256層螺旋CT冠狀動脈造影對高心率患者的成像質(zhì)量及診斷效率評價
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本文選題:256排多層螺旋CT 切入點:圖像質(zhì)量 出處:《吉林大學(xué)》2012年碩士論文 論文類型:學(xué)位論文
【摘要】:目的: 評估256層螺旋CT冠狀動脈造影中高心率患者的圖像質(zhì)量以及50%以上狹窄檢出率的準(zhǔn)確性。 材料與方法: 對31例于30天內(nèi)行冠狀動脈CT造影及傳統(tǒng)血管造影的患者進行回顧性分析,其中男17例,女14例。入組患者根據(jù)心率分為兩組,A組患者平均心率<75次/分,其中男性5例,女性8例,平均年齡(56.6±10.3)歲,B組患者平均心率≥75次/分,其中男性12例,女性6例,平均年齡(57.6±9.8)歲。所有患者均行256層螺旋CT回顧性心電門控成像。由兩名放射線科醫(yī)生進行圖像重建,并選擇最佳期相進行分析,對直徑大于1mm的冠狀動脈節(jié)段進行評估(1分為無運動偽影,5分為無法診斷)。圖像質(zhì)量的客觀評價包括軸位測量升主動脈水平冠狀動脈左主干的CT值及噪聲,對于管腔直徑狹窄大于50%的患者,進行血管造影檢查。對于冠狀動脈的前降支、回旋支、右冠狀動脈的圖像質(zhì)量及平均心率、心率波動進行線性相關(guān)分析。以血管造影為標(biāo)準(zhǔn),按節(jié)段及血管為基礎(chǔ)對CT冠狀動脈造影診斷的準(zhǔn)確性進行評估。 結(jié)果: A組的平均心率為(63.7±9.0)次/分, B組的平均心率為(82.9±5.8)次/分。因冠狀動脈解剖變異(32)及血管直徑過。7例),共有39個節(jié)段(7.4%)無法評估,其中A組有19個節(jié)段(6.2%),B組有20個節(jié)段(9%)。A組圖像質(zhì)量的主觀評分為(1.38±0.26),B組圖像質(zhì)量的主觀評分為(1.35±0.29),兩組無統(tǒng)計學(xué)差異(P=0.761)。A組圖像質(zhì)量的主觀評分為1的有259例(90.2%),B組圖像質(zhì)量的主觀評分為1的有158個節(jié)段(78.6%)。A組圖像質(zhì)量中有17個節(jié)段(6.0%)評分為2,而B組圖像質(zhì)量中有18個節(jié)段(9.0%)。圖像質(zhì)量評分為3的A組有4個節(jié)段(1.4%),B組有13個節(jié)段(6.5%)。所有圖像質(zhì)量評分均低于3分。兩名醫(yī)生對圖像的主觀評價有較強的一致性(κ=0.84,p 0.001)。所有冠狀動脈節(jié)段的圖像質(zhì)量評分與平均心率沒有相關(guān)性(r=0.176; P=0.344)。右冠狀動脈節(jié)段的圖像質(zhì)量評分與平均心率沒有相關(guān)性(r=0.122; P=0.513)。左冠狀動脈節(jié)段的圖像質(zhì)量評分與平均心率沒有相關(guān)性(r=0.123; P=0.510)。左回旋支各節(jié)段的圖像質(zhì)量評分與平均心率沒有相關(guān)性(r=0.157; P=0.398)。A組的平均心率波動為(4.9±2.2)次/分,B組的平均心率波動為(5.1±2.4)次/分,兩組心率波動統(tǒng)計學(xué)無差異(P=0.729)。冠狀動脈節(jié)圖像質(zhì)量與心率波動無相關(guān)性(r=-0.74; P=0.691)。對主觀評價而言,A組升主動脈的強化值為(362.2±72.8)HU,B組升主動脈的強化值為(354.1±68.6)HU,無統(tǒng)計學(xué)差異(P=0.755)。A、B兩組的圖像噪聲分別為22.2±4.9及21.3±4.6,無統(tǒng)計學(xué)差異(P=0.620)。大于50%狹窄的檢出中,以節(jié)段為基礎(chǔ)的A、B兩組的準(zhǔn)確率分別為97.1%(297/306)和95.0%(210/221),,敏感性分別為94.0%(47/50)和89.7%(26/29),特異性分別為97.7%(250/256)和96.8%(184/190)。以血管為基礎(chǔ)的A、B兩組的準(zhǔn)確率分別為92.6%(50/54)和94.9%(37/39),敏感性分別為96.4%(27/28)和95.2%(20/21),特異性分別為88.5%(23/26)和83.5%(15/18)。 結(jié)論: 心率快慢對256層螺旋CT冠狀動脈造影回顧性心電門控成像的影響較小,高心率患者CT造影的圖像質(zhì)量可以滿足診斷要求。256層螺旋CT冠狀動脈造影回顧性心電門控成像可以應(yīng)用于高心率患者,尤其是對β受體阻滯劑有禁忌癥的高心率患者。
[Abstract]:Objective:
To evaluate the image quality of patients with high cardiac rate in 256 slice spiral CT coronary angiography and the accuracy of more than 50% stenosis detection rates.
Materials and methods:
Of 31 patients in 30 days after coronary CT angiography and conventional angiography were retrospectively analyzed, including 17 cases of male, female 14 cases. Patients were divided into two groups according to heart rate, average heart rate of patients in group A < 75 / min, there were 5 males and 8 females, the average age (56.6 + 10.3), patients in the B group than the average heart rate of 75 beats per minute, there were 12 males and 6 females, the average age (57.6 + 9.8) years old. All patients underwent 256 slice spiral CT imaging. Retrospective ECG gated images were reconstructed by two radiologists, and select the best phase analysis of assessment of coronary artery segment diameter greater than 1mm (1 = no motion artifacts, 5 points can not be diagnosed). Image quality assessment including axial measurement of left main coronary artery ascending aortic CT value and the level of noise, the luminal diameter stenosis more than 50% patients, performed angiography for. The image quality and mean heart rate and the heart rate fluctuation of the anterior descending branch of the coronary artery, the circumflex artery and the right coronary artery were analyzed by linear correlation analysis. Based on angiography, the accuracy of CT coronary angiography was evaluated based on segments and vessels.
Result錛
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