本文選題：過敏反應(yīng) + 冠狀血管造影術(shù)　； 參考：《放射學(xué)實踐》2015年07期

【摘要】：目的:探討行冠狀動脈CT血管成像(CCTA)時使用碘對比劑的急性速發(fā)型過敏反應(yīng)發(fā)生率及其程度,并對過敏反應(yīng)在患者性別、年齡和危險因素分布的差異作出初步分析。方法:本組共入選接受CCTA檢查的連續(xù)患者37109例,男22636例(61%),女14473例(39%),年齡27~85歲(平均53.2±12.7歲)。根據(jù)Ring和Messmer提出的碘過敏反應(yīng)診斷標(biāo)準(zhǔn),將急性速發(fā)型(60min)過敏反應(yīng)由輕到重分為Ⅰ~Ⅳ級,登記患者的過敏反應(yīng)發(fā)病情況。獨立樣本采用t檢驗,分類變量比較采用卡方檢驗。結(jié)果:37109例患者中共發(fā)生急性速發(fā)型過敏反應(yīng)124例(0.334%),其中Ⅰ~Ⅳ級所占比率分別為96.774%(120/124),2.419%(3/124),0.806%(1/124)和0。Ⅰ~Ⅳ級過敏反應(yīng)在所有患者中的發(fā)生率分別為0.323%(120/37109)、0.008%(3/37109)、0.003%(1/37109)和0(χ2=214.345,P0.001)。進一步分層顯示男性過敏反應(yīng)發(fā)生率為0.314%(71/22636),與女性的發(fā)生率0.366%(53/14473)差異沒有統(tǒng)計學(xué)意義(χ2=0.732,P=0.392);以本組平均年齡為53歲分組,低年齡組(53歲)過敏反應(yīng)發(fā)生率為0.335%(51/15238),與高年齡組(≥53歲)的發(fā)生率0.334%(73/21871)差異沒有統(tǒng)計學(xué)意義(χ2=0.432,P=0.926)。過敏組患者在哮喘、食物過敏史、碘過敏史及腎功能不全的發(fā)病率均高于無過敏患者,兩組間差異具有統(tǒng)計學(xué)意義(P均0.05)。結(jié)論:行CCTA掃描時常規(guī)使用的碘對比劑有一定的急性速發(fā)型過敏反應(yīng)發(fā)生,但發(fā)生率低且多為輕度的I級;碘過敏發(fā)生率在不同性別和年齡組并非存在差異,但在有哮喘、食物過敏史、碘過敏史及腎功能不全的高危險因素患者中的發(fā)病率較高。
[Abstract]:Objective: to investigate the incidence and extent of acute rapid allergic reaction with iodine contrast agent during coronary artery CT angiography (CCTA), and to analyze the difference of sex, age and risk factors in patients with acute allergic reaction. Methods: a total of 37109 consecutive patients with CCTA were enrolled in this study, including 22636 males and 14473 females, aged 2785 years (mean 53.2 鹵12.7 years). According to the diagnostic criteria of iodine anaphylaxis put forward by Ring and Messmer, the acute quick-onset allergic reaction was divided from light to severe into grade 鈪，

本文編號：1804595