【摘要】：目的探討宮頸癌放療中采用加速器機(jī)載千伏級(jí)錐形束CT(kV-CBCT)影像進(jìn)行劑量計(jì)算的準(zhǔn)確性和可行性。方法分別于CT模擬機(jī)和kV-CBCT上掃描CIRS-062電子密度模體,獲得電子密度模體影像及計(jì)劃CT(pCT)和kV-CBCT的CT值-相對(duì)電子密度曲線,采用治療計(jì)劃系統(tǒng)計(jì)算劑量。選取9例宮頸癌患者的調(diào)強(qiáng)治療計(jì)劃,并將計(jì)劃移植至模體和患者的pCT和kV-CBCT影像進(jìn)行劑量計(jì)算,比較劑量差異及劑量分布情況。結(jié)果 kV-CBCT的CT值經(jīng)多次重復(fù)測(cè)量最大變化≤3%;kV-CBCT的CT值-相對(duì)電子密度曲線與pCT相比,低密度組織的差異較小,高密度者差異相對(duì)較大。在對(duì)模體的劑量計(jì)算中,pCT和kV-CBCT的劑量差異為0.7%~2.5%,平均(1.23±0.55)%;而在對(duì)宮頸癌患者的劑量計(jì)算中,劑量差異為0.5%~1.8%,平均(0.84±0.44)%;劑量分布的一致性均較好。結(jié)論宮頸癌放療中采用kV-CBCT影像進(jìn)行劑量計(jì)算是可行的。
[Abstract]:Objective to investigate the accuracy and feasibility of dose calculation using accelerator airborne KV conical beam CT (kV-CBCT) in cervical cancer radiotherapy. Methods the electron density motifs of CIRS-062 were scanned on CT simulator and kV-CBCT, respectively. The CT values and relative electron density curves of CT (pCT) and kV-CBCT were obtained. The dose was calculated by the treatment plan system. Nine patients with cervical cancer were selected for intensity modulation treatment plan. The dose difference and dose distribution were compared by transplanting the plan to the motif and the pCT and kV-CBCT images of the patients. Results the CT value of kV-CBCT was measured repeatedly. The difference of CT value and relative electron density curve of kV-CBCT was smaller than that of pCT, and the difference of high-density tissue was larger than that of low-density tissue. The dose difference between PCT and kV-CBCT was 0.72.5, average (1.23 鹵0.55), but in the dose calculation of cervical cancer patients, the dose difference was 0.5 ~ 1.8 and (0.84 鹵0.44), and the consistency of dose distribution was good. Conclusion it is feasible to calculate the dose of cervical cancer by kV-CBCT imaging.
【作者單位】： 汕頭大學(xué)醫(yī)學(xué)院附屬腫瘤醫(yī)院放療科;
【分類號(hào)】：R737.33;R730.44

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相關(guān)期刊論文 前2條

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本文編號(hào)：2166746