發(fā)布時間：2018-05-10 16:34

  本文選題：寶石能譜CT + 低劑量　； 參考：《吉林大學(xué)》2014年碩士論文

【摘要】：目的： 探討寶石能譜CT低照射劑量評價肺功能的可行性。 材料與方法： 隨機抽取2014年1月1日至2014年3月20于我院體檢人員60名，分為正常照射劑量組（NI=11）及低照射劑量組（NI=18）。正常照射劑量組受檢者30例，其中男20例，女10例，年齡范圍20~61歲，平均年齡40.8±10.8歲；低照射劑量組（NI=18）受檢者30例，其中男性16例，女性14例，年齡范圍24~62歲，平均年齡為44.8±11.1歲。所有受檢者行寶石能譜CT胸部吸氣末屏氣掃描，利用后處理軟件ThoracicVCAR分析圖像數(shù)據(jù)并測量右肺上葉尖段氣道壁平均厚度（AverageWall Thickness,WTAvg）、管徑厚度與外徑比值(Wall Thickness/AirwayDiameter,WT/D)、氣道壁面積與氣道總面積比值(Wall AreaRatio,WAR)、氣道壁面積（Wall area,WA）；測量出雙肺各CT值區(qū)域（分為-1024~-910Hu，-910~-800Hu，-800~-700Hu，-700Hu）肺像素指數(shù)（pixel index，，PI）,評估兩組各測量參數(shù)間有無統(tǒng)計學(xué)差異。記錄兩組受檢者CT容積劑量指數(shù)（CTDIvol）、劑量長度乘積（DLP）并計算有效劑量（ED）。 結(jié)果： 利用spss19.0軟件分析實驗數(shù)據(jù)，經(jīng)配對T檢驗后得出：兩組受檢者右肺上葉尖段氣道參數(shù)WTAvg、WT/D、WAR、WA間p值分別為0.065、0.559、0.585、0.131；兩組受檢者雙肺各區(qū)域像素指數(shù)PI-1024~-910Hu、PI-910~-800Hu、PI-800~-700Hu、PI-700Hu間P值分別為0.262、0.817、0.542、0.889。兩組各項數(shù)據(jù)間均無統(tǒng)計學(xué)差異（p0.05）。正常劑量組、低劑量組ED分別為4.99±1.37、1.92±0.68，低劑量組ED較正常劑量組降低61.52%。 結(jié)論： 寶石CT低照射劑量（NI=18）評價肺功能可行。
[Abstract]:Objective: Objective: to evaluate the feasibility of low dose gemstone CT in evaluating pulmonary function. Materials and methods: From January 1, 2014 to March 20, 2014, 60 medical examiners in our hospital were randomly divided into normal irradiation dose group and low dose group. 30 patients (male 20, female 10, mean age 40.8 鹵10.8) in the normal radiation dose group, and the low dose group (16 males and 14 females, with an average age of 44.8 鹵11.1 years). All subjects were scanned by gemstone energy dispersive computed tomography (EDS) at the end of inspiratory breath holding. Using post-processing software ThoracicVCAR to analyze the image data and to measure the mean thickness of the airway wall in the upper apical segment of the right lung (AverageWall Thicknessy WTAvgn), the ratio of diameter thickness to outer diameter, Wall thickness to outer diameter ratio, Wall area to total area of the airway, Wall area of the upper lobe of the right lung, and the area of the airway wall to measure the area of the two lungs, and to measure the ratio of the wall area to the total area of the airway. The pixel index of each CT value region (divided into -1024 ~ 910Hu-910Hu-800 Hu-800 Hu-800 Hu-700 Hu-700 Hu-700 Hu-7H) lung pixel index was used to evaluate the statistical difference between the two groups. The CT volumetric dose index (CTDIvoll), dose length product (DLPP) and effective dose (EDV) were recorded in the two groups. Results: Spss19.0 software was used to analyze the experimental data. After paired T test, the following results were obtained: the airway parameters of the right upper pulmonary apical segment in the two groups were as follows: the value of the WTAvgGV WTP / WARWA was 0.065 0. 559 0. 585% 0.131, and the pixel index of each region of the lung was PI-1024-910Hu-910Hu-800 Hu-PI-800 Hu-700 Hu value of 0.2620.817U 0.5420.80.88898.The two groups were divided into two groups, and the results showed that the mean values of the two groups were 0.2620.817 and 0.5420.8889, respectively, and the pixel index of the two groups was PI-1024-910Hu-910Hu-800 Hu-PI-800, PI-700Hu. There was no statistical difference between the two groups (p 0.05). Ed in normal dose group and low dose group were 4.99 鹵1.37 and 1.92 鹵0.68 respectively. Ed in low dose group was 61.5222lower than that in normal dose group. Conclusion: The evaluation of lung function by low dose sapphire CT was feasible.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R816.41

【參考文獻】

相關(guān)期刊論文 前10條

1 馬秀梅;;64層螺旋CT肺容積成像對慢性阻塞性肺疾病的臨床應(yīng)用價值[J];安徽醫(yī)學(xué);2013年01期

2 韓萍,許景紅,楊帆,馮敢生;螺旋CT結(jié)合呼吸門控對肺部形態(tài)及有關(guān)參數(shù)與功能關(guān)系的研究[J];臨床放射學(xué)雜志;1999年06期

3 沈泉,張志勇;肺功能的螺旋CT分析現(xiàn)狀與進展[J];中國臨床醫(yī)學(xué);2004年02期

4 伍建林,沈慧聰,宋清偉,張麗芝,李廣偉,于日新;健康成人肺臟在動態(tài)螺旋CT掃描中正常表現(xiàn)的定量研究[J];中國臨床醫(yī)學(xué)影像雜志;2001年04期

5 葉彩兒;葉民;吳碎英;吳恩福;陳偉建;;CT肺功能像素指數(shù)對COPD的肺功能評估及與肺功能的相關(guān)性分析[J];中國臨床醫(yī)學(xué)影像雜志;2008年11期

6 何一曼;王鎮(zhèn)山;;慢性阻塞性肺疾病患者氣道壁厚度與肺功能的關(guān)系[J];中外醫(yī)療;2012年31期

7 韓曉雨;葛瑩;李智勇;;CT肺功能成像與其臨床應(yīng)用[J];中國組織工程研究與臨床康復(fù);2011年04期

8 沈慧聰,伍建林,郎志謹,苗延巍,劉義軍,張曉文;動態(tài)CT掃描在慢性阻塞性肺病中的應(yīng)用研究[J];中國醫(yī)學(xué)計算機成像雜志;2003年04期

9 江小鵬;武志峰;鄂林寧;;COPD患者64排螺旋CT定量與肺功能相關(guān)性的研究[J];中國醫(yī)療前沿;2012年06期

10 李一鳴,祁吉,李云卿,姜濱,陳新娟;多層螺旋CT對早、中期慢性阻塞性肺疾病氣道改變的檢查及其病理基礎(chǔ)[J];診斷學(xué)理論與實踐;2005年04期

本文編號：1870051