本文選題：CT灌注掃描　切入點(diǎn)：尤瑞克林　出處：《中國老年學(xué)雜志》2015年01期 　論文類型：期刊論文

【摘要】：目的探討CT灌注掃描技術(shù)(CTPI)對尤瑞克林治療老年急性期腦梗死的臨床效果。方法 2012年1月至2014年1月選取168例經(jīng)頭部CT或磁共振成像(MRI)確診為急性期腦梗死的老年患者,隨機(jī)分為常規(guī)治療組及尤瑞克林組各84例,常規(guī)治療組口服阿司匹林,同時(shí)給予奧扎格雷鈉靜脈滴注治療,尤瑞克林組在常規(guī)治療基礎(chǔ)上靜脈滴注尤瑞克林,分別于治療前后對兩組患者行CTPI,觀察兩組患者治療前后中心區(qū)及半暗帶區(qū)腦灌注成像相對比值。對比兩組患者治療效果及治療前后腦梗死面積及神經(jīng)功能缺損評分(NIHSS)改善情況。結(jié)果尤瑞克林組總有效率(92.86%)高于常規(guī)治療組(76.19%)(P0.05)。兩組患者治療后中心區(qū)及半暗帶區(qū)中腦血容量(CBV)、腦血流量(CBF)、達(dá)峰時(shí)間(TTP)均高于治療前(P0.05),且尤瑞克林組治療后中心區(qū)及半暗帶區(qū)中CBV、CBF、TTP均高于常規(guī)治療組(P0.05)。尤瑞克林組治療后梗死面積及NIHSS評分顯著少于常規(guī)治療組。結(jié)論通過CT灌注掃描可觀察尤瑞克林對老年急性期腦梗死患者病灶中心區(qū)及半暗帶區(qū)血流灌注的改善情況,對評價(jià)腦梗死患者預(yù)后具有重要的意義。
[Abstract]:Objective to investigate the clinical effect of CT perfusion scanning technique (CTPI) in the treatment of acute cerebral infarction in elderly patients. Methods from January 2012 to January 2014, 168 elderly patients diagnosed as acute cerebral infarction by CT or Mr imaging were selected. They were randomly divided into routine treatment group (n = 84) and eurekline group (n = 84). Aspirin was given orally in routine treatment group and sodium ozagrel was given intravenously. CTPI was performed before and after treatment to observe the relative ratio of cerebral perfusion imaging in the central and penumbra regions before and after treatment in the two groups. The effect of treatment and the assessment of cerebral infarct size and neurological deficit before and after treatment were compared between the two groups. Results the total effective rate of Eurekline group (92.86) was higher than that of routine treatment group (76.19%) (P 0.05). After treatment, CBVV, CBFV, CBFV, TTPwere higher in the central and penumbra regions of the two groups than in the pre-treatment (P 0.05). After treatment, the TTP of CBV and CBF in the central and penumbra regions of the group was higher than that in the routine treatment group (P 0.05). The infarct size and NIHSS score in the eucrine group after treatment were significantly lower than those in the routine treatment group. Conclusion the CT perfusion scan can be used to observe the effect of eurethrin on the elderly acute. The improvement of blood perfusion in the central and penumbra regions of patients with cerebral infarction, It is of great significance to evaluate the prognosis of patients with cerebral infarction.
【作者單位】： 滄州市中心醫(yī)院神經(jīng)內(nèi)五科;
【分類號】：R743.3;R816.2

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