ROC曲線評(píng)價(jià)雙源CT小腸造影對(duì)克羅恩病活動(dòng)性評(píng)估的診斷價(jià)值
發(fā)布時(shí)間:2018-05-30 23:40
本文選題:CTE + 克羅恩病; 參考:《臨床放射學(xué)雜志》2015年11期
【摘要】:目的探討雙源CT口服法小腸CT造影(CTE)檢查對(duì)克羅恩病(CD)活動(dòng)性評(píng)估的應(yīng)用價(jià)值。方法回顧性分析116例確診為CD患者的CTE影像資料,評(píng)估患者腸壁異常增厚,腸黏膜異常強(qiáng)化,腸腔狹窄,木梳征,腸系膜增大的淋巴結(jié),動(dòng)脈期肝臟異常灌注,瘺道、潰瘍及膿腫等情況,并進(jìn)行CTE綜合評(píng)分。以臨床活動(dòng)性(基于CD活動(dòng)性指數(shù)、血清炎性指標(biāo)、內(nèi)鏡檢查)作為金標(biāo)準(zhǔn),應(yīng)用ROC曲線分析CTE綜合評(píng)分對(duì)CD活動(dòng)性判斷的診斷效能及最佳診斷分界值。結(jié)果 ROC曲線分析示曲線下面積(AUC)為0.881(P=0.000),最佳診斷分界值為6分,CTE綜合評(píng)分≥6分時(shí),CTE診斷CD處于活動(dòng)期,敏感度為80.8%,特異度為83.3%,誤診率為16.7%。結(jié)論CTE綜合評(píng)分方法對(duì)于CD的活動(dòng)性判斷有較高的診斷效能。
[Abstract]:Objective to evaluate the diagnostic value of dual source CT oral enterography (CTE) in evaluating the activity of Crohn's disease (Crohn's disease). Methods the CTE imaging data of 116 patients with CD were retrospectively analyzed. The abnormal thickening of intestinal wall, abnormal enhancement of intestinal mucosa, stenosis of intestinal cavity, wood comb sign, enlarged lymph nodes of mesentery, abnormal hepatic perfusion and fistula in arterial phase were evaluated. Ulcers and abscesses were evaluated by CTE. Clinical activity (based on CD activity index, serum inflammatory index, endoscopy) was used as gold standard. ROC curve was used to analyze the diagnostic efficacy and optimal diagnostic threshold of CTE comprehensive score for CD activity. Results the ROC curve analysis showed that the area under the curve was 0.881p 0.000, and the best diagnostic threshold was that the diagnostic CD was active, sensitivity was 80.8, specificity was 83.3 and the misdiagnosis rate was 16.7when the comprehensive score of CTE was 6 minutes or more. Conclusion the CTE comprehensive scoring method has high diagnostic efficacy in the diagnosis of CD activity.
【作者單位】: 南方醫(yī)科大學(xué)南方醫(yī)院影像中心;南方醫(yī)科大學(xué)南方醫(yī)院消化內(nèi)科;南方醫(yī)科大學(xué)生物統(tǒng)計(jì)學(xué)系;
【分類號(hào)】:R574.62;R816.5
【參考文獻(xiàn)】
相關(guān)期刊論文 前1條
1 朱炯;許建榮;朱震亞;龔紅霞;鐘U,
本文編號(hào):1957357
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