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自適應(yīng)統(tǒng)計(jì)迭代重建技術(shù)在降低學(xué)齡前兒童胸部CT檢查輻射劑量的應(yīng)用研究

發(fā)布時(shí)間:2018-09-01 05:23
【摘要】:目的:探討自適應(yīng)統(tǒng)計(jì)迭代重建技術(shù)(ASiR)在學(xué)齡前兒童胸部CT掃描中的應(yīng)用價(jià)值。方法:臨床預(yù)試驗(yàn):選取0-1歲胸部CT檢查患兒80名,隨機(jī)分為4組,每組20名;1-3歲胸部CT檢查患兒140名,隨機(jī)分為7組,每組20名;3-6歲胸部CT檢查患兒180名,隨機(jī)分為9組,每組20名;預(yù)設(shè)噪聲指數(shù)范圍為9-17,均采用Z軸自動(dòng)管電流調(diào)節(jié)技術(shù)、管電壓100KV,管電流20-150 m A,FBP重建,比較分析不同噪聲指數(shù)條件下影像SNR、影像噪聲、CTDIvol、DLP、ED等,并對(duì)影像質(zhì)量進(jìn)行評(píng)價(jià),尋找滿足診斷要求各年齡段患兒噪聲指數(shù)的最大臨界值。臨床試驗(yàn):選取0-1歲、1-3歲、3-6歲行胸部CT平掃+增強(qiáng)檢查患兒各30名;平掃序列,0-1歲患兒預(yù)設(shè)噪聲指數(shù)為12,1-3歲患兒預(yù)設(shè)噪聲指數(shù)為15,3-6歲患兒預(yù)設(shè)噪聲指數(shù)為17,采用Z軸自動(dòng)管電流調(diào)節(jié)技術(shù)、管電壓100KV,管電流20-150m A;增強(qiáng)掃描序列,0-6歲患兒預(yù)設(shè)噪聲指數(shù)均為9,其余掃描參數(shù)與平掃序列相同;患兒增強(qiáng)掃描序列數(shù)據(jù)采用FBP重建算法;患兒胸部平掃序列數(shù)據(jù)采用自適應(yīng)統(tǒng)計(jì)迭代重建技術(shù)(ASiR)進(jìn)行圖像重建,以10%為步漲值,重建為0%-100%等11組圖像,0%即為傳統(tǒng)的FBP重建算法,比較分析不同權(quán)重ASi R重建技術(shù)條件下影像SNR、影像噪聲等,并分析比較各組影像的主觀質(zhì)量,探求出0-6歲患兒在各個(gè)年齡階段行胸部CT掃描時(shí)不同權(quán)重ASiR重建技術(shù)與胸部CT影像質(zhì)量的關(guān)系,并探求其ASiR重建技術(shù)的最佳權(quán)重范圍。結(jié)果:臨床預(yù)試驗(yàn):0-1歲、1-3歲、3-6歲的患兒采用噪聲指數(shù)分別為11、14、16時(shí)所掃描重建的圖像既滿足診斷需求,又顯著降低患兒?jiǎn)未屋椛鋭┝?為各年齡階段噪聲指數(shù)的最大臨界值。臨床試驗(yàn):影像噪聲隨著ASi R重建技術(shù)權(quán)重的增加而降低,影像SNR隨著ASi R重建技術(shù)權(quán)重的增加而增加,影像主觀質(zhì)量評(píng)價(jià)得分先隨著ASi R重建技術(shù)權(quán)重的增加而增加,當(dāng)達(dá)到最佳權(quán)重范圍后會(huì)隨著ASiR重建技術(shù)權(quán)重的增加而降低;0-1歲患兒影像ASiR最佳權(quán)重肺窗為50%、縱隔窗為40%;1-3歲患兒影像ASiR最佳權(quán)重肺窗為60%、縱隔窗為50%;3-6歲患兒影像ASiR最佳權(quán)重肺窗為70%、縱隔窗為60%。結(jié)論:在學(xué)齡前兒童胸部低劑量CT掃描中,應(yīng)用ASiR迭代重建技術(shù)能顯著提高影像圖像質(zhì)量,降低影像噪聲,0-1歲患兒影像ASiR最佳權(quán)重肺窗為50%、縱隔窗為40%;1-3歲患兒影像ASiR最佳權(quán)重肺窗為60%、縱隔窗為50%;3-6歲患兒影像ASiR最佳權(quán)重肺窗為70%、縱隔窗為60%。
[Abstract]:Objective: to evaluate the value of adaptive statistical iterative reconstruction technique (ASiR) in chest CT scanning of preschool children. Methods: clinical preclinical trial: 80 children aged 0-1 years old with CT were randomly divided into 4 groups, each group consisted of 20 children aged 1-3 years with chest CT, and were randomly divided into 7 groups, each group consisted of 20 children aged 3 to 6 years old, 180 children with chest CT were randomly divided into 9 groups. The preset range of noise index is 9-17. All of them adopt Z-axis automatic tube current regulation technique, the voltage of the tube is 100kV, the current of the tube is 20-150m Agna FBP reconstruction, the noise of image SNR, image is compared and analyzed under different noise index conditions, and the image quality is evaluated. To find the maximum critical value of noise-index to meet the diagnostic requirements of children with different age groups. Clinical trial: 30 cases of children aged 0-1 years old and 1-3 years old and 3-6 years old were examined by plain enhanced chest CT. The preset noise index of children aged 