【摘要】：目的了解甘肅省10個(gè)藏區(qū)縣人群棘球蚴病流行情況。方法 2011年9月-2012年6月在甘肅省10個(gè)藏族自治州(縣)進(jìn)行分層隨機(jī)抽樣,每縣共抽取16個(gè)行政村。采用B超掃描的方法,開(kāi)展人群棘球蚴病流行情況調(diào)查。應(yīng)用SPSS 20.0軟件對(duì)調(diào)查結(jié)果進(jìn)行描述和統(tǒng)計(jì)學(xué)分析,患病檢出率比較采用χ~2檢驗(yàn)。結(jié)果共抽樣檢查37 815人,所有調(diào)查點(diǎn)均發(fā)現(xiàn)棘球蚴病例;以縣為單位的人群患病檢出率為0.05%~1.59%,平均0.59%(224/37 815);患病檢出率大于1%的縣分別為夏河縣1.59%(64/4 019)、瑪曲縣1.37%(44/3 206)、肅南縣1.20%(60/5 000)�？�?cè)巳耗行曰疾z出率為0.53%(108/20 276)、女性患病檢出率為0.66%(116/17 539),兩者間差異無(wú)統(tǒng)計(jì)學(xué)意義(χ~2=2.647,P0.05),但藏族女性(0.71%,93/13 146)和男性(0.46%,73/15 709)患病檢出率間差異有統(tǒng)計(jì)學(xué)意義(χ~2=7.372,P0.05)。不同年齡組間患病檢出率差異有統(tǒng)計(jì)學(xué)意義(χ~2=109.346,P0.05),其中20~歲組最低,為0.28%(19/6 687),80~歲組最高,為2.41%(4/166),患病檢出率曲線隨年齡增長(zhǎng)呈現(xiàn)增高趨勢(shì)。不同民族間患病檢出率差異無(wú)統(tǒng)計(jì)學(xué)意義(χ~2=1.710,P0.05),回族患病檢出率最高,為0.92%(5/546)。不同職業(yè)人群間患病檢出率差異有統(tǒng)計(jì)學(xué)意義(χ~2=33.345,P0.05),其中商人患病檢出率最高,為3.32%(2/62)。共發(fā)現(xiàn)細(xì)粒棘球蚴病223例,多房棘球蚴病1例,無(wú)混合感染病例。其中單臟器寄生占98.21%(220/224);累及肝臟占94.76%(217/229);單包囊占81.70%(183/224);60歲及以上年齡組中多包囊比例(28.57%,22/77)高于60歲以下組(12.93%,19/147),兩者間差異有統(tǒng)計(jì)學(xué)意義(χ~2=8.273,P0.05)。結(jié)論甘肅省10個(gè)藏區(qū)縣存在不同程度的細(xì)粒棘球蚴病流行,其中夏河縣、瑪曲縣、肅南縣流行嚴(yán)重。藏族女性、60歲以上者、商人是該病的重點(diǎn)干預(yù)人群。
[Abstract]:Objective to investigate the prevalence of echinococcosis in 10 Tibetan counties in Gansu province. Methods from September 2011 to June 2012, 10 Tibetan autonomous prefectures (counties) in Gansu Province were sampled by stratified random sampling. 16 administrative villages were sampled from each county. An investigation of the prevalence of echinococcosis was carried out by B-scan. The survey results were described and statistically analyzed by SPSS 20.0 software. 蠂 2 test was used to compare the prevalence of the disease. Results A total of 37,815 people were sampled, and the incidence of echinococcosis was found in all the investigation points. The detection rate of echinococcosis was 0.05% (0.59%) in the population in county, and 1.59% (64 / 4,019) in Xiahe county (64 / 4,019), 1.37% (44 / 3 206) in Sunan county, and 1.20% (605,000%) in Sunan county, respectively, in the county of Xiahe county (64 / 4,019), Maqu county (1.37%) and Sunan county (605,000%). The prevalence rate of male was 0.53% (108 / 20 276) and that of female was 0.66% (116 / 17 539). There was no significant difference between the two groups (蠂 ~ (2) 2.647), but there was significant difference between Tibetan women (0.71% / 13 146) and male (0.46% / 15 709). There was significant difference in the prevalence rate among different age groups (蠂 2 / 109.346P 0.05), among which the 20 ~ year old group was the lowest, 0.28% (19 / 6 687) was the highest (2.41%) (4 / 166). The prevalence rate curve showed an increasing trend with the increase of age. There was no significant difference in the prevalence rate among different nationalities (蠂 2 + 1.710%, P0.05), and the highest prevalence rate was 0.92% (5 / 546) in Hui nationality. There were significant differences in the prevalence rate among different occupational groups (蠂 ~ 2 ~ (2) ~ (33) 345), in which the prevalence rate of merchants was the highest (3.32%) (2 / 62). 223 cases of echinococcosis and 1 case of multilocularis echinococcosis were found. There were 98.21% (220 / 224) of single organ parasitism, 94.76% (21.7 / 229) of liver involvement and 81.70% (183 / 224) of single cyst in the age group of 60 years or older (28.57% 22 / 77) higher than those under 60 (12.933 / 19147). The difference between the two groups was statistically significant (蠂 ~ (2 / 28) 8.273). Conclusion Echinococcus granulosus is prevalent in 10 Tibetan counties in Gansu Province, including Xiahe County, Maqu County and Sunan County. Tibetan women over 60 years old, businessmen are the focus of intervention population.
【作者單位】： 甘肅省疾病預(yù)防控制中心;中國(guó)疾病預(yù)防控制中心寄生蟲(chóng)病預(yù)防控制所 世界衛(wèi)生組織熱帶病合作中心 科技部國(guó)家級(jí)熱帶病國(guó)際聯(lián)合研究中心 衛(wèi)生部寄生蟲(chóng)病原與媒介生物學(xué)重點(diǎn)實(shí)驗(yàn)室;
【基金】：甘肅省科技支撐計(jì)劃(No.1304FKCA120) 衛(wèi)生部寄生蟲(chóng)病原與媒介生物學(xué)重點(diǎn)實(shí)驗(yàn)室開(kāi)放課題(No.WSBKTKT201305) 國(guó)家自然科學(xué)基金(No.81201315) 國(guó)家傳染病重大專(zhuān)項(xiàng)(No.2009ZX10004-302)~~
【分類(lèi)號(hào)】：R181.3;R532.32

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