256層螺旋CT冠狀動(dòng)脈造影對(duì)高心率患者的成像質(zhì)量及診斷效率評(píng)價(jià)
發(fā)布時(shí)間:2018-03-10 14:31
本文選題:256排多層螺旋CT 切入點(diǎn):圖像質(zhì)量 出處:《吉林大學(xué)》2012年碩士論文 論文類(lèi)型:學(xué)位論文
【摘要】:目的: 評(píng)估256層螺旋CT冠狀動(dòng)脈造影中高心率患者的圖像質(zhì)量以及50%以上狹窄檢出率的準(zhǔn)確性。 材料與方法: 對(duì)31例于30天內(nèi)行冠狀動(dòng)脈CT造影及傳統(tǒng)血管造影的患者進(jìn)行回顧性分析,其中男17例,女14例。入組患者根據(jù)心率分為兩組,A組患者平均心率<75次/分,其中男性5例,女性8例,平均年齡(56.6±10.3)歲,B組患者平均心率≥75次/分,其中男性12例,女性6例,平均年齡(57.6±9.8)歲。所有患者均行256層螺旋CT回顧性心電門(mén)控成像。由兩名放射線(xiàn)科醫(yī)生進(jìn)行圖像重建,并選擇最佳期相進(jìn)行分析,對(duì)直徑大于1mm的冠狀動(dòng)脈節(jié)段進(jìn)行評(píng)估(1分為無(wú)運(yùn)動(dòng)偽影,5分為無(wú)法診斷)。圖像質(zhì)量的客觀評(píng)價(jià)包括軸位測(cè)量升主動(dòng)脈水平冠狀動(dòng)脈左主干的CT值及噪聲,對(duì)于管腔直徑狹窄大于50%的患者,進(jìn)行血管造影檢查。對(duì)于冠狀動(dòng)脈的前降支、回旋支、右冠狀動(dòng)脈的圖像質(zhì)量及平均心率、心率波動(dòng)進(jìn)行線(xiàn)性相關(guān)分析。以血管造影為標(biāo)準(zhǔn),按節(jié)段及血管為基礎(chǔ)對(duì)CT冠狀動(dòng)脈造影診斷的準(zhǔn)確性進(jìn)行評(píng)估。 結(jié)果: A組的平均心率為(63.7±9.0)次/分, B組的平均心率為(82.9±5.8)次/分。因冠狀動(dòng)脈解剖變異(32)及血管直徑過(guò)。7例),共有39個(gè)節(jié)段(7.4%)無(wú)法評(píng)估,其中A組有19個(gè)節(jié)段(6.2%),B組有20個(gè)節(jié)段(9%)。A組圖像質(zhì)量的主觀評(píng)分為(1.38±0.26),B組圖像質(zhì)量的主觀評(píng)分為(1.35±0.29),兩組無(wú)統(tǒng)計(jì)學(xué)差異(P=0.761)。A組圖像質(zhì)量的主觀評(píng)分為1的有259例(90.2%),B組圖像質(zhì)量的主觀評(píng)分為1的有158個(gè)節(jié)段(78.6%)。A組圖像質(zhì)量中有17個(gè)節(jié)段(6.0%)評(píng)分為2,而B(niǎo)組圖像質(zhì)量中有18個(gè)節(jié)段(9.0%)。圖像質(zhì)量評(píng)分為3的A組有4個(gè)節(jié)段(1.4%),B組有13個(gè)節(jié)段(6.5%)。所有圖像質(zhì)量評(píng)分均低于3分。兩名醫(yī)生對(duì)圖像的主觀評(píng)價(jià)有較強(qiáng)的一致性(κ=0.84,p 0.001)。所有冠狀動(dòng)脈節(jié)段的圖像質(zhì)量評(píng)分與平均心率沒(méi)有相關(guān)性(r=0.176; P=0.344)。右冠狀動(dòng)脈節(jié)段的圖像質(zhì)量評(píng)分與平均心率沒(méi)有相關(guān)性(r=0.122; P=0.513)。左冠狀動(dòng)脈節(jié)段的圖像質(zhì)量評(píng)分與平均心率沒(méi)有相關(guān)性(r=0.123; P=0.510)。左回旋支各節(jié)段的圖像質(zhì)量評(píng)分與平均心率沒(méi)有相關(guān)性(r=0.157; P=0.398)。A組的平均心率波動(dòng)為(4.9±2.2)次/分,B組的平均心率波動(dòng)為(5.1±2.4)次/分,兩組心率波動(dòng)統(tǒng)計(jì)學(xué)無(wú)差異(P=0.729)。冠狀動(dòng)脈節(jié)圖像質(zhì)量與心率波動(dòng)無(wú)相關(guān)性(r=-0.74; P=0.691)。對(duì)主觀評(píng)價(jià)而言,A組升主動(dòng)脈的強(qiáng)化值為(362.2±72.8)HU,B組升主動(dòng)脈的強(qiáng)化值為(354.1±68.6)HU,無(wú)統(tǒng)計(jì)學(xué)差異(P=0.755)。A、B兩組的圖像噪聲分別為22.2±4.9及21.3±4.6,無(wú)統(tǒng)計(jì)學(xué)差異(P=0.620)。大于50%狹窄的檢出中,以節(jié)段為基礎(chǔ)的A、B兩組的準(zhǔn)確率分別為97.1%(297/306)和95.0%(210/221),,敏感性分別為94.0%(47/50)和89.7%(26/29),特異性分別為97.7%(250/256)和96.8%(184/190)。以血管為基礎(chǔ)的A、B兩組的準(zhǔn)確率分別為92.6%(50/54)和94.9%(37/39),敏感性分別為96.4%(27/28)和95.2%(20/21),特異性分別為88.5%(23/26)和83.5%(15/18)。 結(jié)論: 心率快慢對(duì)256層螺旋CT冠狀動(dòng)脈造影回顧性心電門(mén)控成像的影響較小,高心率患者CT造影的圖像質(zhì)量可以滿(mǎn)足診斷要求。256層螺旋CT冠狀動(dòng)脈造影回顧性心電門(mén)控成像可以應(yīng)用于高心率患者,尤其是對(duì)β受體阻滯劑有禁忌癥的高心率患者。
[Abstract]:Objective:
To evaluate the image quality of patients with high cardiac rate in 256 slice spiral CT coronary angiography and the accuracy of more than 50% stenosis detection rates.
Materials and methods:
Of 31 patients in 30 days after coronary CT angiography and conventional angiography were retrospectively analyzed, including 17 cases of male, female 14 cases. Patients were divided into two groups according to heart rate, average heart rate of patients in group A < 75 / min, there were 5 males and 8 females, the average age (56.6 + 10.3), patients in the B group than the average heart rate of 75 beats per minute, there were 12 males and 6 females, the average age (57.6 + 9.8) years old. All patients underwent 256 slice spiral CT imaging. Retrospective ECG gated images were reconstructed by two radiologists, and select the best phase analysis of assessment of coronary artery segment diameter greater than 1mm (1 = no motion artifacts, 5 points can not be diagnosed). Image quality assessment including axial measurement of left main coronary artery ascending aortic CT value and the level of noise, the luminal diameter stenosis more than 50% patients, performed angiography for. The image quality and mean heart rate and the heart rate fluctuation of the anterior descending branch of the coronary artery, the circumflex artery and the right coronary artery were analyzed by linear correlation analysis. Based on angiography, the accuracy of CT coronary angiography was evaluated based on segments and vessels.
Result錛
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