功能CT評(píng)估肝癌患者肝儲(chǔ)備功能與介入治療風(fēng)險(xiǎn)關(guān)系的價(jià)值
[Abstract]:Objective to evaluate the relationship between hepatic reserve function and risk of interventional therapy in patients with hepatocellular carcinoma (HCC) by functional CT. Methods from March 2012 to October 2015, 64 patients with primary liver cancer were selected from the fourth affiliated Hospital of Guangzhou Medical University and the second affiliated Hospital of Guangzhou Medical University. The data of clinical treatment and CT imaging were all preserved. All the patients received (TACE) interventional therapy after transcatheter arterial chemoembolization (TACE), and were given double phase enhanced scanning before TACE and CT cirrhosis grading. The serum total bilirubin (TBIL), was detected 1 month after TACE. Serum albumin (ALB) was used to evaluate the liver function damage. The CT imaging data of severe liver function impairment group (group A, 23 cases) and mild liver function impairment group (group B, 41 cases) after TACE operation were observed retrospectively. The 2-year survival rate and indocyanine green retention rate (ICGR15) in patients with different CT liver cirrhosis grades were further compared. Results there was significant difference in the number of hepatic perfusion parameters (HAP,PVP,TLP,HBF) between the two groups before TACE (P0.05). CT cirrhosis grade: I 12 cases, II 28 cases, III 16 cases, IV 8 cases. The prognosis analysis showed that ICGR15 in I-II grade of CT cirrhosis was (7.45 鹵2.14)%. The 2-year survival rate of 72.5% (29 / 40) was significantly higher than that of III-IV (16.22 鹵3.16)% and 45.8% (11 / 24) (P0.05). Conclusion the hepatic perfusion parameters of functional CT scan and the grading of liver cirrhosis with CT can be used to evaluate liver reserve function and risk of TACE and provide important basis for evaluation of liver reserve function and clinical treatment.
【作者單位】: 廣州醫(yī)科大學(xué)附屬第四醫(yī)院放射;廣州醫(yī)科大學(xué)附屬第二醫(yī)院放射科;
【分類(lèi)號(hào)】:R445.3;;R735.7
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