本文選題：乙型肝炎病毒 + 垂直傳播　； 參考：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年02期

【摘要】：目的評價(jià)乙肝疫苗和乙肝免疫球蛋白聯(lián)合免疫對乙肝病毒母嬰傳播的阻斷效果。方法從張家港市設(shè)有產(chǎn)科的所有醫(yī)院選取母親為乙肝病毒表面抗原(HBs Ag)陽性且已接種乙肝疫苗和乙肝免疫球蛋白的嬰幼兒512人,隨訪調(diào)查母親乙肝病毒感染情況,分娩方式等,并檢測嬰幼兒血清中HBs Ag和乙肝病毒表面抗體(HBs Ab)水平。結(jié)果調(diào)查嬰幼兒中,HBs Ag陽性率為1.76%,HBs Ab陽性率為87.11%。不同性別、不同分娩方式對嬰幼兒乙肝感染率的影響差異無統(tǒng)計(jì)學(xué)意義�！�12月齡、12月齡~和≥24月齡的嬰幼兒HBs Ab陽性率分別為100.00%、90.91%和84.62%。結(jié)論乙肝疫苗和乙肝免疫球蛋白阻斷HBs Ag陽性母親垂直傳播乙肝病毒效果顯著,嬰幼兒體液免疫水平隨月齡增加而逐步降低。
[Abstract]:Objective to evaluate the blocking effect of hepatitis B vaccine and hepatitis B immunoglobulin on mother-to-child transmission of hepatitis B virus. Methods A total of 512 infants were selected from all hospitals with obstetrics in Zhangjiagang city who were HBV surface antigen positive and vaccinated with hepatitis B vaccine and hepatitis B immunoglobulin, and their mothers were followed up to investigate the situation of hepatitis B virus infection and the way of delivery, etc. Serum HBs Ag and HBV surface antibody (HBs Abb) were detected. Results the positive rate of HBs Ag in infants was 1.76 and the positive rate of HBs Ab was 87.11. The positive rates of HBs Ab in infants 鈮，

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