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基于EPID的容積旋轉(zhuǎn)調(diào)強(qiáng)放療絕對(duì)劑量驗(yàn)證探討

發(fā)布時(shí)間:2018-06-23 14:04

  本文選題:電子射野影像裝置 + 容積調(diào)強(qiáng); 參考:《醫(yī)療衛(wèi)生裝備》2016年08期


【摘要】:目的:探討電子射野影像裝置(electronic portal imaging device,EPID)用于容積旋轉(zhuǎn)調(diào)強(qiáng)放療(volumetric modulated arc therapy,VMAT)絕對(duì)劑量驗(yàn)證的可行性與在臨床應(yīng)用中的意義。方法 :隨機(jī)選取100例患者的VMAT治療計(jì)劃,用Eclipse軟件導(dǎo)出EPID計(jì)劃和水模體驗(yàn)證計(jì)劃等中心平面的通量圖。在2幅通量圖中對(duì)應(yīng)位置處,各隨機(jī)選取30個(gè)待測(cè)量絕對(duì)劑量點(diǎn)(靶區(qū)內(nèi)6個(gè),靶區(qū)外擴(kuò)5、10、20、30、50 mm的區(qū)域內(nèi)和有效探測(cè)范圍內(nèi)各4個(gè)點(diǎn)),按照選取位置的不同將這些劑量點(diǎn)分成7組,每個(gè)點(diǎn)均測(cè)量EPID和指形電離室實(shí)測(cè)值,用單因素F檢驗(yàn)比較2種方法7組數(shù)據(jù)的計(jì)劃值與實(shí)測(cè)值準(zhǔn)確率的差異。結(jié)果 :7組劑量點(diǎn)的絕對(duì)劑量驗(yàn)證結(jié)果準(zhǔn)確率基本均在98%以上,2種方法測(cè)量的7組數(shù)據(jù)的準(zhǔn)確率均無(wú)統(tǒng)計(jì)學(xué)差異(F=0.032-3.189,P0.05)。結(jié)論:EPID具有在線實(shí)時(shí)劑量驗(yàn)證的潛力和明顯優(yōu)勢(shì),能夠大大提高多點(diǎn)絕對(duì)劑量驗(yàn)證的效率,可以用于VMAT治療絕對(duì)劑量的驗(yàn)證。
[Abstract]:Objective: to investigate the feasibility and clinical significance of (electronic portal imaging devicereal pid (EPID) in absolute dose verification of (volumetric modulated arc therapeutic VMAT. Methods: 100 patients with VMAT were randomly selected and the flux maps of EPID plan and water model experience plan were derived by Eclipse software. At the corresponding position in two flux maps, 30 absolute dose points to be measured were randomly selected (6 in target region, 6 in target region). These dose points were divided into 7 groups according to the selected position. EPID and finger ionization chamber were measured at each point. A single factor F test was used to compare the difference between the planned values and the actual values of 7 groups of data of the two methods. Results there was no significant difference in the accuracy of absolute dose verification between the 7 groups (F0. 032-3. 189). The accuracy rate of absolute dose verification was above 98% (F0. 032-3. 189) in the 7 groups (F0. 032-3. 189). Conclusion: EPID has the potential and obvious advantage of on-line real-time dose verification. It can greatly improve the efficiency of multi-point absolute dose verification and can be used to verify the absolute dose of VMAT.
【作者單位】: 武警后勤學(xué)院附屬醫(yī)院放療中心;天津大學(xué)精密儀器與光電子工程學(xué)院;武警后勤學(xué)院人體解剖與組織胚胎學(xué)教研室;
【基金】:武警后勤學(xué)院附屬醫(yī)院種子基金項(xiàng)目(FYM201620,FYQ201608)
【分類號(hào)】:R730.55
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本文編號(hào):2057364

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