.5min-50 擄, 1min--15 擄, 1.5min-50 擄, 1min--30 擄, 2min-50 擄, 1min--30 擄, 2min-50 擄, 1min--30 擄. 2min-50 擄, 1min--45 擄, 3min-50 擄, 1min--45 擄, 3min-50 擄, 1min--30 擄, 2min-50 擄, 1min--15 擄, 1.5min-50 擄, 1min-0 擄, 5 min: SUP/HUT mode: 0 擄, 2 min-75 擄, 1 min, repeat ten times. Heart rate (HR), blood pressure (SBP,DBP,MBP) and total peripheral resistance (TPR) of (SV), cardiac output (CO),) were measured at 20 s to 60 s in each postural position. The parameters of supine position were compared. Results: 1) HDT/HUT model significantly increased the cardiovascular response index (CRI) during the later HUT examination, DBP,MBP,CO decreased significantly at HUT1min. The SUP/HUT model test had no effect on the CRI value and the BP in standing position. 2) during the repeated posture change test of the two models, many cardiovascular parameters changed obviously and showed regular changes. 3) except for the first two changes in posture, there were significant changes in cardiovascular parameters. The BP of the HDT/HUT mode is smaller than the BP. of the SUP/HUT mode The SV, CO of 20s HDT / HUT in each position (except for the eighth time) was lower than that of SUP/HUT 's (SV, CO.4) HDT/HUT model. The SBP (p0.05). MBP) at the 10th and 5020s was lower than that of the first one. At the tenth time of 5060s, SBP was lower than that of the first time, and DBP,MBP increased (p0.05). TPR was higher than that of the first (p0.05). In the SUP/HUT model, the SBP at the tenth 060s was lower than that at the first (p0.05), and the SBP,DBP,MBP,TPR was significantly higher than that at the first time (p0.05). The variation trend of SV,CO was similar between the two models. Conclusion: 1) there are some differences in the effects of repeated posture change test between the two models on cardiovascular regulatory function; 2) compared with the repeated posture test of HDT/HUT mode, the body can better adapt to the effect of repeated posture change test of SUP/HUT mode on cardiovascular system. 3) the repeated posture change test of HDT/HUT mode may be used to prepare astronauts for selection, and the repeated posture change test of SUP/HUT mode may be used for "warm-up training" before aviation and aerospace flight.
【學(xué)位授予單位】：北京體育大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：G804.2

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