本文選題：跟腱 + 腱病�。� 參考：《中國運(yùn)動(dòng)醫(yī)學(xué)雜志》2017年11期

【摘要】：跟腱腱病是跟腱的過度使用性損傷,其具體發(fā)病機(jī)制和病因尚不清楚。目前認(rèn)為是一個(gè)多因素導(dǎo)致的疾病,分為內(nèi)因和外因。其中,基因因素是重要的內(nèi)因之一,也是目前研究的熱點(diǎn)。已發(fā)現(xiàn)白細(xì)胞介素1(IL-1)、腫瘤壞死因子α(TNF-α)、細(xì)胞素-金屬基質(zhì)蛋白酶(MMPs)、膠原蛋白基因COL5A1等基因與跟腱腱病有關(guān)。明確跟腱腱病與易感基因的具體機(jī)制有利于該疾病的治療和預(yù)后。
[Abstract]:Achilles tendon disease is an overuse injury of Achilles tendon. The pathogenesis and etiology of Achilles tendon are unclear. The disease is now considered to be a multifactorial disease, divided into internal and external causes. Among them, gene factor is one of the important internal factors, and it is also the hot spot of current research. Interleukin-1 (IL-1), tumor necrosis factor- 偽 (TNF- 偽), cytokine metalloproteinases (MMPs) and collagen gene COL5A1 have been found to be associated with Achilles tendon disease. Understanding the specific mechanism of Achilles tendon disease and susceptibility gene is beneficial to the treatment and prognosis of the disease.
【作者單位】： 復(fù)旦大學(xué)附屬華山醫(yī)院運(yùn)動(dòng)醫(yī)學(xué)科;
【分類號(hào)】：R873
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本文編號(hào)：2053484