本文選題：睡眠呼吸暫停 + 阻塞性　； 參考：《中國(guó)全科醫(yī)學(xué)》2017年03期

【摘要】：目的探討阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)對(duì)患者上氣道咽側(cè)壁的厚度、腮腺密度和頜下脂肪的影響。方法收集南昌大學(xué)第一附屬醫(yī)院2013年10月—2014年10月經(jīng)多導(dǎo)睡眠圖(PSG)監(jiān)測(cè)確診為OSAHS的成年男性患者52例為OSAHS組,同期選取本院行頸部CT掃描的正常成年男性32例為對(duì)照組。采用128層螺旋CT進(jìn)行上氣道掃描,分別測(cè)量OSAHS組清醒狀態(tài)下和閉口堵鼻(Muller)試驗(yàn)下及對(duì)照組清醒狀態(tài)下軟腭區(qū)、舌后區(qū)、會(huì)厭后區(qū)的左右咽側(cè)壁厚度,同時(shí)測(cè)量?jī)山M清醒狀態(tài)下左右腮腺密度和頜下脂肪體積。結(jié)果清醒狀態(tài)下,OSAHS組軟腭區(qū)、舌后區(qū)、會(huì)厭后區(qū)左右咽側(cè)壁厚度均大于對(duì)照組(P0.05)。OSAHS組清醒狀態(tài)下軟腭區(qū)、舌后區(qū)左右咽側(cè)壁厚度均小于Muller試驗(yàn)下(P0.05);OSAHS組清醒狀態(tài)下與Muller試驗(yàn)下會(huì)厭后區(qū)左右咽側(cè)壁厚度比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)。清醒狀態(tài)下,OSAHS組左右腮腺密度低于對(duì)照組,頜下脂肪體積大于對(duì)照組(P0.05)。結(jié)論上氣道咽側(cè)壁厚度、頜下脂肪體積、腮腺脂肪浸潤(rùn)在OSAHS的發(fā)生發(fā)展中均有顯著變化,對(duì)其發(fā)病機(jī)制的進(jìn)一步研究有重要意義。
[Abstract]:Objective to investigate the effects of obstructive sleep apnea hypopnea syndrome (OSAHS) on the thickness of lateral wall of upper airway parotid gland density and submaxillary fat in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods 52 adult male patients diagnosed as OSAHS by polysomnography from October 2013 to October 2014 in the first affiliated Hospital of Nanchang University were selected as OSAHS group. 32 normal adult males who underwent cervical CT scanning were selected as control group.The upper airway was scanned by 128-slice spiral CT. The thickness of left and right pharyngeal lateral wall was measured in OSAHS group under awake condition and closed nasal occlusion test and in control group under awake state, posterior lingual area and posterior epiglottic area.The density of left and right parotid gland and submandibular fat volume were measured in both groups.Results the thickness of left and right pharyngeal lateral wall in OSAHS group was higher than that in control group (P 0.05).The thickness of left and right pharynx lateral wall in the posterior part of tongue was less than that in the Muller test. There was no significant difference in the thickness of left and right pharynx lateral wall between the right and left pharyngeal lateral wall of the posterior epiglottic area under the Muller test.The density of parotid gland in OSAHS group was lower than that in control group, and the submaxillary fat volume was larger than that in control group (P 0.05).Conclusion the thickness of pharynx lateral wall of upper airway submaxillary fat volume and fat infiltration of parotid gland have significant changes in the occurrence and development of OSAHS. It is of great significance to further study the pathogenesis of OSAHS.
【作者單位】： 南昌大學(xué)第一附屬醫(yī)院影像科;
【基金】：江西省自然科學(xué)基金資助項(xiàng)目(20132BAB205100)
【分類號(hào)】：R766;R816.96

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