0-1 years was 12 ~ 1-3 years old. The preset noise index of children aged 153-6 years was 17. The Z-axis automatic tube current regulation technique was used. The voltage of the tube is 100kV, the current of the tube is 20-150mA, the default noise index of the children aged 0-6 years is 9, the other scanning parameters are the same as those of the plain scan sequence, the data of the enhanced scan sequence are reconstructed by FBP algorithm. Using adaptive statistical iterative reconstruction technique (ASiR) to reconstruct children's chest plain scan sequence data, 11 groups of images, such as 0% -100%, were reconstructed with 10% step value and 0% 0% respectively, which was the traditional FBP reconstruction algorithm. Comparing and analyzing the image SNR, image noise under the condition of different weight ASi R reconstruction technology, and analyzing and comparing the subjective quality of each group of images, To explore the relationship between ASiR reconstruction techniques with different weights and the quality of chest CT images in children aged 0-6 years, and to find out the best weight range of ASiR reconstruction techniques. Results: in clinical pre-trial, the noise index of children aged 1-3 years and 3-6 years were 1114, respectively. The reconstructed images scanned at 16:00 not only satisfied the diagnostic needs, but also significantly reduced the single dose of radiation, which was the maximum critical value of noise index in each age stage. Clinical trial: the image noise decreased with the increase of the weight of ASi R reconstruction technology, the image SNR increased with the increase of the weight of ASi R reconstruction technology, and the evaluation score of image subjective quality first increased with the increase of the weight of ASi R reconstruction technology. When the optimal weight range is reached, it will be reduced with the increase of the weight of ASiR reconstruction technique. The best weight lung window of ASiR for children aged 0-1 years is 50, the mediastinal window is 400-1-3 years old, the best weight lung window of ASiR is 60th and the mediastinal window is 500-6 years old. The best weight for ASiR is 70 for lung window and 60 for mediastinal window. Conclusion: in low dose CT scanning of preschool children, the application of ASiR iterative reconstruction technique can significantly improve the image quality. The best weight lung window of ASiR for children aged 0-1 years was 50g, the best weighted lung window of ASiR for children aged 1-3 years was 600.The best weighted lung window of ASiR for children aged 3-6 years was 700.The best weight lung window for mediastinal window was 600.The best weight lung window for mediastinal window was 60mm for children aged 3-6 years.
【學(xué)位授予單位】:西南醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類(lèi)號(hào)】:R816.92

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